Santo PE, Chagot ME, Gizardin-Fredon H, Ley M, Chenuel T, Deslignière E, Plassart L, Paiva ACF, Sousa PMF, Bertrand E, Charpentier B, Verheggen C, Quinternet M, Meyer P, Bandeiras TM, Cianférani S, Plisson-Chastang C, Manival X

Nat Commun. 2026 02 10;:

The HSP90/R2TP quaternary chaperone scaffolds assembly of the TSC complex.

Abéza C, Busse P, Paiva ACF, Chagot ME, Schneider J, Robert MC, Vandermoere F, Schaeffer C, Charpentier B, M F Sousa P, Bandeiras TM, Manival X, Cianferani S, Bertrand E, Verheggen C

J Mol Biol. 2024 10 26;:168840

Denaturing mass photometry for rapid optimization of chemical protein-protein cross-linking reactions.

Gizardin-Fredon H, Santo PE, Chagot ME, Charpentier B, Bandeiras TM, Manival X, Hernandez-Alba O, Cianférani S

Nat Commun. 2024 04 25;15(1):3516

Coordinated evolution of the SNORD115 and SNORD116 tandem repeats at the imprinted Prader-Willi/Angelman locus.

Guibert M, Marty-Capelle H, Robert A, Charpentier B, Labialle S

NAR Mol Med. 2024 01;1(1):ugad003

Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases.

Dos Santos Morais R, Santo PE, Ley M, Schelcher C, Abel Y, Plassart L, Deslignière E, Chagot ME, Quinternet M, Paiva ACF, Hessmann S, Morellet N, M F Sousa P, Vandermoere F, Bertrand E, Charpentier B, Bandeiras TM, Plisson-Chastang C, Verheggen C, Cianférani S, Manival X

J Mol Biol. 2022 07 25;:167760

The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.

Abel Y, Charron C, Virciglio C, Bourguignon-Igel V, Quinternet M, Chagot ME, Robert MC, Verheggen C, Branlant C, Bertrand E, Manival X, Charpentier B, Rederstorff M

Nucleic Acids Res. 2022 Feb 12;:

Phylogenetic and molecular analyses identify SNORD116 targets involved in the Prader Willi syndrome.

Baldini L, Robert A, Charpentier B, Labialle S

Mol Biol Evol. 2021 Dec 6;:

Emerging Data on the Diversity of Molecular Mechanisms Involving C/D snoRNAs.

Baldini L, Charpentier B, Labialle S

Noncoding RNA. 2021 May 6;7(2):

The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity.

Bragantini B, Charron C, Bourguet M, Paul A, Tiotiu D, Rothé B, Marty H, Terral G, Hessmann S, Decourty L, Chagot ME, Strub JM, Massenet S, Bertrand E, Quinternet M, Saveanu C, Cianférani S, Labialle S, Manival X, Charpentier B

Nat Commun. 2021 03 25;12(1):1859

NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis.

Abel Y, Paiva ACF, Bizarro J, Chagot ME, Santo PE, Robert MC, Quinternet M, Vandermoere F, Sousa PMF, Fort P, Charpentier B, Manival X, Bandeiras TM, Bertrand E, Verheggen C

Nucleic Acids Res. 2020 Dec 24;:

The yeast C/D box snoRNA U14 adopts a "weak" K-turn like conformation recognized by the Snu13 core protein in solution.

Chagot ME, Quinternet M, Rothé B, Charpentier B, Coutant J, Manival X, Lebars I

Biochimie. 2019 Mar 23;:

Bcd1p controls RNA loading of the core protein Nop58 during C/D box snoRNP biogenesis.

Paul A, Tiotiu D, Bragantini B, Marty H, Charpentier B, Massenet S, Labialle S

RNA. 2019 Jan 30;:

Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein.

Fujikane R, Behm-Ansmant I, Tillault AS, Loegler C, Igel-Bourguignon V, Marguet E, Forterre P, Branlant C, Motorin Y, Charpentier B

Sci Rep. 2018 Sep 14;8(1):13815

Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex.

Henri J, Chagot ME, Bourguet M, Abel Y, Terral G, Maurizy C, Aigueperse C, Georgescauld F, Vandermoere F, Saint-Fort R, Behm-Ansmant I, Charpentier B, Pradet-Balade B, Verheggen C, Bertrand E, Meyer P, Cianférani S, Manival X, Quinternet M

Structure. 2018 Jul 18;:

The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones.

Maurizy C, Quinternet M, Abel Y, Verheggen C, Santo PE, Bourguet M, C F Paiva A, Bragantini B, Chagot ME, Robert MC, Abeza C, Fabre P, Fort P, Vandermoere F, M F Sousa P, Rain JC, Charpentier B, Cianférani S, Bandeiras TM, Pradet-Balade B, Manival X, Bertrand E

Nat Commun. 2018 May 29;9(1):2093

NMR assignment and solution structure of the external DII domain of the yeast Rvb2 protein.

Bragantini B, Rouillon C, Charpentier B, Manival X, Quinternet M

Biomol NMR Assign. 2018 Mar 22;:

Implication of the box C/D snoRNP assembly factor Rsa1p in U3 snoRNP assembly.

Rothé B, Manival X, Rolland N, Charron C, Senty-Ségault V, Branlant C, Charpentier B

Nucleic Acids Res.. 2017 May;:

MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes.

Moulin D, Salone V, Koufany M, Clément T, Behm-Ansmant I, Branlant C, Charpentier B, Jouzeau JY

Biomed Res Int. 2017 ;2017:9792512

Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species.

Quinternet M, Chagot ME, Rothé B, Tiotiu D, Charpentier B, Manival X

Structure. 2016 Oct;24(10):1693-1706

Functional and Structural Insights of the Zinc-Finger HIT protein family members Involved in Box C/D snoRNP Biogenesis.

Bragantini B, Tiotiu D, Rothé B, Saliou JM, Marty H, Cianférani S, Charpentier B, Quinternet M, Manival X

J. Mol. Biol.. 2016 Jun;428(11):2488-506

NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins.

Bizarro J, Dodre M, Huttin A, Charpentier B, Schlotter F, Branlant C, Verheggen C, Massenet S, Bertrand E

Nucleic Acids Res. 2015 Aug 14. pii: gkv809.

Structure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP Assembly.

Quinternet M, Rothe B, Barbier M, Bobo C, Saliou JM, Jacquemin C, Back R, Chagot ME, Cianferani S, Meyer P, Branlant C, Charpentier B, Manival X

J Mol Biol. 2015 Aug 28;427(17):2816-39

Contribution of two conserved histidines to the dual activity of archaeal RNA guide-dependent and -independent pseudouridine synthase Cbf5.

Tillault AS, Fourmann JB, Loegler C, Wieden HJ, Kothe U, Charpentier B

RNA. 2015 Jul;21(7):1233-9

(1)H, (15)N and (13)C resonance assignments of the two TPR domains from the human RPAP3 protein.

Chagot ME, Jacquemin C, Branlant C, Charpentier B, Manival X, Quinternet M

Biomol NMR Assign. 2015 Apr;9(1):99-102

(1)H, (15)N and (13)C resonance assignments of the yeast Pih1 and Tah1 C-terminal domains complex.

Manival X, Jacquemin C, Charpentier B, Quinternet M

Biomol NMR Assign. 2015 Apr;9(1):71-3

RNA size is a critical factor for U-containing substrate selectivity and permanent pseudouridylated product release during the RNA:Psi-synthase reaction catalyzed by box H/ACA sRNP enzyme at high temperature.

Tillault AS, Fourmann JB, Loegler C, Blaud M, Branlant C, Charpentier B

Biochimie. 2015 Apr 17. pii: S0300-9084(15)00113-3

Combining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity.

Saliou JM, Manival X, Tillault AS, Atmanene C, Bobo C, Branlant C, Van Dorsselaer A, Charpentier B, Cianferani S

Proteomics. 2015 Feb 27

Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control.

Bizarro J, Charron C, Boulon S, Westman B, Pradet-Balade B, Vandermoere F, Chagot ME, Hallais M, Ahmad Y, Leonhardt H, Lamond A, Manival X, Branlant C, Charpentier B, Verheggen C, Bertrand E

J Cell Biol. 2014 Nov 24;207(4):463-80

Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly.

Rothe B, Back R, Quinternet M, Bizarro J, Robert MC, Blaud M, Romier C, Manival X, Charpentier B, Bertrand E, Branlant C

Nucleic Acids Res. 2014 Feb;42(3):2015-36

Identification of new microRNAs targeting genes regulating the Pi/PPi balance in chondrocytes.

Clement T, Salone V, Charpentier B, Jouzeau JY, Bianchi A

Biomed Mater Eng. 2014;24(1 Suppl):3-16

Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction.

Rothe B, Saliou JM, Quinternet M, Back R, Tiotiu D, Jacquemin C, Loegler C, Schlotter F, Pena V, Eckert K, Morera S, Dorsselaer AV, Branlant C, Massenet S, Sanglier-Cianferani S, Manival X, Charpentier B

Nucleic Acids Res. 2014;42(16):10731-47

High-resolution structural analysis shows how Tah1 tethers Hsp90 to the R2TP complex.

Back R, Dominguez C, Rothe B, Bobo C, Beaufils C, Morera S, Meyer P, Charpentier B, Branlant C, Allain FH, Manival X

Structure. 2013 Oct 8;21(10):1834-47

Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases: relation between conformational dynamics of the guide RNA, enzyme assembly and activity.

Fourmann JB, Tillault AS, Blaud M, Leclerc F, Branlant C, Charpentier B

PLoS One. 2013 Jul 29;8(7):e70313

The sRNA RyhB regulates the synthesis of the Escherichia coli methionine sulfoxide reductase MsrB but not MsrA.

Bos J, Duverger Y, Thouvenot B, Chiaruttini C, Branlant C, Springer M, Charpentier B, Barras F

PLoS One. 2013 May 9;8(5):e63647

Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAs.

Muller S, Leclerc F, Behm-Ansmant I, Fourmann JB, Charpentier B, Branlant C

Nucleic Acids Res. 2008 May;36(8):2459-75

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery.

Boulon S, Marmier-Gourrier N, Pradet-Balade B, Wurth L, Verheggen C, Jady BE, Rothe B, Pescia C, Robert MC, Kiss T, Bardoni B, Krol A, Branlant C, Allmang C, Bertrand E, Charpentier B

J Cell Biol. 2008 Feb 11;180(3):579-95.

A dedicated computational approach for the identification of archaeal H/ACA sRNAs.

Muller S, Charpentier B, Branlant C, Leclerc F

Methods Enzymol. 2007;425:355-87.

Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:Psi-synthase activities.

Muller S, Fourmann JB, Loegler C, Charpentier B, Branlant C

Nucleic Acids Res. 2007;35(16):5610-24

Impact of cyclosporine reduction with MMF: a randomized trial in chronic allograft dysfunction. The 'reference' study.

Frimat L, Cassuto-Viguier E, Charpentier B, Noel C, Provot F, Rostaing L, Glotz D, Sraer JD, Bourbigot B, Moulin B, Lang P, Ducloux D, Pouteil-Noble C, Girardot-Seguin S, Kessler M

Am J Transplant. 2006 Nov;6(11):2725-34.

Tolerability of enteric-coated mycophenolate sodium to 1 year in combination with cyclosporine and corticosteroids in renal transplant recipients.

Rostaing L, Mourad G, Kamar N, Garrigue V, Karras A, Lefrancois N, Charpentier B, Bourbigot B, Pouteil-Noble C, Bayle F, Lebranchu Y, Berthoux F, Le Meur Y, Kessler M, Moulin B, Ducloux D, Delahousse M, Lang P, Merville P, Chaouche-Teyara K, Legendre C

Transplant Proc. 2006 Nov;38(9):2860-3.