Abrey-Recalde MJ, Mialhe F, Le TK, Radoua A, Lagorgette L, Belkaid R, Mamode Cassim A, Gonzalez D, Jacquin E, Gobbo J, Bibeau F, Lepage C, Xu L, He X, Derangère V, Lirussi F, Jego G, Ye XY, Hermetet F, Garrido C

Cell Death Dis. 2026 05 19;:

First-in-class inhibitor of HSP110 blocks BCR activation through SYK phosphorylation in diffuse large B-cell lymphoma.

Gibouin VC, Durand M, Boudesco C, Hermetet F, Nozickova K, Chassagne-Clement C, Abdelwahed M, Klener P, Garrido C, Jego G

Leukemia. 2024 06 21;:

A first-in-class inhibitor of HSP110 to potentiate XPO1-targeted therapy in primary mediastinal B-cell lymphoma and classical Hodgkin lymphoma.

Durand M, Cabaud Gibouin V, Duplomb L, Salmi L, Caillot M, Sola B, Camus V, Jardin F, Garrido C, Jego G

J Exp Clin Cancer Res. 2024 05 22;43(1):148

Heat-Shock Proteins in Leukemia and Lymphoma: Multitargets for Innovative Therapeutic Approaches.

Cabaud-Gibouin V, Durand M, Quéré R, Girodon F, Garrido C, Jego G

Cancers (Basel). 2023 02 3;15(3):

Mutation Modifies Exportin 1 Localisation and Interactome in B-cell Lymphoma.

Miloudi H, Bohers É, Guillonneau F, Taly A, Gibouin VC, Viailly PJ, Jego G, Grumolato L, Jardin F, Sola B

. 2020 Sep 30;12(10):

Heat Shock Proteins and PD-1/PD-L1 as Potential Therapeutic Targets in Myeloproliferative Neoplasms.

De Almeida S, Regimbeau M, Jego G, Garrido C, Girodon F, Hermetet F

Cancers (Basel). 2020 Sep 11;12(9):

Neutralization of HSF1 in cells from PIK3CA-related overgrowth spectrum patients blocks abnormal proliferation.

Da Costa R, De Almeida S, Chevarin M, Hadj-Rabia S, Leclerc-Mercier S, Thauvin-Robinet C, Garrido C, Faivre L, Vabres P, Duplomb L, Jego G

Biochem. Biophys. Res. Commun.. 2020 Jun 30;:

Chaperoning STAT3/5 by Heat Shock Proteins: Interest of Their Targeting in Cancer Therapy.

Jego G, Hermetet F, Girodon F, Garrido C

Cancers (Basel). 2019 Dec 19;12(1):

Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.

Gozzi GJ, Gonzalez D, Boudesco C, Dias AMM, Gotthard G, Uyanik B, Dondaine L, Marcion G, Hermetet F, Denis C, Hardy L, Suzanne P, Douhard R, Jego G, Dubrez L, Demidov ON, Neiers F, Briand L, Sopková-de Oliveira Santos J, Voisin-Chiret AS, Garrido C

Cell Death Differ.. 2019 May 8;:

Serpin B1 defect and increased apoptosis of neutrophils in Cohen syndrome neutropenia.

Duplomb L, Rivière J, Jego G, Da Costa R, Hammann A, Racine J, Schmitt A, Droin N, Capron C, Gougerot-Pocidalo MA, Dubrez L, Aral B, Lafon A, Edery P, Ghoumid J, Blair E, El Chehadeh-Djebbar S, Carmignac V, Thevenon J, Guy J, Girodon F, Bastie JN, Delva L, Faivre L, Thauvin-Robinet C, Solary E

J. Mol. Med.. 2019 Mar 7;:

HSP110 sustains chronic NF-κB signaling in activated B cell diffuse large B cell lymphoma through MyD88 stabilization.

Boudesco C, Verhoeyen E, Martin L, Chassagne-Clement C, Salmi L, Mhaidly R, Pangault C, Fest T, Ramla S, Jardin F, Wolz OO, Weber ANR, Garrido C, Jego G

Blood. 2018 Jun 5;:

Hsp70: A Cancer Target Inside and Outside the Cell.

Boudesco C, Cause S, Jego G, Garrido C

Methods Mol. Biol.. 2018 ;1709:371-396

Modulation of the inwardly rectifying potassium channel Kir4.1 by the pro-invasive miR-5096 in glioblastoma cells.

Thuringer D, Chanteloup G, Boucher J, Pernet N, Boudesco C, Jego G, Chatelier A, Bois P, Gobbo J, Cronier L, Solary E, Garrido C

Oncotarget. 2017 Apr;:

Serum Gp96 is a chaperone of complement-C3 during graft-versus-host disease.

Seignez A, Joly AL, Chaumonnot K, Hazoumé A, Sanka M, Marcion G, Boudesco C, Hammann A, Seigneuric R, Jégo G, Ducoroy P, Delarue P, Senet P, Castilla-Llorente C, Solary E, Durey MA, Rubio MT, Hermine O, Kohli E, Garrido C

JCI Insight. 2017 Mar;2(6):e90531

Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions.

Thuringer D, Boucher J, Jego G, Pernet N, Cronier L, Hammann A, Solary E, Garrido C

Oncotarget. 2016 Nov 8;7(45):73925-73934

HSP110 promotes colorectal cancer growth through STAT3 activation.

Berthenet K, Bokhari A, Lagrange A, Marcion G, Boudesco C, Causse S, De Thonel A, Svrcek M, Goloudina AR, Dumont S, Hammann A, Biard DS, Demidov ON, Seigneuric R, Duval A, Collura A, Jego G, Garrido C

Oncogene. 2016 Nov;:

Extracellular HSP110 skews macrophage polarization in colorectal cancer.

Berthenet K, Boudesco C, Collura A, Svrcek M, Richaud S, Hammann A, Causse S, Yousfi N, Wanherdrick K, Duplomb L, Duval A, Garrido C, Jego G

Oncoimmunology. 2016 Jul;5(7):e1170264

The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and inhibits graft versus host disease development.

Joly AL, Deepti A, Seignez A, Goloudina A, Hebrard S, Schmitt E, Richaud S, Fourmaux E, Hammann A, Collura A, Svrcek M, Jego G, Robinet E, Solary E, Demidov O, Kohli E, Garrido C

Oncogene. 2016 Jun;35(22):2948

Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis.

Thuringer D, Jego G, Berthenet K, Hammann A, Solary E, Garrido C

Oncotarget. 2016 May;7(19):28160-8

Biofilms of Lactobacillus plantarum and Lactobacillus fermentum: Effect on stress responses, antagonistic effects on pathogen growth and immunomodulatory properties.

Aoudia N, Rieu A, Briandet R, Deschamps J, Chluba J, Jego G, Garrido C, Guzzo J

Food Microbiol.. 2016 Feb;53(Pt A):51-9

Insulin response dysregulation explains abnormal fat storage and increased risk of diabetes mellitus type 2 in Cohen Syndrome.

Limoge F, Faivre L, Gautier T, Petit JM, Gautier E, Masson D, Jego G, El Chehadeh-Djebbar S, Marle N, Carmignac V, Deckert V, Brindisi MC, Edery P, Ghoumid J, Blair E, Lagrost L, Thauvin-Robinet C, Duplomb L

Hum Mol Genet. 2015 Sep 10. pii: ddv366.

The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and inhibits graft versus host disease development.

Joly AL, Deepti A, Seignez A, Goloudina A, Hebrard S, Schmitt E, Richaud S, Fourmaux E, Hammann A, Collura A, Svrcek M, Jego G, Robinet E, Solary E, Demidov O, Kohli E, Garrido C

Oncogene. 2015 Sep 14

Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells.

Thuringer D, Berthenet K, Cronier L, Jego G, Solary E, Garrido C

Oncotarget. 2015 Mar 10.

Do not stress, just differentiate: role of stress proteins in hematopoiesis.

Boudesco C, Rattier T, Garrido C, Jego G

Cell Death Dis. 2015 Jan 29;6:e1628

The biofilm mode of life boosts the anti-inflammatory properties of Lactobacillus.

Rieu A, Aoudia N, Jego G, Chluba J, Yousfi N, Briandet R, Deschamps J, Gasquet B, Monedero V, Garrido C, Guzzo J

Cell Microbiol. 2014 Dec;16(12):1836-53

Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes.

Jego G, Lanneau D, De Thonel A, Berthenet K, Hazoumé A, Droin N, Hamman A, Girodon F, Bellaye PS, Wettstein G, Jacquel A, Duplomb L, Le Mouël A, Papanayotou C, Christians E, Bonniaud P, Lallemand-Mezger V, Solary E, Garrido C

Leukemia. 2014 Aug;28(8):1676-86

Cohen syndrome is associated with major glycosylation defects.

Duplomb L, Duvet S, Picot D, Jego G, El Chehadeh-Djebbar S, Marle N, Gigot N, Aral B, Carmignac V, Thevenon J, Lopez E, Riviere JB, Klein A, Philippe C, Droin N, Blair E, Girodon F, Donadieu J, Bellanne-Chantelot C, Delva L, Michalski JC, Solary E, Faivre L, Foulquier F, Thauvin-Robinet C

Hum Mol Genet. 2014 May 1;23(9):2391-9

Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells.

de Thonel A, Hazoume A, Kochin V, Isoniemi K, Jego G, Fourmaux E, Hammann A, Mjahed H, Filhol O, Micheau O, Rocchi P, Mezger V, Eriksson JE, Rangnekar VM, Garrido C

Cell Death Dis. 2014 Jan 23;5:e1016

Extracellular HSP27 mediates angiogenesis through Toll-like receptor 3.

Thuringer D, Jego G, Wettstein G, Terrier O, Cronier L, Yousfi N, Hebrard S, Bouchot A, Hazoume A, Joly AL, Gleave M, Rosa-Calatrava M, Solary E, Garrido C

FASEB J. 2013 Oct;27(10):4169-83

Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis.

Dorard C, de Thonel A, Collura A, Marisa L, Svrcek M, Lagrange A, Jego G, Wanherdrick K, Joly AL, Buhard O, Gobbo J, Penard-Lacronique V, Zouali H, Tubacher E, Kirzin S, Selves J, Milano G, Etienne-Grimaldi MC, Bengrine-Lefevre L, Louvet C, Tournigand C, Lefevre JH, Parc Y, Tiret E, Flejou JF, Gaub MP, Garrido C, Duval A

Nat Med. 2011 Sep 25;17(10):1283-9