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Acceptability and feasibility of a community-hospital parenting support and prevention programme for families of infants at high neurodevelopmental risk following neonatal encephalopathy: protocol of the PRePaR (PRevention and support for Parenthood in ea

Fromion C, Krumm S, Jandet S, Ksiazek E, Gueugnon M, Ornetti P, Meunier-Beillard N, Fournel I

BMJ Open. 2026 03 12;16(3):e110673

Efficacy and safety of a combination of platelet-rich plasma with non-crosslinked hyaluronic acid versus a crosslinked hyaluronic acid, in single-injection for knee osteoarthritis. Randomized, controlled, multicenter, non-inferiority trial.

Riglet L, Delgado T, Lopez RF, Pers YM, Cyteval C, Adam P, Ornetti P

BMC Musculoskelet Disord. 2026 02 25;:

Rehabilitation and return to activity after platelet-rich plasma injections in chronic tendinopathies: Consensus from international experts.

Gremeaux V, Lamontagne M, Bélanger V, Dalmais E, Noël E, Frey A, Ornetti P, Allali F, Gross J, Michel F, Bard H, Kaux JF,

PM R. 2026 01 17;:

Transcutaneous auricular vagus nerve stimulation versus sham stimulation in patients with erosive hand osteoarthritis (ESTIVAL): a randomised, multicentre, double-blind, sham-controlled trial.

Courties A, Tuffet S, Cormier G, Roux CH, Ornetti P, Pers YM, Gottenberg JÉ, Lespessailles E, Chapurlat R, Arniaud D, Rannou F, Wendling D, Eymard F, Mathieu S, Richette P, Saraux A, Marotte H, Poursac N, Rat AC, Bastard JP, Fellahi S, Henrotin Y, Minssen L, Deprouw C, Nguyen C, Touati A, Bérard L, Rousseau A, Simon T, Maheu E, Berenbaum F, Sellam J

Lancet Rheumatol. 2025 12 8;:

Platelet-rich-plasma and knee osteoarthritis: a critical overview of the multiple biases and methodological complexity.

Bard H, Ornetti P, Noël É, Eymard F

Joint Bone Spine. 2025 11 25;:106014

Mature CD209CD83CCR7 dendritic cells infiltrate the arterial wall in giant cell arteritis and derive from in-situ monocyte differentiation.

Ramon A, Greigert H, Lamarthée B, Richard C, Varin A, Cladière C, Genet C, Ciudad M, Klopfenstein N, Praliaud R, Brenac G, Tarris G, Martin L, Arnould L, Gabrielle PH, Garcher CC, Ornetti P, Audia S, Boidot R, Maillefert JF, Bonnotte B, Samson M

Sci Rep. 2025 10 17;15(1):36419

Indications and contraindications to platelet-rich plasma injections in musculoskeletal diseases in case of infectious, oncological and haematological comorbidities: A 2025 formal consensus from the GRIIP (International Research Group on Platelet Injectio

Eymard F, Louati K, Noel É, Abouqal R, Adam P, Allali F, Antherieu G, Caers J, Cognasse F, Collado H, Darrieutort-Laffite C, Frère C, Frey A, Gavillet M, Gremeaux V, Heiblig M, Jerusalem G, Joly C, Kaux JF, Lamontagne M, Leclerc M, Léonard P, Lepeule R, Lopez-Trabada-Ataz D, Magalon J, Michel F, Ornetti P, Oury C, Pons-Tostivint E, Real F, Robert G, Sanchez M, Silvestre A, Bard H

Knee Surg Sports Traumatol Arthrosc. 2025 04 22;:

New guidelines on glucocorticoid-induced adrenal insufficiency: the end of short synacthen test in rheumatology?

Ornetti P, Bouillet B, Denimal D

RMD Open. 2025 01 22;11(1):

Hip disability and Osteoarthritis Outcome Score trajectories and prognostic factors for functional decline: A 3-year follow-up study.

Riglet L, Bourredjem A, Laroche D, Benguella L, Binquet C, Maillefert JF, Ornetti P, Gueugnon M

Ann Phys Rehabil Med. 2024 12 9;68(1):101893

Protocol for a multicentre randomised triple-blind controlled trial assessing the clinical efficacy of intra-articular platelet-rich plasma injections versus placebo in symptomatic knee osteoarthritis (PIKOA).

Eymard F, Oubaya N, Ornetti P, Sellam J, Richette P, Chevalier X,

BMJ Open. 2024 11 29;14(11):e085025

Recommendations from the French Societies of Rheumatology and Physical Medicine and Rehabilitation on the non-pharmacological management of knee osteoarthritis.

Pers YM, Nguyen C, Borie C, Daste C, Kirren Q, Lopez C, Ouvrard G, Ruscher R, Argenson JN, Bardoux S, Baumann L, Berenbaum F, Binard A, Coudeyre E, Czernichow S, Dupeyron A, Fabre MC, Foulquier N, Gérard C, Hausberg V, Henrotin Y, Jeandel C, Lesage FX, Liesse B, Mainard D, Michel F, Ninot G, Ornetti P, Oude-Engberink A, Rat AC, Richette P, Roren A, Thoumie P, Walrand S, Rannou F, Sellam J,

Ann Phys Rehabil Med. 2024 10 26;67(7):101883

Evaluation of the sagittal vertical axis with postural and 3D motion analyses in lumbar spinal stenosis.

Gueugnon M, Riglet L, Fournel I, Ksiazek E, Beaurain J, Chapon R, Ornetti P, Laroche D

BMC Musculoskelet Disord. 2024 10 19;25(1):827

Validity and Test-Retest Reliability of Spatiotemporal Running Parameter Measurement Using Embedded Inertial Measurement Unit Insoles.

Riglet L, Orliac B, Delphin C, Leonard A, Eby N, Ornetti P, Laroche D, Gueugnon M

Sensors (Basel). 2024 08 22;24(16):

Diagnostic accuracy of serum biomarkers to identify giant cell arteritis in patients with polymyalgia rheumatica.

Ramon A, Greigert H, Goueslard K, Cladière C, Ciudad M, Ornetti P, Audia S, Maillefert JF, Bonnotte B, Samson M

RMD Open. 2024 08 8;10(3):

Impact of eccentric cycling in coronary rehabilitation program: a pragmatic randomized controlled trial versus conventional rehabilitation.

Besson D, Sow AK, Fournel I, Gouteron A, Gudjoncik A, Casillas JM, Ornetti P, Laroche D

Eur J Phys Rehabil Med. 2024 07 29;:

3D motion analysis dataset of healthy young adult volunteers walking and running on overground and treadmill.

Riglet L, Delphin C, Claquesin L, Orliac B, Ornetti P, Laroche D, Gueugnon M

Sci Data. 2024 05 30;11(1):556

IMPROVE study protocol, investigating post-stroke local muscle vibrations to promote cerebral plasticity and functional recovery: a single-blind randomised controlled trial.

Julliand S, Papaxanthis C, Delphin C, Mock A, Raumel MA, Gueugnon M, Ornetti P, Laroche D

BMJ Open. 2024 03 15;14(3):e079918

Walking test outcomes in adults with genetic neuromuscular diseases: a systematic literature review of their measurement properties.

Hadouiri N, Fournel I, Thauvin-Robinet C, Jacquin-Piques A, Ornetti P, Gueugnon M

Eur J Phys Rehabil Med. 2024 02 1;:

Influence of posture on gait parameters in severe symptomatic lumbar stenosis before and after decompression surgery.

Chapon R, Alixant P, Laroche D, Ornetti P, Beaurain J, le Van T, Berhouma M, Ricolfi L

World Neurosurg. 2023 11 27;:

Comparison of sacroiliac CT findings in patients with and without ankylosing spondylitis aged over 50 years.

Fakih O, Ramon A, Chouk M, Prati C, Ornetti P, Wendling D, Verhoeven F

Sci Rep. 2023 10 20;13(1):17901

Diagnostic Value of an Additional Sequence (Large-Field Coronal Stir) in a Routine Lumbar Spine MR Imaging Protocol to Investigate Lumbar Radiculopathy.

Patriat Q, Prigent FV, Aho S, Lenfant M, Ramon A, Loffroy R, Lambert A, Ornetti P

J Clin Med. 2023 09 28;12(19):

The Use of Embedded IMU Insoles to Assess Gait Parameters: A Validation and Test-Retest Reliability Study.

Riglet L, Nicol F, Leonard A, Eby N, Claquesin L, Orliac B, Ornetti P, Laroche D, Gueugnon M

Sensors (Basel). 2023 09 28;23(19):

Uncommon acrometastasis mimicking dactylitis.

Herrmann S, Laboz M, Ornetti P

Joint Bone Spine. 2023 09 19;:105638

Time to return to work after total trapeziometacarpal prosthesis.

Tchurukdichian A, Delgove A, Essid L, Moris V, di Summa PG, Camuzard O, Ornetti P, Zwetyenga N, Guillier D

Hand Surg Rehabil. 2023 06 23;:

Comparison of sacroiliac CT findings in patients with and without psoriatic arthritis: results of the CASIPSA Study.

Fakih O, Ramon A, Chouk M, Prati C, Ornetti P, Wendling D, Verhoeven F

Rheumatology (Oxford). 2023 05 30;:

Predictive Factors of Giant Cell Arteritis in Polymyalgia Rheumatica Patients.

Ramon A, Greigert H, Ornetti P, Maillefert JF, Bonnotte B, Samson M

J Clin Med. 2022 12 14;11(24):

Functional recovery after total hip/knee replacement in obese people: A systematic review.

Courtine M, Bourredjem A, Gouteron A, Fournel I, Bartolone P, Baulot E, Ornetti P, Martz P

Ann Phys Rehabil Med. 2022 11 29;66(1):101710

Gait analysis dataset of healthy volunteers and patients before and 6 months after total hip arthroplasty.

Bertaux A, Gueugnon M, Moissenet F, Orliac B, Martz P, Maillefert JF, Ornetti P, Laroche D

Sci Data. 2022 07 12;9(1):399

Iliac periostitis revealing acute leukemia.

Lambert A, Ramon A, Jacob D, Ornetti P

Joint Bone Spine. 2022 Feb 3;:105351

Mimickers of Large Vessel Giant Cell Arteritis.

Ramon A, Greigert H, Ornetti P, Bonnotte B, Samson M

J Clin Med. 2022 Jan 19;11(3):

Optimization of dual energy computed tomography post-processing to reduce lower limb artifacts in gout.

Dubief B, Avril J, Pascart T, Schmitt M, Loffroy R, Maillefert JF, Ornetti P, Ramon A

Quant Imaging Med Surg. 2022 Jan;12(1):539-549

Intra-articular injections of platelet-rich plasma in symptomatic knee osteoarthritis: a consensus statement from French-speaking experts.

Eymard F, Ornetti P, Maillet J, Noel É, Adam P, Legré-Boyer V, Boyer T, Allali F, Gremeaux V, Kaux JF, Louati K, Lamontagne M, Michel F, Richette P, Bard H,

Knee Surg Sports Traumatol Arthrosc. 2021 Oct;29(10):3195-3210

Homozygous TRAPPC11 truncating variant revealing segmental uniparental disomy of chromosome 4 as a cause of a recessive limb-girdle muscular dystrophy-18.

Hadouiri N, Thomas Q, Darmency V, Dulieu V, De Rougemont MM, Bruel AL, Duffourd Y, Lecoquierre F, Colomb B, Perez-Martin S, Ornetti P, Blanchard O, Sorlin A, Philippe C, Faivre L, Vitobello A, Thauvin-Robinet C

Clin Genet. 2021 Aug 25;:

Dynamic global sagittal alignment in patients with lumbar spinal stenosis: Analysis of the effects of decompression surgery on gait adaptations.

Lamas V, Gueugnon M, Fournel I, Grelat M, Maillefert JF, Ornetti P, Martz P

Gait Posture. 2021 07;88:272-279

Perforating Rheumatoid Nodule Mimicking Malignant Soft-tissue Mass of the Forearm.

Ornetti P, Guillier D, Jeudy G

J Rheumatol. 2021 07;48(7):1103

Mucosal-associated invariant T cells in Giant Cell Arteritis.

Ghesquière T, Ciudad M, Ramon A, Greigert H, Gerard C, Cladière C, Thébault M, Genet C, Devilliers H, Maurier F, Ornetti P, Quipourt V, Gabrielle PH, Creuzot-Garcher C, Tarris G, Martin L, Soudry-Faure A, Saas P, Audia S, Bonnotte B, Samson M

J Autoimmun. 2021 May 14;121:102652

Is the Short and Fast Step Test a safe and feasible tool for exploring anaerobic capacities of individuals with coronary heart disease in clinical practice?

Besson D, Gouteron A, Hannequin A, Casillas JM, Rigaud L, Ornetti P, Fournel I, Ksiazek E, Laroche D, Gueugnon M

Eur J Phys Rehabil Med. 2021 Feb 23;:

Validation of a Dutch diagnostic rule for gout without joint fluid analysis in patients hospitalized for acute monoarthritis.

Schmitt M, Ramon A, Ornetti P, Maillefert JF

Rheumatology (Oxford). 2021 02 1;60(2):979-981

Effectiveness, safety, and cost-utility of a knee brace in medial knee osteoarthritis: the ERGONOMIE randomized controlled trial.

Gueugnon M, Fournel I, Soilly AL, Diaz A, Baulot E, Bussière C, Casillas JM, Cherasse A, Conrozier T, Loeuille D, Maillefert JF, Mazalovic K, Timsit M, Wendling D, Ramon A, Binquet C, Morisset C, Ornetti P

Osteoarthritis Cartilage. 2021 Jan 29;:

Performance of ultrasound to assess erosion progression in rheumatoid arthritis.

Peran M, Allado E, Albuisson E, Couderc M, Ornetti P, Roux C, Grosse J, Chary-Valckenaere I, Loeuille D

Eur J Radiol. 2021 Jan 12;136:109536

The frequency of occult solid malignancy in patients with polymyalgia rheumatica-like symptoms.

Ramon A, Guillibert-Karras C, Milas-Julien L, Garrot JF, Maillefert JF, Ornetti P

Ther Adv Musculoskelet Dis. 2021 ;13:1759720X20984275

Diagnostic performance of sacroiliac and spinal MRI for the diagnosis of non-radiographic axial spondyloarthritis in patients with inflammatory back pain.

Herrada I, Devilliers H, Fayolle C, Attané G, Loffroy R, Verhoeven F, Ornetti P, Ramon A

Joint Bone Spine. 2020 Nov 10;:105106

Machine Learning Approaches for Activity Recognition and/or Activity Prediction in Locomotion Assistive Devices-A Systematic Review.

Labarrière F, Thomas E, Calistri L, Optasanu V, Gueugnon M, Ornetti P, Laroche D

Sensors (Basel). 2020 Nov 6;20(21):

Efficacy of tocilizumab in patients with hand osteoarthritis: double blind, randomised, placebo-controlled, multicentre trial.

Richette P, Latourte A, Sellam J, Wendling D, Piperno M, Goupille P, Pers YM, Eymard F, Ottaviani S, Ornetti P, Flipo RM, Fautrel B, Peyr O, Bertola JP, Vicaut E, Chevalier X

Ann Rheum Dis. 2020 Oct 14;:

Recommendations of the French Society of Rheumatology on pharmacological treatment of knee osteoarthritis.

Sellam J, Courties A, Eymard F, Ferrero S, Latourte A, Ornetti P, Bannwarth B, Baumann L, Berenbaum F, Chevalier X, Ea HK, Fabre MC, Forestier R, Grange L, Lellouche H, Maillet J, Mainard D, Perrot S, Rannou F, Rat AC, Roux CH, Senbel E, Richette P,

Joint Bone Spine. 2020 Sep 12;:

Dual energy computed tomography: A breakthrough for gout?

Ramon A, Ornetti P

Joint Bone Spine. 2020 07;87(4):289-291

Association of Specific Comorbidities with Monosodium Urate Crystal Deposition in Urate-Lowering Therapy-Naive Gout Patients: A Cross-Sectional Dual-Energy Computed Tomography Study.

Pascart T, Ramon A, Ottaviani S, Legrand J, Ducoulombier V, Houvenagel E, Norberciak L, Richette P, Becce F, Ornetti P, Budzik JF

J Clin Med. 2020 May 1;9(5):

Progressively increasing the intensity of eccentric cycling over four training sessions: A feasibility study in coronary heart disease patients.

Pageaux B, Besson D, Casillas JM, Lepers R, Gremeaux V, Ornetti P, Gouteron A, Laroche D

Ann Phys Rehabil Med. 2019 Oct 24;:

Influence of body mass index on sagittal hip range of motion and gait speed recovery six months after total hip arthroplasty.

Martz P, Bourredjem A, Maillefert JF, Binquet C, Baulot E, Ornetti P, Laroche D

Int Orthop. 2019 Jan 5;:

Age-Related Adaptations of Lower Limb Intersegmental Coordination During Walking.

Gueugnon M, Stapley PJ, Gouteron A, Lecland C, Morisset C, Casillas JM, Ornetti P, Laroche D

Front Bioeng Biotechnol. 2019 ;7:173

Is the Pelvis-Thorax Coordination a Valuable Outcome Instrument to Assess Patients With Hip Osteoarthritis?

Moissenet F, Naaim A, Ornetti P, Bourredjem A, Binquet C, Morisset C, Gouteron A, Maillefert JF, Laroche D

Front Bioeng Biotechnol. 2019 ;7:457

Gout misdiagnosis due to dual-energy computed tomography artefact.

Ramon A, Pottecher P, Ornetti P

Rheumatology (Oxford). 2018 Jul 1;57(7):1234

Paraparesis Revealing Tophaceous Gout.

Pottecher P, Martz P, Ornetti P

Arthritis Rheumatol. 2018 06;70(6):942

Vitamin D supplementation, bone turnover, and inflammation in HIV-infected patients.

Benguella L, Arbault A, Fillion A, Blot M, Piroth C, Denimal D, Duvillard L, Ornetti P, Chavanet P, Maillefert JF, Piroth L

Med Mal Infect. 2018 Apr 13;:

CT analysis of the aorta in giant-cell arteritis: a case-control study.

Berthod PE, Aho-Glélé S, Ornetti P, Chevallier O, Devilliers H, Ricolfi F, Bonnotte B, Loffroy R, Samson M

Eur Radiol. 2018 Mar 29;:

Role of dual-energy CT in the diagnosis and follow-up of gout: systematic analysis of the literature.

Ramon A, Bohm-Sigrand A, Pottecher P, Richette P, Maillefert JF, Devilliers H, Ornetti P

Clin. Rheumatol.. 2018 Mar;37(3):587-595

Burned to the Bone.

Bohm-Sigrand A, Pottecher P, Ornetti P

J Rheumatol. 2017 Oct;44(10):1507-1508

Osteitis fibrosa cystica.

Arbault A, Ornetti P, Laroche D, Pottecher P

Joint Bone Spine. 2017 03;84(2):229

Röttinger approach with dual-mobility cup to improve functional recovery in hip osteoarthritis patients: biomechanical and clinical follow-up.

Martz P, Bourredjem A, Laroche D, Arcens M, Labattut L, Binquet C, Maillefert JF, Baulot E, Ornetti P

Int Orthop. 2017 Mar;41(3):461-467

Giant subperiosteal hematoma.

Ornetti P, Loffroy R, Grimault L, Chevallier O, Pottecher P

Quant Imaging Med Surg. 2016 Dec;6(6):791-792

Reliability, validity and feasibility of nail ultrasonography in psoriatic arthritis.

Arbault A, Devilliers H, Laroche D, Cayot A, Vabres P, Maillefert JF, Ornetti P

Joint Bone Spine. 2016 Oct;83(5):539-44

Involvement and prognosis value of CD8(+) T cells in giant cell arteritis.

Samson M, Ly KH, Tournier B, Janikashvili N, Trad M, Ciudad M, Gautheron A, Devilliers H, Quipourt V, Maurier F, Meaux-Ruault N, Magy-Bertrand N, Manckoundia P, Ornetti P, Maillefert JF, Besancenot JF, Ferrand C, Mesturoux L, Labrousse F, Fauchais AL, Saas P, Martin L, Audia S, Bonnotte B

J. Autoimmun.. 2016 Aug;72:73-83

Parascapular mass revealing primary tuberculosis of the posterior arch.

Arbault A, Ornetti P, Loffroy R, Chevallier O, Avril J, Pottecher P

Quant Imaging Med Surg. 2016 Aug;6(4):454-456

Impact of systematic ultrasound of the knee on the rheumatologist's clinical decision in patients consulting for knee pain.

Couturier M, Arbault A, Laroche D, Contant E, Lambert A, Pottecher P, Ornetti P

Rheumatol Int. 2016 Feb;36(2):283-8

Does platelet-rich plasma have a role in the treatment of osteoarthritis?

Ornetti P, Nourissat G, Berenbaum F, Sellam J, Richette P, Chevalier X,

Joint Bone Spine. 2016 Jan;83(1):31-6

Axonotmesis of the femoral and sciatic nerves mimicking lumbar radiculopathy.

Arbault A, Ornetti P, Genson PY, Loffroy R, Pottecher P

Quant Imaging Med Surg. 2015 Dec;5(6):932-3

Test-retest reliability and responsiveness of centre of pressure measurements in patients with hip osteoarthritis.

Laroche D, Kubicki A, Stapley PJ, Gremeaux V, Mazalovic K, Maillefert JF, Ornetti P

Osteoarthritis Cartilage. 2015 Aug;23(8):1357-66

Does platelet-rich plasma deserve a role in the treatment of tendinopathy?

Nourissat G, Ornetti P, Berenbaum F, Sellam J, Richette P, Chevalier X

Joint Bone Spine. 2015 Jul;82(4):230-4

Clinical effectiveness and safety of a distraction-rotation knee brace for medial knee osteoarthritis.

Ornetti P, Fortunet C, Morisset C, Gremeaux V, Maillefert JF, Casillas JM, Laroche D

Ann Phys Rehabil Med. 2015 Jun;58(3):126-31

Impact of repeated measures of joint space width on the sample size calculation: An application to hip osteoarthritis.

Ornetti P, Gossec L, Laroche D, Combescure C, Dougados M, Maillefert JF

Joint Bone Spine. 2015 May;82(3):172-6

Hyaluronan for knee osteoarthritis: an updated meta-analysis of trials with low risk of bias.

Richette P, Chevalier X, Ea HK, Eymard F, Henrotin Y, Ornetti P, Sellam J, Cucherat M, Marty M

RMD Open. 2015 ;1(1):e000071

A classification study of kinematic gait trajectories in hip osteoarthritis.

Laroche D, Tolambiya A, Morisset C, Maillefert JF, French RM, Ornetti P, Thomas E

Comput. Biol. Med.. 2014 Dec;55:42-8

Cytochrome P450 interactions and clinical implication in rheumatology.

Cayot A, Laroche D, Disson-Dautriche A, Arbault A, Maillefert JF, Ornetti P

Clin Rheumatol. 2014 Sep;33(9):1231-8

Does tocilizumab indeed reduce the frequency of Th17 cells? Comment on the article by Thiolat et al.

Samson M, Audia S, Ornetti P, Maillefert JF, Janikashvili N, Bonnotte B

Arthritis Rheumatol. 2014 Sep;66(9):2639-40

SAPHO syndrome revealed by sclerosing mandibular osteomyelitis.

Pottecher P, Loffroy R, Estivalet L, Thouant P, Ornetti P, Ricolfi F, Krausé D

Diagn Interv Imaging. 2014 Sep;95(9):885-7

Biomechanical effectiveness of a distraction-rotation knee brace in medial knee osteoarthritis: preliminary results.

Laroche D, Morisset C, Fortunet C, Gremeaux V, Maillefert JF, Ornetti P

Knee. 2014 Jun;21(3):710-6

Cross-talk correction method for knee kinematics in gait analysis using principal component analysis (PCA): a new proposal.

Baudet A, Morisset C, d'Athis P, Maillefert JF, Casillas JM, Ornetti P, Laroche D

PLoS ONE. 2014 ;9(7):e102098

Severe hypovitaminosis D correlates with increased inflammatory markers in HIV infected patients.

Ansemant T, Mahy S, Piroth C, Ornetti P, Ewing S, Guilland JC, Croisier D, Duvillard L, Chavanet P, Maillefert JF, Piroth L

BMC Infect. Dis.. 2013 Jan;13:7

Th1 and Th17 lymphocytes expressing CD161 are implicated in giant cell arteritis and polymyalgia rheumatica pathogenesis.

Samson M, Audia S, Fraszczak J, Trad M, Ornetti P, Lakomy D, Ciudad M, Leguy V, Berthier S, Vinit J, Manckoundia P, Maillefert JF, Besancenot JF, Aho-Glele S, Olsson NO, Lorcerie B, Guillevin L, Mouthon L, Saas P, Bateman A, Martin L, Janikashvili N, Larmonier N, Bonnotte B

Arthritis Rheum. 2012 Nov;64(11):3788-98