Left-to-Right Pancreatoduodenectomy at Splenic Vessels for Locally Advanced Pancreatic Tumors with Portal Vein and Common Hepatic Artery Encasement.

Fiche publication

Date publication

janvier 2026

Journal

Annals of surgical oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BACHELLIER Philippe

Tous les auteurs :
Addeo P, Paul C, Marchitelli I, De Mathelin P, Bachellier P

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/41559467

Résumé

In locally advanced pancreatic adenocarcinomas (LA-PDAC) when both common hepatic artery and portal vein encasement coexist, classical right-to-left dissection with vascular resection is difficult to achieve. We describe an alternative approach named left-to-right pancreatoduodenectomy at splenic vessels in which the central part of the dissection is carried out last and the reversed splenic artery is used to reconstruct the hepatic artery. PATIENT AND METHODS: The patient was a 76-year-old woman with both transverse colonic cancer and LA-PDAC (common hepatic artery and portal vein encasement with venous cavernoma) who underwent 6 months of GEMOX induction treatment with carbohydrate antigen 19.9 (CA 19-9) normalization. Dissection steps included: (1) early mesenteric-portal shunting to bypass portal cavernoma; (2) mesenteric approach to the superior mesenteric antigen (SMA) with jejunal section and SMA isolation; (3) retropancreatic tunnel on the left of the SMA with pancreatic body section; (4) splenic vessel dissection with distal splenic artery section and a distal venous-spleno renal shunt fashioning; (5) proper and common hepatic artery section and reconstruction by splenic artery reversal; and (6) digestive reconstruction with pancreatogastrostomy. Right colectomy was performed en bloc because of synchronous colonic cancer.