Fiche publication
Date publication
octobre 2025
Journal
Annals of the rheumatic diseases
Auteurs
Membres identifiés du Cancéropôle Est :
Dr METZGER Daniel
,
Dr LAVERNY Gilles
,
Pr GENY Bernard
Tous les auteurs :
Debrut L, Giannini M, Quiring G, Perniola S, Rovito D, Keime C, Lannes B, Nadaj-Pakleza A, Chanson JB, Charles AL, Geny B, Metzger D, Laverny G, Meyer A
Lien Pubmed
Résumé
This study aims to characterise the molecular pathways underpinning perifascicular muscle fibre alterations to identify repositionable molecules for dermatomyositis (DM) treatment, and validate potential candidates in preclinical models.
Mots clés
Dermatomyositis, DM, IFN, Inclusion body myositis, IBM, KZR, PSMB8, Polymyositis, PM, antisynthetase syndrome, ASyS, experimental myositis, immune-mediated necrotising myopathy, IMNM, immunoproteasome, inflammatory myopathies, IIM, interferon, ixazomib, necrotising autoimmune myopathy, overlap myositis, proteasome, scleromyositis
Référence
Ann Rheum Dis. 2025 10 6;:
