Pangou E, Awal S, Meode M, Kleiss C, Cloarec M, Grandgirard E, Vivot K, Guerber L, Krupina K, Jerabkova-Roda K, Costa PJD, Alpy F, Martinet A, Lodi M, Cousido-Siah A, Wendling O, Hany R, Riché S, Daubeuf F, Gizzi P, Villa P, Nominé Y, Tomasetto C, Bonnet D, Sumara I

EMBO Mol Med. 2026 09 22;:

Sorting of lysosomal enzyme and autophagy are regulated by the GGA1-induced TGN lipid scrambling.

Takahashi K, Tomishige N, Abe M, Šolinc G, Rae J, Yamaji T, Przybilla F, Richert L, Humbert N, Uemura T, Wollert T, Waguri S, Hanada K, Sako Y, Anderluh G, Parton RG, Mély Y, Tomasetto C, Alpy F, Kobayashi T

Sci Adv. 2026 08 28;12(35):eaec4519

High-fat, low-carb diet reduces tumor growth and induces liver metabolism remodeling in a breast cancer mouse model.

Charlot A, Bringolf A, Mallard J, Jaulin A, Crouchet E, Duteil D, Alpy F, Tomasetto CL, Baumert T, Zoll J

Am J Physiol Cell Physiol. 2026 06 16;:

STARD3 regulates lysosome positioning and contacts via a GSK3-controlled phosphorylation switch.

Eichler J, Wendling C, Huver S, Zouiouich M, Hanss V, Cardinal A, Fimbel V, Birck C, McEwen AG, Knorr C, Fromental-Ramain C, Boutry M, Chenard MP, Drin G, Tomasetto C, Alpy F

EMBO J. 2026 02 25;:

In vitro methods for studying protein-lipid droplet interactions.

Eichler J, Tomasetto C, Drin G, Alpy F

Methods Enzymol. 2026 02 16;727:93-121

Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin.

Raymond JH, Aktary Z, Pouteaux M, Petit V, Luciani F, Wehbe M, Gizzi P, Bourban C, Decaudin D, Nemati F, Martianov I, Davidson I, Tomasetto CL, White RM, Mahuteau-Betzer F, Vergier B, Larue L, Delmas V

Nature. 2025 06 11;:

Mammary tumor development induces perturbation of liver glucose metabolism with inflammation and fibrosis.

Charlot A, Bringolf A, Mallard J, Jaulin A, Crouchet E, Charles AL, Duteil D, Alpy F, Tomasetto CL, Baumert TF, Zoll J

Am J Physiol Endocrinol Metab. 2025 03 19;:

Methods for Visualizing and Quantifying Cholesterol Distribution in Mammalian Cells Using Filipin and D4 Probes.

Eichler J, Huver S, Knorr CJ, Wendling C, Kobayashi T, Tomasetto C, Alpy F

Methods Mol Biol. 2025 ;2888:101-118

MMP-11 expression in early luminal breast cancer: associations with clinical, MRI, pathological characteristics, and disease-free survival.

Molière S, Lodi M, Leblanc S, Gressel A, Mathelin C, Alpy F, Chenard MP, Tomasetto C

BMC Cancer. 2024 03 4;24(1):295

Fast Ultrasound Scanning is a Rapid, Sensitive, Precise and Cost-Effective Method to Monitor Tumor Grafts in Mice.

Molière S, Martinet A, Jaulin A, Lodi M, Chamaraux-Tran TN, Alpy F, Bierry G, Tomasetto C

J Mammary Gland Biol Neoplasia. 2024 01 30;29(1):2

Differential formation of stress-granules in radiosensitive and radioresistant HNSCC cells.

Louati S, Wozny AS, Malesys C, Daguenet E, Ladjohounlou R, Alphonse G, Tomasetto C, Magné N, Lafrasse CR

Int J Radiat Oncol Biol Phys. 2023 08 22;:

Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Metabolism: Insights into Health and Disease.

Molière S, Jaulin A, Tomasetto CL, Dali-Youcef N

Int J Mol Sci. 2023 06 26;24(13):

STARD3: A New Biomarker in HER2-Positive Breast Cancer.

Lodi M, Voilquin L, Alpy F, Molière S, Reix N, Mathelin C, Chenard MP, Tomasetto CL

Cancers (Basel). 2023 01 5;15(2):

CLDN1 Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy.

Lemesle M, Geoffroy M, Alpy F, Tomasetto CL, Kuntz S, Grillier-Vuissoz I

Cancers (Basel). 2022 10 14;14(20):

MOSPD2 is an endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis.

Zouiouich M, Di Mattia T, Martinet A, Eichler J, Wendling C, Tomishige N, Grandgirard E, Fuggetta N, Fromental-Ramain C, Mizzon G, Dumesnil C, Carpentier M, Reina-San-Martin B, Mathelin C, Schwab Y, Thiam AR, Kobayashi T, Drin G, Tomasetto C, Alpy F

J Cell Biol. 2022 Jun 6;221(6):

Lipid Intake and Breast Cancer Risk: Is There a Link? A New Focus and Meta-Analysis.

Lodi M, Kiehl A, Qu FL, Gabriele V, Tomasetto C, Mathelin C

Eur J Breast Health. 2022 Apr;18(2):108-126

In Situ Artificial Contact Sites (ISACS) between synthetic and endogenous organelle membranes allow for quantification of protein tethering activities.

Milanini J, Magdeleine M, Fuggetta N, Ikhlef S, Brau F, Abelanet S, Alpy F, Tomasetto C, Drin G

J Biol Chem. 2022 Feb 26;:101780

Metabolomic Impact of Lidocaine on a Triple Negative Breast Cancer Cell Line.

Chamaraux-Tran TN, Muller M, Pottecher J, Diemunsch PA, Tomasetto C, Namer IJ, Dali-Youcef N

Front Pharmacol. 2022 ;13:821779

Wnt5a Promotes Lysosomal Cholesterol Egress and Protects Against Atherosclerosis.

Awan S, Lambert M, Imtiaz A, Alpy F, Tomasetto C, Oulad-Abdelghani M, Schaeffer C, Moritz C, Julien-David D, Najib S, Martinez LO, Matz RL, Collet X, Silva-Rojas R, Böhm J, Herz J, Terrand J, Boucher P

Circ Res. 2021 Dec 10;:

Ghrelin Gene Deletion Alters Pulsatile Growth Hormone Secretion in Adult Female Mice.

Hassouna R, Fernandez G, Lebrun N, Fiquet O, Roelfsema F, Labarthe A, Zizzari P, Tomasetto C, Epelbaum J, Viltart O, Chauveau C, Perello M, Tolle V

Front Endocrinol (Lausanne). 2021 ;12:754522

FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts.

Di Mattia T, Martinet A, Ikhlef S, McEwen AG, Nominé Y, Wendling C, Poussin-Courmontagne P, Voilquin L, Eberling P, Ruffenach F, Cavarelli J, Slee J, Levine TP, Drin G, Tomasetto C, Alpy F

EMBO J. 2020 Oct 30;:e104369

Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR.

Tan B, Jaulin A, Bund C, Outilaft H, Wendling C, Chenard MP, Alpy F, Cicek AE, Namer IJ, Tomasetto C, Dali-Youcef N

Cancers (Basel). 2020 Aug 20;12(9):

Interleukin-32 Contributes to Human Nonalcoholic Fatty Liver Disease and Insulin Resistance.

Dali-Youcef N, Vix M, Costantino F, El-Saghire H, Lhermitte B, Callari C, D'Agostino J, Perretta S, Paveliu S, Gualtierotti M, Dumeny E, Oudot MA, Jaulin A, Dembélé D, Zeisel MB, Tomasetto C, Baumert TF, Doffoël M

Hepatol Commun. 2019 Sep;3(9):1205-1220

Probiotics Upregulate Trefoil Factors and Downregulate Pepsinogen in the Mouse Stomach.

Khoder G, Al-Yassir F, Al Menhali A, Saseedharan P, Sugathan S, Tomasetto C, Karam SM

Int J Mol Sci. 2019 Aug 10;20(16):

Faraway, so close! Functions of Endoplasmic reticulum-Endosome contacts.

Di Mattia T, Tomasetto C, Alpy F

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jun 25;:

Intracellular and Plasma Membrane Cholesterol Labeling and Quantification Using Filipin and GFP-D4.

Wilhelm LP, Voilquin L, Kobayashi T, Tomasetto C, Alpy F

Methods Mol. Biol.. 2019 ;1949:137-152

[MOSPD2, an inter-organelle connector].

Di Mattia T, Tomasetto C, Alpy F

Med Sci (Paris). 2019 Jan;35(1):23-25

A novel machine learning-derived decision tree including uPA/PAI-1 for breast cancer care.

Reix N, Lodi M, Jankowski S, Molière S, Luporsi E, Leblanc S, Scheer L, Ibnouhsein I, Benabu JC, Gabriele V, Guggiola A, Lessinger JM, Chenard MP, Alpy F, Bellocq JP, Neuberger K, Tomasetto C, Mathelin C

Clin. Chem. Lab. Med.. 2018 Dec 20;:

Ghrelin knockout mice display defective skeletal muscle regeneration and impaired satellite cell self-renewal.

Angelino E, Reano S, Bollo A, Ferrara M, De Feudis M, Sustova H, Agosti E, Clerici S, Prodam F, Tomasetto CL, Graziani A, Filigheddu N

Endocrine. 2018 10;62(1):129-135

Why and How Should We Improve Breast Cancer Management in Elderly Women?

Lodi M, Lodi A, Reix N, Tomasetto C, Mathelin C

Eur J Breast Health. 2018 Jul;14(3):132-133

Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites.

Di Mattia T, Wilhelm LP, Ikhlef S, Wendling C, Spehner D, Nominé Y, Giordano F, Mathelin C, Drin G, Tomasetto C, Alpy F

EMBO Rep.. 2018 Jun 1;:

Antitumor Effects of Lidocaine on Human Breast Cancer Cells: An and Experimental Trial.

Chamaraux-Tran TN, Mathelin C, Aprahamian M, Joshi GP, Tomasetto C, Diemunsch P, Akladios C

Anticancer Res.. 2018 01;38(1):95-105

Breast cancer in elderly women and altered clinico-pathological characteristics: a systematic review.

Lodi M, Scheer L, Reix N, Heitz D, Carin AJ, Thiébaut N, Neuberger K, Tomasetto C, Mathelin C

Breast Cancer Res. Treat.. 2017 Aug;:

STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites.

Wilhelm LP, Wendling C, Védie B, Kobayashi T, Chenard MP, Tomasetto C, Drin G, Alpy F

EMBO J.. 2017 Apr;:

Combination of Selective Immunoassays and Mass Spectrometry to Characterize Preproghrelin-Derived Peptides in Mouse Tissues.

Hassouna R, Grouselle D, Chiappetta G, Lipecka J, Fiquet O, Tomasetto C, Vinh J, Epelbaum J, Tolle V

Front Neurosci. 2017 ;11:211

A prospective study to assess the clinical utility of serum HER2 extracellular domain in breast cancer with HER2 overexpression.

Reix N, Malina C, Chenard MP, Bellocq JP, Delpous S, Molière S, Sevrin A, Neuberger K, Tomasetto C, Mathelin C

Breast Cancer Res. Treat.. 2016 Nov;160(2):249-259

Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.

Dali-Youcef N, Hnia K, Blaise S, Messaddeq N, Blanc S, Postic C, Valet P, Tomasetto C, Rio MC

Sci Rep. 2016 Apr;6:25140

Touché! STARD3 and STARD3NL tether the ER to endosomes.

Wilhelm LP, Tomasetto C, Alpy F

Biochem. Soc. Trans.. 2016 Apr;44(2):493-8

[Trisomy 21 and breast cancer: A genetic abnormality which protects against breast cancer?].

Martel-Billard C, Cordier C, Tomasetto C, Jégu J, Mathelin C

Gynecol Obstet Fertil. 2016 Apr;44(4):211-7

Local adipocyte cancer cell paracrine loop: can "sick fat" be more detrimental?

Rio MC, Dali-Youcef N, Tomasetto C

Horm Mol Biol Clin Investig. 2015 Jan;21(1):43-56

Overexpression of MLN51 triggers P-body disassembly and formation of a new type of RNA granules.

Cougot N, Daguenet E, Baguet A, Cavalier A, Thomas D, Bellaud P, Fautrel A, Godey F, Bertrand E, Tomasetto C, Gillet R

J. Cell. Sci.. 2014 Nov;127(Pt 21):4692-701

Functional relationship between matrix metalloproteinase-11 and matrix metalloproteinase-14.

Buache E, Thai R, Wendling C, Alpy F, Page A, Chenard MP, Dive V, Ruff M, Dejaegere A, Tomasetto C, Rio MC

Cancer Med. 2014 Oct;3(5):1197-210

An early reduction in GH peak amplitude in preproghrelin-deficient male mice has a minor impact on linear growth.

Hassouna R, Zizzari P, Tomasetto C, Veldhuis JD, Fiquet O, Labarthe A, Cognet J, Steyn F, Chen C, Epelbaum J, Tolle V

Endocrinology. 2014 Sep;155(9):3561-71

[Legal value of the recomendations of good practice: example for breast cancer hormonotherapy].

Delpous S, Benhessa G, Bilalis A, Tomasetto C, Mathelin C

Bull Cancer. 2014 Mar;101(3):283-94

START ships lipids across interorganelle space.

Alpy F, Tomasetto C

Biochimie. 2014 Jan;96:85-95

The phosphoinositide-binding protein TRAF4 modulates tight junction stability and migration of cancer cells.

Rousseau A, Wilhelm LP, Tomasetto C, Alpy F

Tissue Barriers. 2014 Aug 8;2(4):e975597

[TRAF4, a multifaceted protein involved in carcinoma progression].

Rousseau A, Tomasetto C, Alpy F

Biol Aujourdhui. 2014;208(4):299-310

STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.

Alpy F, Rousseau A, Schwab Y, Legueux F, Stoll I, Wendling C, Spiegelhalter C, Kessler P, Mathelin C, Rio MC, Levine TP, Tomasetto C

J Cell Sci. 2013 Dec 1;126(Pt 23):5500-12

TRAF4 is a novel phosphoinositide-binding protein modulating tight junctions and favoring cell migration.

Rousseau A, McEwen AG, Poussin-Courmontagne P, Rognan D, Nomine Y, Rio MC, Tomasetto C, Alpy F

PLoS Biol. 2013 Dec;11(12):e1001726

EJC core component MLN51 interacts with eIF3 and activates translation.

Chazal PE, Daguenet E, Wendling C, Ulryck N, Tomasetto C, Sargueil B, Le Hir H

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5903-8

Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly.

Barbosa I, Haque N, Fiorini F, Barrandon C, Tomasetto C, Blanchette M, Le Hir H

Nat Struct Mol Biol. 2012 Oct;19(10):983-90

Inhibition of cyclooxygenase-2 causes regression of gastric adenomas in trefoil factor 1 deficient mice.

Thiel A, Narko K, Heinonen M, Hemmes A, Tomasetto C, Rio MC, Haglund C, Makela TP, Ristimaki A

Int J Cancer. 2012 Sep 1;131(5):1032-41

Perispeckles are major assembly sites for the exon junction core complex.

Daguenet E, Baguet A, Degot S, Schmidt U, Alpy F, Wendling C, Spiegelhalter C, Kessler P, Rio MC, Le Hir H, Bertrand E, Tomasetto C

Mol Biol Cell. 2012 May;23(9):1765-82

In vivo evidence that TRAF4 is required for central nervous system myelin homeostasis.

Blaise S, Kneib M, Rousseau A, Gambino F, Chenard MP, Messadeq N, Muckenstrum M, Alpy F, Tomasetto C, Humeau Y, Rio MC

PLoS One. 2012;7(2):e30917

Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice.

Buache E, Etique N, Alpy F, Stoll I, Muckensturm M, Reina-San-Martin B, Chenard MP, Tomasetto C, Rio MC

Oncogene. 2011 Jul 21;30(29):3261-73

Inhibition of gastric carcinogenesis by the hormone gastrin is mediated by suppression of TFF1 epigenetic silencing.

Tomita H, Takaishi S, Menheniott TR, Yang X, Shibata W, Jin G, Betz KS, Kawakami K, Minamoto T, Tomasetto C, Rio MC, Lerkowit N, Varro A, Giraud AS, Wang TC

Gastroenterology. 2011 Mar;140(3):879-91

Matrix metalloproteinase 11/stromelysin-3 exerts both activator and repressor functions during the hematogenous metastatic process in mice.

Brasse D, Mathelin C, Leroux K, Chenard MP, Blaise S, Stoll I, Tomasetto C, Rio MC

Int J Cancer. 2010 Sep 1;127(6):1347-55.

Methyl donor deficiency affects fetal programming of gastric ghrelin cell organization and function in the rat.

Bossenmeyer-Pourie C, Blaise S, Pourie G, Tomasetto C, Audonnet S, Ortiou S, Koziel V, Rio MC, Daval JL, Gueant JL, Beck B

Am J Pathol. 2010 Jan;176(1):270-7

Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12.

Thuaud F, Bernard Y, Turkeri G, Dirr R, Aubert G, Cresteil T, Baguet A, Tomasetto C, Svitkin Y, Sonenberg N, Nebigil CG, Desaubry L

J Med Chem. 2009 Aug 27;52(16):5176-87.

The potential of ghrelin as a prokinetic.

Poitras P, Tomasetto C

Regul Pept. 2009 Jun 5;155(1-3):24-7

Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.

Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, Mercier I, Flomenberg N, Frank PG, Pestell RG, Lisanti MP

Am J Pathol. 2009 May;174(5):1650-62.