Eichler J, Wendling C, Huver S, Zouiouich M, Hanss V, Cardinal A, Fimbel V, Birck C, McEwen AG, Knorr C, Fromental-Ramain C, Boutry M, Chenard MP, Drin G, Tomasetto C, Alpy F

EMBO J. 2026 02 25;:

In vitro methods for studying protein-lipid droplet interactions.

Eichler J, Tomasetto C, Drin G, Alpy F

Methods Enzymol. 2026 02 16;727:93-121

Mammary tumor development induces perturbation of liver glucose metabolism with inflammation and fibrosis.

Charlot A, Bringolf A, Mallard J, Jaulin A, Crouchet E, Charles AL, Duteil D, Alpy F, Tomasetto CL, Baumert TF, Zoll J

Am J Physiol Endocrinol Metab. 2025 03 19;:

Methods for Visualizing and Quantifying Cholesterol Distribution in Mammalian Cells Using Filipin and D4 Probes.

Eichler J, Huver S, Knorr CJ, Wendling C, Kobayashi T, Tomasetto C, Alpy F

Methods Mol Biol. 2025 ;2888:101-118

A genetic screen to uncover mechanisms underlying lipid transfer protein function at membrane contact sites.

Mishra S, Manohar V, Chandel S, Manoj T, Bhattacharya S, Hegde N, Nath VR, Krishnan H, Wendling C, Di Mattia T, Martinet A, Chimata P, Alpy F, Raghu P

Life Sci Alliance. 2024 06;7(6):

MMP-11 expression in early luminal breast cancer: associations with clinical, MRI, pathological characteristics, and disease-free survival.

Molière S, Lodi M, Leblanc S, Gressel A, Mathelin C, Alpy F, Chenard MP, Tomasetto C

BMC Cancer. 2024 03 4;24(1):295

Fast Ultrasound Scanning is a Rapid, Sensitive, Precise and Cost-Effective Method to Monitor Tumor Grafts in Mice.

Molière S, Martinet A, Jaulin A, Lodi M, Chamaraux-Tran TN, Alpy F, Bierry G, Tomasetto C

J Mammary Gland Biol Neoplasia. 2024 01 30;29(1):2

STARD3: A New Biomarker in HER2-Positive Breast Cancer.

Lodi M, Voilquin L, Alpy F, Molière S, Reix N, Mathelin C, Chenard MP, Tomasetto CL

Cancers (Basel). 2023 01 5;15(2):

CLDN1 Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy.

Lemesle M, Geoffroy M, Alpy F, Tomasetto CL, Kuntz S, Grillier-Vuissoz I

Cancers (Basel). 2022 10 14;14(20):

MOSPD2 is an endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis.

Zouiouich M, Di Mattia T, Martinet A, Eichler J, Wendling C, Tomishige N, Grandgirard E, Fuggetta N, Fromental-Ramain C, Mizzon G, Dumesnil C, Carpentier M, Reina-San-Martin B, Mathelin C, Schwab Y, Thiam AR, Kobayashi T, Drin G, Tomasetto C, Alpy F

J Cell Biol. 2022 Jun 6;221(6):

In Situ Artificial Contact Sites (ISACS) between synthetic and endogenous organelle membranes allow for quantification of protein tethering activities.

Milanini J, Magdeleine M, Fuggetta N, Ikhlef S, Brau F, Abelanet S, Alpy F, Tomasetto C, Drin G

J Biol Chem. 2022 Feb 26;:101780

Wnt5a Promotes Lysosomal Cholesterol Egress and Protects Against Atherosclerosis.

Awan S, Lambert M, Imtiaz A, Alpy F, Tomasetto C, Oulad-Abdelghani M, Schaeffer C, Moritz C, Julien-David D, Najib S, Martinez LO, Matz RL, Collet X, Silva-Rojas R, Böhm J, Herz J, Terrand J, Boucher P

Circ Res. 2021 Dec 10;:

FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.

Di Mattia T, Martinet A, Ikhlef S, McEwen AG, Nominé Y, Wendling C, Poussin-Courmontagne P, Voilquin L, Eberling P, Ruffenach F, Cavarelli J, Slee J, Levine TP, Drin G, Tomasetto C, Alpy F

EMBO J. 2020 Oct 30;:e104369

Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR.

Tan B, Jaulin A, Bund C, Outilaft H, Wendling C, Chenard MP, Alpy F, Cicek AE, Namer IJ, Tomasetto C, Dali-Youcef N

Cancers (Basel). 2020 Aug 20;12(9):

The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis.

Carrat GR, Haythorne E, Tomas A, Haataja L, Müller A, Arvan P, Piunti A, Cheng K, Huang M, Pullen TJ, Georgiadou E, Stylianides T, Amirruddin NS, Salem V, Distaso W, Cakebread A, Heesom KJ, Lewis PA, Hodson DJ, Briant LJ, Fung ACH, Sessions RB, Alpy F, Kong APS, Benke PI, Torta F, Keong Teo AK, Leclerc I, Solimena M, Wigley DB, Rutter GA

Mol Metab. 2020 May 13;:101015

Another hijack! Some enteroviruses co-opt the c10orf76/PI4KB complex for their own good.

Voilquin L, Di Mattia T, Alpy F

EMBO Rep.. 2020 Jan 9;:e49876

Faraway, so close! Functions of Endoplasmic reticulum-Endosome contacts.

Di Mattia T, Tomasetto C, Alpy F

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jun 25;:

Intracellular and Plasma Membrane Cholesterol Labeling and Quantification Using Filipin and GFP-D4.

Wilhelm LP, Voilquin L, Kobayashi T, Tomasetto C, Alpy F

Methods Mol. Biol.. 2019 ;1949:137-152

[MOSPD2, an inter-organelle connector].

Di Mattia T, Tomasetto C, Alpy F

Med Sci (Paris). 2019 Jan;35(1):23-25

A novel machine learning-derived decision tree including uPA/PAI-1 for breast cancer care.

Reix N, Lodi M, Jankowski S, Molière S, Luporsi E, Leblanc S, Scheer L, Ibnouhsein I, Benabu JC, Gabriele V, Guggiola A, Lessinger JM, Chenard MP, Alpy F, Bellocq JP, Neuberger K, Tomasetto C, Mathelin C

Clin. Chem. Lab. Med.. 2018 Dec 20;:

Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites.

Di Mattia T, Wilhelm LP, Ikhlef S, Wendling C, Spehner D, Nominé Y, Giordano F, Mathelin C, Drin G, Tomasetto C, Alpy F

EMBO Rep.. 2018 Jun 1;:

STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites.

Wilhelm LP, Wendling C, Védie B, Kobayashi T, Chenard MP, Tomasetto C, Drin G, Alpy F

EMBO J.. 2017 Apr;:

Hemidesmosome integrity protects the colon against colitis and colorectal cancer.

De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyère E, Lefebvre O, Méchine-Neuville A, Siebert S, Pfister V, Lepage P, Laquerriere P, Dembele D, Delanoye-Crespin A, Rodius S, Robine S, Kedinger M, Van Seuningen I, Simon-Assmann P, Chamaillard M, Labouesse M, Georges-Labouesse E

Gut. 2016 Jul;:

Touché! STARD3 and STARD3NL tether the ER to endosomes.

Wilhelm LP, Tomasetto C, Alpy F

Biochem. Soc. Trans.. 2016 Apr;44(2):493-8

Functional relationship between matrix metalloproteinase-11 and matrix metalloproteinase-14.

Buache E, Thai R, Wendling C, Alpy F, Page A, Chenard MP, Dive V, Ruff M, Dejaegere A, Tomasetto C, Rio MC

Cancer Med. 2014 Oct;3(5):1197-210

Stromal matrix metalloproteinase-11 is involved in the mammary gland postnatal development.

Tan J, Buache E, Alpy F, Daguenet E, Tomasetto CL, Ren GS, Rio MC

Oncogene. 2014 Jul 31;33(31):4050-9

START ships lipids across interorganelle space.

Alpy F, Tomasetto C

Biochimie. 2014 Jan;96:85-95

The phosphoinositide-binding protein TRAF4 modulates tight junction stability and migration of cancer cells.

Rousseau A, Wilhelm LP, Tomasetto C, Alpy F

Tissue Barriers. 2014 Aug 8;2(4):e975597

[TRAF4, a multifaceted protein involved in carcinoma progression].

Rousseau A, Tomasetto C, Alpy F

Biol Aujourdhui. 2014;208(4):299-310

STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.

Alpy F, Rousseau A, Schwab Y, Legueux F, Stoll I, Wendling C, Spiegelhalter C, Kessler P, Mathelin C, Rio MC, Levine TP, Tomasetto C

J Cell Sci. 2013 Dec 1;126(Pt 23):5500-12

TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration.

Rousseau A, McEwen AG, Poussin-Courmontagne P, Rognan D, Nomine Y, Rio MC, Tomasetto C, Alpy F

PLoS Biol. 2013 Dec;11(12):e1001726

Perispeckles are major assembly sites for the exon junction core complex.

Daguenet E, Baguet A, Degot S, Schmidt U, Alpy F, Wendling C, Spiegelhalter C, Kessler P, Rio MC, Le Hir H, Bertrand E, Tomasetto C

Mol Biol Cell. 2012 May;23(9):1765-82

In vivo evidence that TRAF4 is required for central nervous system myelin homeostasis.

Blaise S, Kneib M, Rousseau A, Gambino F, Chenard MP, Messadeq N, Muckenstrum M, Alpy F, Tomasetto C, Humeau Y, Rio MC

PLoS One. 2012;7(2):e30917

Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice.

Buache E, Etique N, Alpy F, Stoll I, Muckensturm M, Reina-San-Martin B, Chenard MP, Tomasetto C, Rio MC

Oncogene. 2011 Jul 21;30(29):3261-73

TRAF4, at the Crossroad between Morphogenesis and Cancer.

Rousseau A, Rio MC, Alpy F

Cancers (Basel). 2011 Jun 21;3(2):2734-49

Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation.

Edwards MM, Mammadova-Bach E, Alpy F, Klein A, Hicks WL, Roux M, Simon-Assmann P, Smith RS, Orend G, Wu J, Peachey NS, Naggert JK, Lefebvre O, Nishina PM

J Biol Chem. 2010 Mar 5;285(10):7697-711

Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.

Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, Mercier I, Flomenberg N, Frank PG, Pestell RG, Lisanti MP

Am J Pathol. 2009 May;174(5):1650-62.