Dr BEN SHEM Adam

Fiche personne

Coordonnées

IGBMC
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH Cedex

03 69 48 52 99

Territoire

Alsace

Statut

Chercheur

Affiliation

IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)

Équipes/plateformes

Equipe "Biologie structurale intégrative / Architecture des systèmes nucléoprotéiques par microscopie électronique 3D"

Projets

Etude de l'organisation structurale de SWI/SNF, un assemblage protéique impliqué dans le remodelage de la chromatine

2016 - Porteur du projet : Dr BEN SHEM Adam

Publications

Step-brothers in arms, SAGA and ATAC co-activator complexes, use different strategies.

Rizzo F, Ben-Shem A, Timmers HTM, Bartke T, Vincent SD, Tora L

EMBO J. 2026 08 11;:

Insights into the structure and evolution of the human SAGA complex by affinity-ligand purification.

Damilot M, Schoeps T, Tora L, Schultz P, Lebeau L, Papai G, Ben-Shem A

Sci Adv. 2026 03 20;12(12):eaec8104

Specific Binding Modes of the SIRT6 C-Terminal Domain to the Nucleosome Core Particle Influence DNA Unwrapping and H3K27 Accessibility.

Qiu Y, Papai G, Ben Shem A, Bignon E

J Phys Chem B. 2025 09 24;:

Structure of human TIP60-C histone exchange and acetyltransferase complex.

Li C, Smirnova E, Schnitzler C, Crucifix C, Concordet JP, Brion A, Poterszman A, Schultz P, Papai G, Ben-Shem A

Nature. 2024 09 11;:

Binding to nucleosome poises human SIRT6 for histone H3 deacetylation.

Smirnova E, Bignon E, Schultz P, Papai G, Ben Shem A

Elife. 2024 02 28;12:

The structure of the NuA4-Tip60 complex reveals the mechanism and importance of long-range chromatin modification.

Fréchard A, Faux C, Hexnerova R, Crucifix C, Papai G, Smirnova E, McKeon C, Ping FLY, Helmlinger D, Schultz P, Ben-Shem A

Nat Struct Mol Biol. 2023 08 7;:

Atomic structure of the SAGA complex and it's interaction with TBP.

Papai G, Frechard A, Kolesnikova O, Crucifix C, Schultz P, Ben-Shem A

C R Biol. 2021 Feb 4;343(3):247-255

Architecture of the multi-functional SAGA complex and the molecular mechanism of holding TBP.

Ben-Shem A, Papai G, Schultz P

FEBS J.. 2020 Sep 18;:

Structure of SAGA and mechanism of TBP deposition on gene promoters.

Papai G, Frechard A, Kolesnikova O, Crucifix C, Schultz P, Ben-Shem A

Nature. 2020 Jan 22;:

Molecular structure of promoter-bound yeast TFIID.

Kolesnikova O, Ben-Shem A, Luo J, Ranish J, Schultz P, Papai G

Nat Commun. 2018 Nov 7;9(1):4666

Insights into the origin of the nuclear localization signals in conserved ribosomal proteins.

Melnikov S, Ben-Shem A, Yusupova G, Yusupov M

Nat Commun. 2015 Jun 11;6:7382

Fiche personne Projets Publications

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