Witz A, Conroy T, Lambert A, Salleron J, Diallo A, Husson M, Nicolle R, Hammel P, Biagi J, Renouf DJ, Turpin A, Richard C, Bachet JB, Iovanna J, Dusetti N, Monard L, Mauduit M, Cros J, Harlé A

J Clin Oncol. 2026 08 3;:JCO2502508

Developing a Histology-Based Artificial Intelligence Biomarker to Predict Adjuvant Chemotherapy Benefit in Pancreatic Cancer.

Beaufils A, De Martino J, Jiang X, Blanchard T, Fraunhoffer N, Mendes D, Pignolet C, Bourega T, Meneghetti AR, Sainath S, Albuquerque M, Colnot N, Tihy M, Turpin A, Ben Abdelghani M, Wei A, Mitry E, Lecomte T, Biagi J, Artru P, Evesque L, Lambert A, Renouf DJ, Mauduit M, Dusetti NJ, Hammel P, Conroy T, Bachet JB, de Mestier L, Rebours V, Cros J, Kather JN, Nicolle R

J Clin Oncol. 2026 07 27;:JCO2600327

Antiangiogenic therapies in gastric cancer: future directions for 2026 and beyond: an UNICANCER gastrointestinal group (UCGI) perspective.

Raimbourg J, Abdelghani MB, Boige V, Botsen D, Carnot A, Coutzac C, Delaye M, De Sousa Carvalho N, Dos Santos M, Edeline J, Ghiringhelli F, Lambert A, Le Sourd S, Palmieri LJ, Pernot S, Samalin E, Smolenschi C, Vivier-Chicoteau J, Marion S, de la Fouchardière C

Cancer Treat Rev. 2026 06 24;148:103177

SPINAL: study protocol for a multicenter non-inferiority trial evaluating reduce vertebral irradiation volumes in palliative radiotherapy for spinal bone metastases on analgesic efficacy.

Faivre JC, Lambert A, Bruand M, Francais A, Supiot S, Thureau S, Bourbonne V, Tomaszewski F, Charra-Brunaud C, Py JF, Stefani A, Jolnerovski M, Demogeot N, Cuenin M, Renard S, Sellami S, Trampetti I, Bernier-Chastagner V, Jacques J, Agnoux E, Appavou RA, Gehin W, Martz N, Mammari N

BMC Cancer. 2026 04 24;:

Beyond Mankind, Self-Illusion and Medical Expertise of Artificial Intelligence in the Era of COVID-19.

Claessens A, Claessens YE, Lambert A, Gehin W

Open Forum Infect Dis. 2026 04;13(4):ofag188

AI-Driven Patient Screening for Clinical Trials in Pancreatic Cancer: The PANCR-AI Pilot Retrospective Comparative Study.

Claessens A, Simon A, Manchart A, Desmonts L, Leguay C, Faivre JC, Cambier S, Salleron J, Lambert A

JMIR Cancer. 2026 02 23;12:e80268

Sarcopenia Predicts Mortality in Bladder Cancer with Neoadjuvant Chemotherapy: A Multicenter Study.

Pitout A, Mazeaud C, Blondeau A, Salleron J, Massard V, Lambert A

Cancers (Basel). 2026 01 11;18(2):

Lung-only metastatic pancreatic cancer: Differences in patients 'characteristics, molecular profile and survival.

Boilève A, Mercier L, Bonnet B, Tarabay A, Blanchet-Deverly S, Hollebecque A, Smolenschi C, Valéry M, Delaye M, Pudlarz T, Fuerea A, Boige V, Durand-Labrunie J, Gelli M, Beunon P, Barbe R, Lambert A, Ducreux M

Eur J Cancer. 2026 01 9;235:116227

Sensitive cell-free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study.

Harlé A, Gavoille C, Bouché O, Abdelghani MB, Plaza J, Spaeth D, Boudrant A, Ghiringhelli F, Villing AL, Borg C, Rouyer M, Husson M, Gilson P, Salleron J, Lambert A, Merlin JL

Oncol Lett. 2026 01;31(1):13

HPV circulating tumor DNA to monitor response to pembrolizumab and vorinostat combination in patients with advanced HPV-related squamous-cell carcinomas.

Filippini DM, Cabarrou B, Dupain C, Halladjian M, Coquan E, Sablin MP, Mazzarella L, Francisco M, Servant N, Tonini MM, Hundt AF, Castel-Ajgal Z, You B, Bigot F, Ghiringhelli F, Vansteene D, Gomez-Roca C, Cousin S, Lambert A, Saada-Bouzid E, Durando X, Abdeddaim C, Borel C, Chaltiel R, Borcoman E, Legrand F, Bernhart S, Jimenez M, Bièche I, Filleron T, Le Tourneau C, Kamal M, Jeannot E

ESMO Open. 2025 12 29;11(1):106024

Sarcopenia measured by artificial intelligence as a predictor of overall survival in localized bladder cancer, a multicenter study.

Blondeau A, Pitout A, Manuguerra A, Eschwege P, Mazeaud C, Lambert A

BMC Cancer. 2025 12 11;:

Radiotherapy in the management of PDAC, from past to present.

Dardare J, Martz N, Witz A, Betz M, Michel C, Gilson P, Merlin JL, Lambert A, Harle A

Transl Oncol. 2025 12 8;63:102632

Combining radiotherapy and immune checkpoint inhibitors in metastatic cancers: a 25-year review of safety outcomes by the ENRSO Group.

Golfier C, Visy A, Gueiderikh A, Marcel J, Escande A, Scala-Bertola J, Metzger M, Lambert A, Faivre JC

Cancer Metastasis Rev. 2025 11 14;44(4):83

CD40 agonist mitazalimab with mFOLFIRINOX in untreated metastatic pancreatic cancer: Biomarkers associated with outcomes from OPTIMIZE-1.

Van Laethem JL, Geboes K, Borbath I, Macarulla Mercade T, Lambert A, Cassier P, Prenen H, Mitry E, Blanc JF, Pilla L, Feliu J, Rodriguez Garrote M, Pazo-Cid RA, Gallego I, Smith KE, Nordbladh K, Jimenez DG, Ellmark P, Pico de Coaña Y, Ambarkhane SV, Beatty GL, O'Reilly EM

Cell Rep Med. 2025 10 7;:102407

Improving Radiation Therapy in Pancreatic Cancer Through Radiosensitization Strategies.

Dardare J, Martz N, Witz A, Betz M, Michel C, Gilson P, Merlin JL, Lambert A, Harle A

Int J Radiat Oncol Biol Phys. 2025 09 16;:

Efficacy of pembrolizumab and vorinostat combination in patients with recurrent and/or metastatic squamous cell carcinomas: a phase 2 basket trial.

Borcoman E, Cabarrou B, Francisco M, Bigot F, Ghiringhelli F, Vansteene D, Legrand F, Halladjian M, Dupain C, Le Saux O, Coutzac C, Borel C, Chaltiel R, You B, Gomez-Roca C, Cousin S, Coquan E, Lambert A, Saada-Bouzid E, Durando X, Saint-Ghislain M, Frige G, Guerini-Rocco E, Tonini MM, Bièche I, Castel-Ajgal Z, Marret G, Sablin MP, Jeannot E, Andre F, Filleron T, Jimenez M, Mazzarella L, Servant N, Kamal M, Le Tourneau C

Nat Cancer. 2025 06 30;:

AI-based CT assessment of sarcopenia in borderline resectable pancreatic Cancer: A narrative review of clinical and technical perspectives.

Gehin W, Lambert A, Bibault JE

Comput Biol Med. 2025 06 25;195:110659

First-Line Therapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Retrospective, Multicenter, Real-World Study.

Simon A, Abdeddaim C, Nguyen D, Gallet P, Peiffert D, Lambert A, Geoffrois L

Head Neck. 2025 06 10;:

Neuron-Specific Enolase as a Biomarker in Ifosfamide-Induced Encephalopathy: A Case Report.

Claessens A, Manchart A, Boufraine M, Guignard A, Bergeot A, Kieffer A, Lambert A

Case Rep Oncol. 2025 05 28;18(1):800-808

Impact of Electronic Transition and Prefilled Templates on Drug Prescription Compliance: Retrospective Study.

Lambert A, Hombourger B, Salleron J, Chergui F, Vallance C, Nicolas N, Moussouni M, Cherif L, Chenot E, Gavoille C, Massard V

J Med Internet Res. 2025 04 9;27:e57782

[Living with… pancreatic cancer].

Baudry S, Duval F, Lambert A

Rev Prat. 2025 01;75(1):72-74

KRAS, a New Target for Precision Medicine in Colorectal Cancer?

Boilève A, Smolenschi C, Lambert A, Boige V, Delaye M, Camilleri GM, Tarabay A, Valéry M, Fuerea A, Pudlarz T, Mathieu JRR, Jaulin F, Hollebecque A, Ducreux M

Cancers (Basel). 2024 10 12;16(20):

DDB2 expression lights the way for precision radiotherapy response in PDAC cells, with or without olaparib.

Dardare J, Witz A, Betz M, François A, Lamy L, Husson M, Demange J, Rouyer M, Lambert A, Merlin JL, Gilson P, Harlé A

Cell Death Discov. 2024 09 27;10(1):411

Impact of Positive Resection Margins on Recurrence and Survival Following Resection and Adjuvant Chemotherapy in Pancreatic Cancer: Results of the PRODIGE 24-CCTG PA-6 Randomized Controlled Trial.

Lambert A, Salleron J, Harlé A, Biagi JJ, Leroux A, Thomas J, Monard L, Cros J, Marchal F, Ayav A, Conroy T

Ann Surg. 2024 07 23;:

Role of molecular biology in the management of pancreatic cancer.

Boileve A, Smolenschi C, Lambert A, Boige V, Tarabay A, Valery M, Fuerea A, Pudlarz T, Conroy T, Hollebecque A, Ducreux M

World J Gastrointest Oncol. 2024 07 15;16(7):2902-2914

Factors Associated with Myocardial Uptake on Oncologic Somatostatin PET Investigations and Differentiation from Myocardial Uptake of Acute Myocarditis.

Larive T, Boursier C, Claudin M, Varlot J, Filippetti L, Huttin O, Roch V, Imbert L, Doyen M, Lambert A, Mandry D, Lamiral Z, Chevalier E, Marie PY

J Nucl Med. 2024 07 11;:

Development and validation of AI-assisted transcriptomic signatures to personalize adjuvant chemotherapy in patients with pancreatic ductal adenocarcinoma.

Fraunhoffer N, Hammel P, Conroy T, Nicolle R, Bachet JB, Harlé A, Rebours V, Turpin A, Abdelghani MB, Mitry E, Biagi J, Chanez B, Bigonnet M, Lopez A, Evesque L, Lecomte T, Assenat E, Bouché O, Renouf D, Lambert A, Monard L, Mauduit M, Cros J, Iovanna J, Dusetti N

Ann Oncol. 2024 06 19;:

Combining CD40 agonist mitazalimab with mFOLFIRINOX in previously untreated metastatic pancreatic ductal adenocarcinoma (OPTIMIZE-1): a single-arm, multicentre phase 1b/2 study.

Van Laethem JL, Borbath I, Prenen H, Geboes KP, Lambert A, Mitry E, Cassier PA, Blanc JF, Pilla L, Batlle JF, Garrote MR, Pazo-Cid RA, Gallego I, Smith KE, Ellmark P, Pico de Coaña Y, Ambarkhane SV, Macarulla T

Lancet Oncol. 2024 05 31;:

Association Between Baseline Hemodynamic Indices, Cardiotoxicity Risk and Survival in Women with Breast Cancer.

Decorads CE, Lambert A, Roch V, Imbert L, Perrin M, Claudin M, Doyen M, Citerne Q, Lamiral Z, Peiffert D, Henneton C, Marie PY

J Nucl Cardiol. 2024 03 18;:101849

[Development of an artificial intelligence system to improve cancer clinical trial eligibility screening].

Gédor M, Desandes E, Chesnel M, Merlin JL, Marchal F, Lambert A, Baudin A

Bull Cancer. 2024 03 18;:

Digital Life Stories of People With Cancer: Impacts on Research

S. Rossi, F. Claudot, A. Lambert, and J. Kivits

Int J Qual Methods. 2024 ;23(1-12):

Prediction of Adjuvant Gemcitabine Sensitivity in Resectable Pancreatic Adenocarcinoma Using the GemPred RNA Signature: An Ancillary Study of the PRODIGE-24/CCTG PA6 Clinical Trial.

Nicolle R, Bachet JB, Harlé A, Iovanna J, Hammel P, Rebours V, Turpin A, Ben Abdelghani M, Wei A, Mitry E, Lopez A, Biagi J, François E, Artru P, Lambert A, Renouf DJ, Monard L, Mauduit M, Dusetti N, Conroy T, Cros J

J Clin Oncol. 2023 11 14;:JCO2202668

COVID-19 Infection despite Previous Vaccination in Cancer Patients and Healthcare Workers: Results from a French Prospective Multicenter Cohort (PAPESCO-19).

Seegers V, Rousseau G, Zhou K, Blanc-Lapierre A, Bigot F, Mahammedi H, Lambert A, Moreau-Bachelard C, Campone M, Conroy T, Penault-Llorca F, Bellanger MM, Raoul JL

Cancers (Basel). 2023 09 28;15(19):

Diagnostic Value of an Additional Sequence (Large-Field Coronal Stir) in a Routine Lumbar Spine MR Imaging Protocol to Investigate Lumbar Radiculopathy.

Patriat Q, Prigent FV, Aho S, Lenfant M, Ramon A, Loffroy R, Lambert A, Ornetti P

J Clin Med. 2023 09 28;12(19):

Adjuvant and neoadjuvant approaches in pancreatic cancer.

Conroy T, Lambert A, Ducreux M

Curr Opin Oncol. 2023 05 15;:

DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy.

Dardare J, Witz A, Betz M, Francois A, Meras M, Lamy L, Lambert A, Grandemange S, Husson M, Rouyer M, Demange J, Merlin JL, Harlé A, Gilson P

Front Oncol. 2022 12 8;12:1052163

Incidence and associated factors of cetuximab-induced hypersensitivity infusion reactions in 1392 cancer patients treated in four French areas: a possible association with Lyme disease?

Dupont M, Carlier C, Gower-Rousseau C, Barbier-Lider P, Botsen D, Brasseur M, Burgevin A, Chourbagi C, D'Almeida R, Hautefeuille V, Hentzien M, Lambert A, Lamuraglia M, Lavau-Denes S, Lopez A, Parent D, Slimano F, Brugel M, Bouché O

BMC Cancer. 2022 11 25;22(1):1219

COVID-19 Vaccination Campaign in Cancer Patients and Healthcare Workers-Results from a French Prospective Multicenter Cohort (PAPESCO-19).

Seegers V, Rousseau G, Zhou K, Blanc-Lapierre A, Bigot F, Mahammedi H, Lambert A, Moreau-Bachelard C, Campone M, Conroy T, Penault-Llorca F, Boisdron-Celle M, Bellanger M, Raoul JL

Cancers (Basel). 2022 11 11;14(22):

Routine first-line detection of breast cancer therapy-related cardiotoxicity by serial, fast and ultra-low-dose equilibrium radionuclide angiography.

Decorads CE, Lambert A, Roch V, Imbert L, Perrin M, Claudin M, Salleron J, Veran N, Lamiral Z, Henneton C, Marie PY

J Nucl Cardiol. 2022 10 26;:

Development of a Clinical-Biological Model to Assess Tumor Progression in Metastatic Pancreatic Cancer: Post Hoc Analysis of the PRODIGE4/ACCORD11 Trial.

Egea J, Salleron J, Gourgou S, Ayav A, Laurent V, Juzyna B, Harlé A, Conroy T, Lambert A

Cancers (Basel). 2022 10 16;14(20):

Five-Year Outcomes of FOLFIRINOX vs Gemcitabine as Adjuvant Therapy for Pancreatic Cancer: A Randomized Clinical Trial.

Conroy T, Castan F, Lopez A, Turpin A, Ben Abdelghani M, Wei AC, Mitry E, Biagi JJ, Evesque L, Artru P, Lecomte T, Assenat E, Bauguion L, Ychou M, Bouché O, Monard L, Lambert A, Hammel P,

JAMA Oncol. 2022 09 1;:

Preneoplastic Lesions in Surgical Specimens Do Not Worsen the Prognosis of Patients Who Underwent Surgery for Pancreatic Adenocarcinoma: Post-Hoc Analysis of the PRODIGE 24-CCTG PA 6 Trial.

Legrand T, Salleron J, Conroy T, Marchal F, Thomas J, Monard L, Biagi JJ, Lambert A

Cancers (Basel). 2022 08 16;14(16):

Assessment of performances of a deep learning algorithm for the detection of limbs and pelvic fractures, dislocations, focal bone lesions, and elbow effusions on trauma X-rays.

Regnard NE, Lanseur B, Ventre J, Ducarouge A, Clovis L, Lassalle L, Lacave E, Grandjean A, Lambert A, Dallaudière B, Feydy A

Eur J Radiol. 2022 07 22;154:110447

FOLFIRI plus BEvacizumab or aFLIbercept after FOLFOX-bevacizumab failure for COlorectal cancer (BEFLICO): An AGEO multicenter study.

Torregrosa C, Pernot S, Vaflard P, Perret A, Tournigand C, Randrian V, Doat S, Neuzillet C, Moulin V, Stouvenot M, Roth G, Darbas T, Auberger B, Godet T, Jaffrelot M, Lambert A, Dubreuil O, Gluszak C, Bernard-Tessier A, Turpin A, Palmieri LJ, Bouche O, Goujon G, Lecomte T, Sefrioui D, Locher C, Grados L, Gignoux P, Trager S, Nassif E, Saint A, Hammel P, Lecaille C, Bureau M, Perrier M, Botsen D, Bourgeois V, Taieb J, Auclin E

Int J Cancer. 2022 06 15;:

Impact of the COVID-19 pandemic on disease stage and treatment for patients with pancreatic adenocarcinoma: A French comprehensive multicentre ambispective observational cohort study (CAPANCOVID).

Brugel M, Letrillart L, Evrard C, Thierry A, Tougeron D, El Amrani M, Piessen G, Truant S, Turpin A, d'Engremont C, Roth G, Hautefeuille V, Regimbeau JM, Williet N, Schwarz L, Di Fiore F, Borg C, Doussot A, Lambert A, Moulin V, Trelohan H, Bolliet M, Topolscki A, Ayav A, Lopez A, Botsen D, Piardi T, Carlier C, Bouché O

Eur J Cancer. 2022 Feb 10;166:8-20

Iliac periostitis revealing acute leukemia.

Lambert A, Ramon A, Jacob D, Ornetti P

Joint Bone Spine. 2022 Feb 3;:105351

COVID-19 Infections in Cancer Patients Were Frequently Asymptomatic: Description From a French Prospective Multicenter Cohort (PAPESCO-19).

Zhou K, Raoul JL, Blanc-Lapierre A, Seegers V, Boisdron-Celle M, Bourdon M, Mahammedi H, Lambert A, Moreau-Bachelard C, Campone M, Conroy T, Penault-Llorca F, Bellanger MM, Bigot F

Clin Med Insights Oncol. 2022 ;16:11795549221090187

Neoadjuvant Treatment Strategies in Resectable Pancreatic Cancer.

Lambert A, Schwarz L, Ducreux M, Conroy T

Cancers (Basel). 2021 Sep 21;13(18):

Anosmia but Not Ageusia as a COVID-19-Related Symptom among Cancer Patients-First Results from the PAPESCO-19 Cohort Study.

Zhou K, Blanc-Lapierre A, Seegers V, Boisdron-Celle M, Bigot F, Bourdon M, Mahammedi H, Lambert A, Campone M, Conroy T, Penault-Llorca F, Bellanger MM, Raoul JL

Cancers (Basel). 2021 Jul 6;13(14):

Future directions in drug development in pancreatic cancer.

Lambert A, Conroy T, Ducreux M

Semin Oncol. 2021 Feb 23;:

Intrapericardial instillation of bleomycin prevents recurrence of malignant pericardial effusions: Series of 46 cases and comprehensive literature review.

Lambert A, Salleron J, Kieffer A, Raymond P, Geoffrois L, Gavoille C

Bull Cancer. 2020 Jun 5;:

Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer.

Franczak C, Witz A, Geoffroy K, Demange J, Rouyer M, Husson M, Massard V, Gavoille C, Lambert A, Gilson P, Gambier N, Scala-Bertola J, Merlin JL, Harlé A

PLoS ONE. 2020 ;15(1):e0227294

An update on treatment options for pancreatic adenocarcinoma.

Lambert A, Schwarz L, Borbath I, Henry A, Van Laethem JL, Malka D, Ducreux M, Conroy T

Ther Adv Med Oncol. 2019 ;11:1758835919875568

Comparison of Three Real-Time PCR Assays for the Detection of PIK3CA Somatic Mutations in Formalin-Fixed Paraffin Embedded Tissues of Patients with Breast Carcinomas.

Lambert A, Salleron J, Lion M, Rouyer M, Lozano N, Leroux A, Merlin JL, Harlé A

Pathol. Oncol. Res.. 2018 Nov 13;:

Current status on the place of FOLFIRINOX in metastatic pancreatic cancer and future directions.

Lambert A, Gavoille C, Conroy T

Therap Adv Gastroenterol. 2017 Aug;10(8):631-645

Response to FOLFIRINOX by gender in patients with metastatic pancreatic cancer: Results from the PRODIGE 4/ ACCORD 11 randomized trial.

Lambert A, Jarlier M, Gourgou Bourgade S, Conroy T

PLoS ONE. 2017 ;12(9):e0183288

Current standards and new innovative approaches for treatment of pancreatic cancer.

Conroy T, Bachet JB, Ayav A, Huguet F, Lambert A, Caramella C, Maréchal R, Van Laethem JL, Ducreux M

Eur. J. Cancer. 2016 Apr;57:10-22

Impact of systematic ultrasound of the knee on the rheumatologist's clinical decision in patients consulting for knee pain.

Couturier M, Arbault A, Laroche D, Contant E, Lambert A, Pottecher P, Ornetti P

Rheumatol Int. 2016 Feb;36(2):283-8

[Drug-induced pancreatitis. A review of French spontaneous reports].

Chebane L, Bagheri H, Hillaire-Buys D, Géniaux H, Yahioui N, Laroche ML, Cottin J, Spreux A, Mosquet B, Pecriaux C, Bellet F, Lambert A, Montastruc JL

Rev Med Interne. 2015 Sep;36(9):573-8

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