Fiche personne
Coordonnées
Institut de biologie moléculaire et cellulaire
2 allée Konrad Roentgen
67084 STRASBOURG Cedex
03 88 41 70 03
Territoire
Alsace
Statut
Ingénieur/Technicien
Équipes/plateformes
Publications
Dengue virus harnesses mosquito Syntenin to load and secrete viral RNA into salivary exosomes.
Rachenne F, Schneider N, Rey-Cadilhac F, Serrato-Pomar I, Pruvost L, Di Pietro L, Dainat J, Vernet A, Cazevieille C, Ancelin A, Lai Kee Him J, Jansen S, Miot EF, Fraering J, Simon L, Missé D, Morille M, Hammann P, Seveno M, Urbach S, Dallmeier K, Marois É, Pompon J
Proc Natl Acad Sci U S A. 2026 03 24;123(12):e2520697123
Tuning of the RBR1-E2F/DP transcriptional module by the F-box protein FBL17.
Espanet J, He X, Pan T, Gentric N, Potuschak T, Desvoyes B, Hammann P, Chicher J, Brik R, Lechner E, Latrasse D, Pettkó-Szandtner A, Gutierrez C, Raynaud C, Magyar Z, Benhamed M, Yan S, Noir S, Genschik P
Sci Adv. 2026 02 20;12(8):eadz2439
α2-macroglobulin function of thioester-containing proteins guards from a bacterial protease via two immune-induced peptides.
Cai C, Acker A, Huang J, Liu Y, Molino MV, Mariscotti JF, Garcia-Véscovi E, Bulet P, Hammann P, Chicher J, Liegeois S, Li Z, Hoffmann JA, Matt N, Ferrandon D
Proc Natl Acad Sci U S A. 2026 01 27;123(4):e2525580123
GPRASP1 deletion suppresses antinociceptive tolerance during chronic activation of delta opioid receptor in persistent pain.
Kaeffer J, Straub ML, Le Coz GM, Quillet R, Kugler V, Petit-Demoulière N, Gerum M, Zeder-Lutz G, Doridot S, Dumas M, Chicher J, Hammann P, Marin P, Vandermoere F, Massotte D, Simonin F, Lecat S
Biomed Pharmacother. 2026 01 6;194:118913
Galectin-3 Mediated Endocytosis of the Orphan G-Protein-Coupled Receptor GPRC5A.
Boucheham A, Franco JM, Bär S, MacDonald E, Zuttion S, Blagec L, Rinaldi B, Chicher J, Kuhn L, Hammann P, Wunder C, Johannes L, Rechreche H, Friant S
Cells. 2025 10 9;14(19):
Neutrophils display antibacterial defense via non-canonical LC3 decoration of extracellular bacteria.
Skerniskyte J, Barroso MV, Chicher J, Hammann P, Demais V, Wright K, Mostowy S, Marteyn BS
Microbes Infect. 2025 07 3;:105545
In vivo Dicer-2 interactome during viral infection reveals novel pro and antiviral factors in Drosophila melanogaster.
Rousseau C, Morand T, Haas G, Lauret E, Kuhn L, Chicher J, Hammann P, Meignin C
PLoS Pathog. 2025 05;21(5):e1013093
Cross-Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium.
Hirschler E, Glattard E, Arnaud N, Chicher J, Hammann P, Leize-Wagner E, Bechinger B, Potier N
Rapid Commun Mass Spectrom. 2025 04 27;:e10044
Neutrophils Display Novel Partners of Cytosolic Proliferating Cell Nuclear Antigen Involved in Interferon Response in COVID-19 Patients.
Pesenti L, de Oliveira Formiga R, Tamassia N, Gardiman E, Chable de La Héronnière F, Gasperini S, Chicher J, Kuhn L, Hammann P, Le Gall M, Saraceni-Tasso G, Martin C, Hosmalin A, Breckler M, Hervé R, Decker P, Ladjemi MZ, Pène F, Burgel PR, Cassatella MA, Witko-Sarsat V
J Innate Immun. 2025 02 27;17(1):154-175
NDUFAF3 is Involved in the Assembly of the Q/P Modules of Respiratory Complex I in the Green Microalga Chlamydomonas reinhardtii.
Salinas-Giegé T, Ticoras M, Waltz F, Coosemans N, Fanara S, Chicher J, Hammann P, Hamel PP, Remacle C
Physiol Plant. 2025 ;177(4):e70406
CLSY docking to Pol IV requires a conserved domain critical for small RNA biogenesis and transposon silencing.
Felgines L, Rymen B, Martins LM, Xu G, Matteoli C, Himber C, Zhou M, Eis J, Coruh C, Böhrer M, Kuhn L, Chicher J, Pandey V, Hammann P, Wohlschlegel J, Waltz F, Law JA, Blevins T
Nat Commun. 2024 11 27;15(1):10298
DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection.
Messmer M, Pierson L, Pasquier C, Djordjevic N, Chicher J, Hammann P, Pfeffer S, Girardi E
Virol J. 2024 03 29;21(1):76
Heat stress promotes Arabidopsis AGO1 phase separation and association with stress granule components.
Blagojevic A, Baldrich P, Schiaffini M, Lechner E, Baumberger N, Hammann P, Elmayan T, Garcia D, Vaucheret H, Meyers BC, Genschik P
iScience. 2024 03 15;27(3):109151
Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp.
Compain G, Monsarrat C, Blagojevic J, Brillet K, Dumas P, Hammann P, Kuhn L, Martiel I, Engilberge S, Oliéric V, Wolff P, Burnouf DY, Wagner J, Guichard G
JACS Au. 2024 02 26;4(2):432-440
A tRNA-modifying enzyme facilitates RNase P activity in Arabidopsis nuclei.
Arrivé M, Bruggeman M, Skaltsogiannis V, Coudray L, Quan YF, Schelcher C, Cognat V, Hammann P, Chicher J, Wolff P, Gobert A, Giegé P
Nat Plants. 2023 11 9;:
Cell-type-specific control of secondary cell wall formation by Musashi-type translational regulators in .
Kairouani A, Pontier D, Picart C, Mounet F, Martinez Y, Le-Bot L, Fanuel M, Hammann P, Belmudes L, Merret R, Azevedo J, Carpentier MC, Gagliardi D, Couté Y, Sibout R, Bies-Etheve N, Lagrange T
Elife. 2023 09 29;12:
Systematic identification of factors involved in the silencing of germline genes in mouse embryonic stem cells.
Al Adhami H, Vallet J, Schaal C, Schumacher P, Bardet AF, Dumas M, Chicher J, Hammann P, Daujat S, Weber M
Nucleic Acids Res. 2023 02 11;:
Exploring Protein Interactome Data with IPinquiry: Statistical Analysis and Data Visualization by Spectral Counts.
Kuhn L, Vincent T, Hammann P, Zuber H
Methods Mol Biol. 2023 ;2426:243-265
Proteomics-based determination of double stranded RNA interactome reveals known and new factors involved in Sindbis virus infection.
Girardi E, Messmer M, Lopez P, Fender A, Chicher J, Chane-Woon-Ming B, Hammann P, Pfeffer S
RNA. 2022 12 20;:
A Methylotrophic Bacterium Growing with the Antidiabetic Drug Metformin as Its Sole Carbon, Nitrogen and Energy Source.
Chaignaud P, Gruffaz C, Borreca A, Fouteau S, Kuhn L, Masbou J, Rouy Z, Hammann P, Imfeld G, Roche D, Vuilleumier S
Microorganisms. 2022 11 21;10(11):
FRIENDLY (FMT) is an RNA binding protein associated with cytosolic ribosomes at the mitochondrial surface.
Hemono M, Salinas-Giegé T, Roignant J, Vingadassalon A, Hammann P, Ubrig E, Ngondo P, Duchêne AM
Plant J. 2022 09 1;:
The Arabidopsis F-box protein FBW2 targets AGO1 for degradation to prevent spurious loading of illegitimate small RNA.
Hacquard T, Clavel M, Baldrich P, Lechner E, Pérez-Salamó I, Schepetilnikov M, Derrien B, Dubois M, Hammann P, Kuhn L, Brun D, Bouteiller N, Baumberger N, Vaucheret H, Meyers BC, Genschik P
Cell Rep. 2022 Apr 12;39(2):110671
How the Presence of Hemin Affects the Expression of the Different Iron Uptake Pathways in Cells.
Normant V, Kuhn L, Munier M, Hammann P, Mislin GLA, Schalk IJ
ACS Infect Dis. 2021 Dec 8;:
A NYN domain protein directly interacts with DECAPPING1 and is required for phyllotactic pattern.
Schiaffini M, Chicois C, Pouclet A, Chartier T, Ubrig E, Gobert A, Zuber H, Mutterer J, Chicher J, Kuhn L, Hammann P, Gagliardi D, Garcia D
Plant Physiol. 2021 Nov 13;:
A role for PchHI as the ABC transporter in iron acquisition by the siderophore pyochelin in Pseudomonas aeruginosa.
Roche B, Garcia-Rivera MA, Normant V, Kuhn L, Hammann P, Brönstrup M, Mislin GLA, Schalk IJ
Environ Microbiol. 2021 Oct 18;:
Brain adiponectin signaling controls peripheral insulin response in Drosophila.
Arquier N, Bjordal M, Hammann P, Kuhn L, Léopold P
Nat Commun. 2021 Sep 24;12(1):5633
Chemical Modifications Induced by Phthalic Anhydride, a Respiratory Sensitizer, in Reconstructed Human Epidermis: A Combined HRMAS NMR and LC-MS/MS Proteomic Approach.
Khong MT, Berl V, Kuhn L, Hammann P, Lepoittevin JP
Chem Res Toxicol. 2021 Aug 9;:
Phosphorylation of a reinitiation supporting protein, RISP, determines its function in translation reinitiation.
Mancera-Martínez E, Dong Y, Makarian J, Srour O, Thiébeauld O, Jamsheer M, Chicher J, Hammann P, Schepetilnikov M, Ryabova LA
Nucleic Acids Res. 2021 Jun 16;:
E2F6 initiates stable epigenetic silencing of germline genes during embryonic development.
Dahlet T, Truss M, Frede U, Al Adhami H, Bardet AF, Dumas M, Vallet J, Chicher J, Hammann P, Kottnik S, Hansen P, Luz U, Alvarez G, Auclair G, Hecht J, Robinson PN, Hagemeier C, Weber M
Nat Commun. 2021 Jun 11;12(1):3582
Human DICER helicase domain recruits PKR and modulates its antiviral activity.
Montavon TC, Baldaccini M, Lefèvre M, Girardi E, Chane-Woon-Ming B, Messmer M, Hammann P, Chicher J, Pfeffer S
PLoS Pathog. 2021 May;17(5):e1009549
Cex1 is a component of the COPI intracellular trafficking machinery.
Enkler L, Rinaldi B, de Craene JO, Hammann P, Nureki O, Senger B, Friant S, Becker HD
Biol Open. 2021 Mar 22;10(3):
The Esterase PfeE, the Achilles' Heel in the Battle for Iron between and .
Gasser V, Kuhn L, Hubert T, Aussel L, Hammann P, Schalk IJ
Int J Mol Sci. 2021 Mar 10;22(6):
The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis.
Scheer H, de Almeida C, Ferrier E, Simonnot Q, Poirier L, Pflieger D, Sement FM, Koechler S, Piermaria C, Krawczyk P, Mroczek S, Chicher J, Kuhn L, Dziembowski A, Hammann P, Zuber H, Gagliardi D
Nat Commun. 2021 Feb 26;12(1):1298
Opportunistic use of catecholamine neurotransmitters as siderophores to access iron by Pseudomonas aeruginosa.
Perraud Q, Kuhn L, Fritsch S, Graulier G, Gasser V, Normant V, Hammann P, Schalk IJ
Environ Microbiol. 2020 Dec 21;:
The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation.
Tidu A, Janvier A, Schaeffer L, Sosnowski P, Kuhn L, Hammann P, Westhof E, Eriani G, Martin F
RNA. 2020 Dec 2;:
Nocardamine-dependent iron uptake in Pseudomonas aeruginosa: exclusive involvement of the FoxA outer membrane transporter.
Normant V, Josts I, Kuhn L, Perraud Q, Fritsch S, Hammann P, Mislin GLA, Tidow H, Schalk IJ
ACS Chem. Biol.. 2020 Sep 9;:
Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress.
Kröll-Hermi A, Ebstein F, Stoetzel C, Geoffroy V, Schaefer E, Scheidecker S, Bär S, Takamiya M, Kawakami K, Zieba BA, Studer F, Pelletier V, Eyermann C, Speeg-Schatz C, Laugel V, Lipsker D, Sandron F, McGinn S, Boland A, Deleuze JF, Kuhn L, Chicher J, Hammann P, Friant S, Etard C, Krüger E, Muller J, Strähle U, Dollfus H
EMBO Mol Med. 2020 Jun 5;:e11861
Phenotypic Adaption of Pseudomonas aeruginosa by Hacking Siderophores Produced by Other Microorganisms.
Perraud Q, Cantero P, Roche B, Gasser V, Normant VP, Kuhn L, Hammann P, Mislin GLA, Ehret-Sabatier L, Schalk IJ
Mol Cell Proteomics. 2020 Apr;19(4):589-607
YBEY is an essential biogenesis factor for mitochondrial ribosomes.
Summer S, Smirnova A, Gabriele A, Toth U, Fasemore AM, Förstner KU, Kuhn L, Chicher J, Hammann P, Mitulović G, Entelis N, Tarassov I, Rossmanith W, Smirnov A
Nucleic Acids Res.. 2020 Mar 17;:
CUL3 E3 ubiquitin ligases regulate MYC2, MYC3, and MYC4 stability and JA responses.
Chico JM, Lechner E, Fernandez-Barbero G, Canibano E, García-Casado G, Franco-Zorrilla JM, Hammann P, Zamarreño AM, García-Mina JM, Rubio V, Genschik P, Solano R
Proc. Natl. Acad. Sci. U.S.A.. 2020 Mar 2;:
Phenotypic adaption of by hacking siderophores produced by other microorganisms.
Perraud Q, Cantero P, Roche B, Gasser V, Normant VP, Kuhn L, Hammann P, Mislin GLA, Ehret-Sabatier L, Schalk IJ
Mol. Cell Proteomics. 2020 Feb 5;:
Proteomic Analysis of DNA Synthesis on a Structured DNA Template in Human Cellular Extracts: Interplay Between NHEJ and Replication-Associated Proteins.
Janel-Bintz R, Kuhn L, Frit P, Chicher J, Wagner J, Haracska L, Hammann P, Cordonnier AM
Proteomics. 2020 Jan 30;:e1900184
RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis.
Lange H, Ndecky SYA, Gomez-Diaz C, Pflieger D, Butel N, Zumsteg J, Kuhn L, Piermaria C, Chicher J, Christie M, Karaaslan ES, Lang PLM, Weigel D, Vaucheret H, Hammann P, Gagliardi D
Nat Commun. 2019 Aug 27;10(1):3871
Determination of protein-only RNase P interactome in Arabidopsis mitochondria and chloroplasts identifies a complex between PRORP1 and another NYN domain nuclease.
Bouchoucha A, Waltz F, Bonnard G, Arrivé M, Hammann P, Kuhn L, Schelcher C, Zuber H, Gobert A, Giegé P
Plant J.. 2019 Jul 18;:
tRNA Maturation Defects Lead to Inhibition of rRNA Processing via Synthesis of pppGpp.
Trinquier A, Ulmer JE, Gilet L, Figaro S, Hammann P, Kuhn L, Braun F, Condon C
Mol. Cell. 2019 Apr 5;:
Small is big in Arabidopsis mitochondrial ribosome.
Waltz F, Nguyen TT, Arrivé M, Bochler A, Chicher J, Hammann P, Kuhn L, Quadrado M, Mireau H, Hashem Y, Giegé P
Nat Plants. 2019 Jan;5(1):106-117
Blocking nuclear export of HSPA8 after heat shock stress severely alters cell survival.
Wang F, Bonam SR, Schall N, Kuhn L, Hammann P, Chaloin O, Madinier JB, Briand JP, Page N, Muller S
Sci Rep. 2018 Nov 14;8(1):16820
Control of dengue virus in the midgut of Aedes aegypti by ectopic expression of the dsRNA-binding protein Loqs2.
Olmo RP, Ferreira AGA, Izidoro-Toledo TC, Aguiar ERGR, de Faria IJS, de Souza KPR, Osório KP, Kuhn L, Hammann P, de Andrade EG, Todjro YM, Rocha MN, Leite THJF, Amadou SCG, Armache JN, Paro S, de Oliveira CD, Carvalho FD, Moreira LA, Marois E, Imler JL, Marques JT
Nat Microbiol. 2018 Oct 29;:
ATG5 is required for B cell polarization and presentation of particulate antigens.
Arbogast F, Arnold J, Hammann P, Kuhn L, Chicher J, Murera D, Weishaar J, Muller S, Fauny JD, Gros F
Autophagy. 2018 Sep 8;:
The UPF1 interactome reveals interaction networks between RNA degradation and translation repression factors in Arabidopsis.
Chicois C, Scheer H, Garcia S, Zuber H, Mutterer J, Chicher J, Hammann P, Gagliardi D, Garcia D
Plant J.. 2018 Jul 7;:
Toxicological effects of CdSe nanocrystals on the marine diatom Phaeodactylum tricornutum: The first mass spectrometry-based proteomic approach.
Poirier I, Pallud M, Kuhn L, Hammann P, Demortière A, Jamali A, Chicher J, Caplat C, Gallon RK, Bertrand M
Ecotoxicol. Environ. Saf.. 2018 May 15;152:78-90
Characterization of DCL4 missense alleles provides insights into its ability to process distinct classes of dsRNA substrates.
Montavon T, Kwon Y, Zimmermann A, Hammann P, Vincent T, Cognat V, Bergdoll M, Michel F, Dunoyer P
Plant J.. 2018 Apr 22;:
Definition of a RACK1 Interaction Network in Using SWATH-MS.
Kuhn L, Majzoub K, Einhorn E, Chicher J, Pompon J, Imler JL, Hammann P, Meignin C
G3 (Bethesda). 2017 Jul 5;7(7):2249-2258
Neutralization of mobile antiviral small RNA through peroxisomal import.
Incarbone M, Zimmermann A, Hammann P, Erhardt M, Michel F, Dunoyer P
Nat Plants. 2017 Jun 19;3:17094
GTPase ROP2 binds and promotes activation of target of rapamycin, TOR, in response to auxin.
Schepetilnikov M, Makarian J, Srour O, Geldreich A, Yang Z, Chicher J, Hammann P, Ryabova LA
EMBO J.. 2017 04 3;36(7):886-903
A specific dsRNA-binding protein complex selectively sequesters endogenous inverted-repeat siRNA precursors and inhibits their processing.
Montavon T, Kwon Y, Zimmermann A, Hammann P, Vincent T, Cognat V, Michel F, Dunoyer P
Nucleic Acids Res.. 2017 02 17;45(3):1330-1344
Nonconventional localizations of cytosolic aminoacyl-tRNA synthetases in yeast and human cells.
Debard S, Bader G, De Craene JO, Enkler L, Bär S, Laporte D, Hammann P, Myslinski E, Senger B, Friant S, Becker HD
Methods. 2017 Jan;113:91-104
A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi.
Stoetzel C, Bär S, De Craene JO, Scheidecker S, Etard C, Chicher J, Reck JR, Perrault I, Geoffroy V, Chennen K, Strähle U, Hammann P, Friant S, Dollfus H
Nat Commun. 2016 Nov;7:13586
Ability of the marine bacterium Pseudomonas fluorescens BA3SM1 to counteract the toxicity of CdSe nanoparticles.
Poirier I, Kuhn L, Demortière A, Mirvaux B, Hammann P, Chicher J, Caplat C, Pallud M, Bertrand M
J Proteomics. 2016 10 4;148:213-27
Modulation of plant growth in vivo and identification of kinase substrates using an analog-sensitive variant of CYCLIN-DEPENDENT KINASE A;1.
Harashima H, Dissmeyer N, Hammann P, Nomura Y, Kramer K, Nakagami H, Schnittger A
BMC Plant Biol.. 2016 Sep 26;16(1):209
Identification of factors involved in target RNA-directed microRNA degradation.
Haas G, Cetin S, Messmer M, Chane-Woon-Ming B, Terenzi O, Chicher J, Kuhn L, Hammann P, Pfeffer S
Nucleic Acids Res.. 2016 Apr;44(6):2873-87
Improvement of Mitochondria Extract from Saccharomyces cerevisiae Characterization in Shotgun Proteomics Using Sheathless Capillary Electrophoresis Coupled to Tandem Mass Spectrometry.
Ibrahim M, Gahoual R, Enkler L, Becker HD, Chicher J, Hammann P, François YN, Kuhn L, Leize-Wagner E
J Chromatogr Sci. 2016 Apr;54(4):653-63
Proteome analysis of digestive fluids in Nepenthes pitchers.
Rottloff S, Miguel S, Biteau F, Nisse E, Hammann P, Kuhn L, Chicher J, Bazile V, Gaume L, Mignard B, Hehn A, Bourgaud F
Ann. Bot.. 2016 Mar;117(3):479-95
Nucleic acid import into mitochondria: New insights into the translocation pathways.
Weber-Lotfi F, Koulintchenko MV, Ibrahim N, Hammann P, Mileshina DV, Konstantinov YM, Dietrich A
Biochim. Biophys. Acta. 2015 Dec;1853(12):3165-81
Purification of mRNA-programmed translation initiation complexes suitable for mass spectrometry analysis.
Chicher J, Simonetti A, Kuhn L, Schaeffer L, Hammann P, Eriani G, Martin F
Proteomics. 2015 Jul;15(14):2417-25
Expression of nuclear and mitochondrial genes encoding ATP synthase is synchronized by disassembly of a multisynthetase complex.
Frechin M, Enkler L, Tetaud E, Laporte D, Senger B, Blancard C, Hammann P, Bader G, Clauder-Münster S, Steinmetz LM, Martin RP, di Rago JP, Becker HD
Mol. Cell. 2014 Dec;56(6):763-76
The effect of cold stress on the proteome of the marine bacterium Pseudomonas fluorescens BA3SM1 and its ability to cope with metal excess.
Poirier I, Kuhn L, Caplat C, Hammann P, Bertrand M
Aquat. Toxicol.. 2014 Dec;157:120-33
A method to map changes in bacterial surface composition induced by regulatory RNAs in Escherichia coli and Staphylococcus aureus.
Hammann P, Parmentier D, Cerciat M, Reimegård J, Helfer AC, Boisset S, Guillier M, Vandenesch F, Wagner EG, Romby P, Fechter P
Biochimie. 2014 Nov;106:175-9
[RsaA non-coding RNA promotes bacterial persistence and attenuates virulence in Staphylococcus aureus].
Lays C, Romilly C, Tomasini A, Caldelari I, Benito Y, Hammann P, Geissmann T, Boisset S, Romby P, Vandenesch F
Med Sci (Paris). 2014 Oct;30(10):839-41
The RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thaliana.
Lange H, Zuber H, Sement FM, Chicher J, Kuhn L, Hammann P, Brunaud V, Bérard C, Bouteiller N, Balzergue S, Aubourg S, Martin-Magniette ML, Vaucheret H, Gagliardi D
PLoS Genet.. 2014 Aug;10(8):e1004564
