Fiche publication
Date publication
août 2025
Journal
BMC biology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MONCHAUD David
Tous les auteurs :
Sharma S, Mitteaux J, Pipier A, Pirrotta M, Penouilh MJ, Monchaud D, Datta B
Lien Pubmed
Résumé
Non-coding RNAs (ncRNAs) in human cells constitute a substantial portion of the transcriptome but do not lead to protein synthesis. Among them, long non-coding RNAs (lncRNAs, > 200 nucleotides long) are fascinating in their ability to orchestrate critical cellular functions that govern cell development, differentiation, and metabolism. Therefore, the dysregulation of lncRNAs has been linked with several diseases, chiefly cancers.
Mots clés
Colorectal cancer, G-quadruplex, Ligands, Long non-coding RNA, Molecular helicases
Référence
BMC Biol. 2025 08 8;23(1):249
