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Date publication
juillet 2025
Journal
European journal of clinical investigation
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ORTEGA DEBALLON Pablo
,
Dr PAIS DE BARROS Jean-Paul
,
Pr MASSON David
Tous les auteurs :
Nguyen M, Alvarez M, Berthoud V, Pallot G, Abagri S, Leleu D, Pais-De-Barros JP, Ortega-Deballon P, Guinot PG, Masson D, Gautier T, Bouhemad B
Lien Pubmed
Résumé
The high-density lipoprotein (HDL) and the phospholipid transfer protein (PLTP) have been demonstrated to enhance endotoxin elimination and inactivation in animal models of sepsis. This study aimed to confirm such a role in patients presenting with abdominal sepsis undergoing emergent surgery and explore the relationships between HDL, PLTP and the lipopolysaccharide (LPS) burden (mass and activity).
Mots clés
critical care, endotoxemia, inflammation, lipoproteins, sepsis, septic‐shock
Référence
Eur J Clin Invest. 2025 07 19;:e70099
