Fiche publication


Date publication

novembre 2025

Journal

Neurology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BINQUET Christine


Tous les auteurs :
Arnould L, Soumaré A, D'Aoust T, Lima Rebouças SC, Bordes C, Crivello F, Korobelnik JF, Paques M, Sargurupremraj M, Mishra A, Zhu YC, Delcourt C, Helmer C, Khawaja A, Hysi P, Binquet C, Creuzot-Garcher C, Debette S

Résumé

Cerebral small vessel disease (cSVD), characterized by pathologic changes in the structure and function of small brain vessels, is detectable on brain MRI in the absence of clinical symptoms. However, imaging cerebral small vessels themselves in vivo remains costly and challenging. There is growing interest in investigating whether retinal microvascular imaging features could be proxies for changes in the brain microvasculature. Using a multipronged approach, we explored the relation of retinal microvascular characteristics with MRI markers of cSVD (MRI-cSVD).

Mots clés

Humans, Cerebral Small Vessel Diseases, diagnostic imaging, Aged, Male, Female, Retinal Vessels, diagnostic imaging, Microvessels, diagnostic imaging, Magnetic Resonance Imaging, White Matter, diagnostic imaging, Aged, 80 and over, Cohort Studies

Référence

Neurology. 2025 11 11;105(9):e214251