Fiche publication
Date publication
novembre 2025
Journal
Journal of Crohn's & colitis
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
,
Pr GERMAIN Adeline
Tous les auteurs :
Migliorisi G, Delaplace R, Honap S, Germain A, Mouillot T, Peyrin-Biroulet L, Kotze PG
Lien Pubmed
Résumé
Surgery is a pivotal component of the management of Crohn's disease (CD), particularly in cases of disease-related complications or failure of medical therapy. However, the risk of short bowel syndrome following multiple large resections makes bowel preservation strategies a major therapeutic priority. This review gathers insights from a diverse group of IBD specialists, exploring the full spectrum of bowel-preserving strategies, from conservative surgical techniques and peri-operative optimization, to emerging innovations in robotic surgery. The therapeutic paradigm of treat-to-target and tight disease monitoring is shifting the focus from reactive interventions to proactive and personalised care. Looking ahead, the evolving implementation of multi-omics profiling and artificial intelligence holds promise to reshape the role of surgery in CD. Surgery should no longer be viewed solely as a response to complications, but rather as an individualized, biology-driven strategy that prioritizes bowel preservation. In this rapidly advancing field, innovation is measured not only by clinical outcomes but also by every centimetre of bowel preserved.
Mots clés
Crohn’s disease, bowel preservation, inflammatory bowel disease, short bowel syndrome, surgery
Référence
J Crohns Colitis. 2025 11 24;:
