Pr BERNARD Alain

Measuring performance trajectories in lung cancer surgery: a longitudinal study using the French national hospital database from 2020 to 2024.

Bernard A, Cottenet J, Tubert-Bitter P, Quantin C

BMJ Health Care Inform. 2026 06 22;33(1):

Reducing Bias in the Evaluation of Robotic Surgery for Lung Cancer Through Machine Learning.

Bernard A, Cottenet J, Tubert-Bitter P, Quantin C

Cancers (Basel). 2025 10 17;17(20):

The intrinsic expression of NLRP3 in Th17 cells promotes their protumor activity and conversion into Tregs.

Accogli T, Hibos C, Milian L, Geindreau M, Richard C, Humblin E, Mary R, Chevrier S, Jacquin E, Bernard A, Chalmin F, Paul C, Ryffel B, Apetoh L, Boidot R, Bruchard M, Ghiringhelli F, Vegran F

Cell Mol Immunol. 2025 04 7;:

Evaluation of the Quality of Results of Lung Cancer Surgery in France Using the PMSI National Database.

Bernard A, Cottenet J, Quantin C

Cancers (Basel). 2025 02 11;17(4):

Evaluation of the Learning Curve Threshold in Robot-Assisted Lung Cancer Surgery: A Nationwide Population-Based Study.

Pages PB, Cottenet J, Madelaine L, Dhérissard F, Abou-Hanna H, Bernard A, Quantin C

Cancers (Basel). 2024 12 18;16(24):

Strengths and Weaknesses of a Ten Year Nationwide Survey on Carotid Procedures in France.

Steinmetz E, Bernard A, Quantin C

Eur J Vasc Endovasc Surg. 2024 12 18;:

Stroke and Mortality Following Carotid Endarterectomy or Carotid Artery Stenting: A 10 Year Nationwide Study in France.

Steinmetz E, Cottenet J, Mariet AS, Morin L, Bernard A, Béjot Y, Quantin C

Eur J Vasc Endovasc Surg. 2024 10 25;:

[Observational studies to evaluate robotic-assisted lung cancer surgery?].

Bernard A

Rev Mal Respir. 2024 08 28;:

Is the Validity of Logistic Regression Models Developed with a National Hospital Database Inferior to Models Developed from Clinical Databases to Analyze Surgical Lung Cancers?

Bernard A, Cottenet J, Quantin C

Cancers (Basel). 2024 02 9;16(4):

[Complications after pulmonary segmentectomy: Impact of the surgical approach].

Moret A, Madelaine L, Hanna HA, Bernard A, Pagès PB

Rev Mal Respir. 2023 10 3;:

Does intraperitoneal mesh increase the risk of bowel obstruction? A nationwide French analysis.

Delorme T, Cottenet J, Abo-Alhassan F, Bernard A, Ortega-Deballon P, Quantin C

Hernia. 2023 09 28;:

Comparative Evaluation of Two Paclitaxel-Coated Stents in an Experimental Setting.

Pouhin A, Coscas R, Crespy V, Poupardin O, Pais-De-Barros JP, Bouchot O, Bernard A, Steinmetz E

J Endovasc Ther. 2023 09 20;:15266028231198033

Medico-economic impact of thoracoscopy versus thoracotomy in lung cancer: multicentre randomised controlled trial (Lungsco01).

Soilly AL, Aho Glélé LS, Bernard A, Abou Hanna H, Filaire M, Magdaleinat P, Marty-Ané C, Tronc F, Grima R, Baste JM, Thomas PA, Richard De Latour B, Pforr A, Pagès PB

BMC Health Serv Res. 2023 09 18;23(1):1004

Mortality and failure-to-rescue major complication trends after lung cancer surgery between 2005 and 2020: a nationwide population-based study.

Bernard A, Cottenet J, Pagès PB, Quantin C

BMJ Open. 2023 09 12;13(9):e075463

Increased risk of colon cancer after acute appendicitis: a nationwide, population-based study.

Viennet M, Tapia S, Cottenet J, Bernard A, Ortega-Deballon P, Quantin C

EClinicalMedicine. 2023 09;63:102196

Diffusion of Minimally Invasive Approach for Lung Cancer Surgery in France: A Nationwide, Population-Based Retrospective Cohort Study.

Bernard A, Cottenet J, Pages PB, Quantin C

Cancers (Basel). 2023 06 22;15(13):

Pulmonary artery resection with autologous pericardial conduit to avoid pneumonectomy in lung neoplasms surgery: How to do it.

Madelaine L, Bernard A, Hanna HA, Moret A, Pagès PB

JTCVS Tech. 2023 04;18:145-147

Optimal Timing of Coronary Artery Bypass Grafting in Haemodynamically Stable Patients after Myocardial Infarction.

Bernard C, Morgant MC, Jazayeri A, Perrin T, Malapert G, Jazayeri S, Bernard A, Bouchot O

Biomedicines. 2023 03 22;11(3):

Is there variation between hospitals within each region in postoperative mortality for lung cancer surgery in France? A nationwide study from 2013 to 2020.

Bernard A, Cottenet J, Pages PB, Quantin C

Front Med (Lausanne). 2023 03 14;10:1110977

Emotional Exhaustion, a Proxy for Burnout, Is Associated with Sleep Health in French Healthcare Workers without Anxiety or Depressive Symptoms: A Cross-Sectional Study.

Coelho J, Taillard J, Bernard A, Lopez R, Fond G, Boyer L, Lucas G, Alla F, Buysse DJ, Wallace ML, Verdun-Esquer C, Geoffroy PA, d'Incau E, Philip P, Micoulaud-Franchi JA

J Clin Med. 2023 02 27;12(5):

Impact of hospital volume in liver surgery on postoperative mortality and morbidity: nationwide study.

Magnin J, Bernard A, Cottenet J, Lequeu JB, Ortega-Deballon P, Quantin C, Facy O

Br J Surg. 2023 02 2;:

Is the Evaluation of Robot-Assisted Surgery Based on Sufficient Scientific Evidence?

Bernard A

J Clin Med. 2023 01 4;12(2):

Effect of Obesity among Hospitalized Cancer Patients with or without COVID-19 on a National Level.

Cottenet J, Tapia S, Arveux P, Bernard A, Dabakuyo-Yonli TS, Quantin C

Cancers (Basel). 2022 11 17;14(22):

[Comparison of mortality of lung cancer resections in France to other European countries].

Bernard A, Riviere A, Cottenet J, Madeleine L, Quantin C, Pages PB

Rev Mal Respir. 2022 08 18;:

Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects.

Mary R, Chalmin F, Accogli T, Bruchard M, Hibos C, Melin J, Truntzer C, Limagne E, Derangère V, Thibaudin M, Humblin E, Boidot R, Chevrier S, Arnould L, Richard C, Klopfenstein Q, Bernard A, Urade Y, Harker JA, Apetoh L, Ghiringhelli F, Végran F

Cancer Immunol Res. 2022 05 25;:OF1-OF17

Impact of the SARS-CoV-2 Epidemic on Lung Cancer Surgery in France: A Nationwide Study.

Pages PB, Cottenet J, Bonniaud P, Tubert-Bitter P, Piroth L, Cadranel J, Bernard A, Quantin C

Cancers (Basel). 2021 Dec 14;13(24):

The Reality of Lung Cancer Paradox: The Impact of Body Mass Index on Long-Term Survival of Resected Lung Cancer. A French Nationwide Analysis from the Epithor Database.

Alifano M, Daffré E, Iannelli A, Brouchet L, Falcoz PE, Le Pimpec Barthes F, Bernard A, Pages PB, Thomas PA, Dahan M, Porcher R

Cancers (Basel). 2021 Sep 12;13(18):

[Readmissions after lung resection in France: The PMSI database].

Moret A, Madelaine L, Cottenet J, Sophie Mariet A, Quantin C, Bernard A, Pagès PB

Rev Mal Respir. 2021 Jun 23;:

Interest of anatomical segmentectomy over lobectomy for lung cancer: a nationwide study.

Berg E, Madelaine L, Baste JM, Dahan M, Thomas P, Falcoz PE, Martinod E, Bernard A, Pagès PB

J Thorac Dis. 2021 Jun;13(6):3587-3596

Detecting Hospital Outliers in Post-Pancreatectomy Care Using Funnel Plots from 2009-2018 Based on Nationwide Medico-Administrative Data.

Bernard A, Cottenet J, Aho S, Doussot A, Mariet AS, Facy O, Quantin C

World J Surg. 2021 Apr 5;:

Comparison of Cancer Patients to Non-Cancer Patients among COVID-19 Inpatients at a National Level.

Bernard A, Cottenet J, Bonniaud P, Piroth L, Arveux P, Tubert-Bitter P, Quantin C

Cancers (Basel). 2021 Mar 21;13(6):

Failure to rescue in patients with distal pancreatectomy: a nationwide analysis of 10,632 patients.

Lequeu JB, Cottenet J, Facy O, Perrin T, Bernard A, Quantin C

HPB (Oxford). 2021 Feb 8;:

The tumor microenvironment impairs Th1 IFNγ secretion through alternative splicing modifications of Irf1 pre-mRNA.

Bernard A, Hibos C, Richard C, Viltard E, Chevrier S, Lemoine S, Melin J, Humblin E, Mary R, Accogli T, Chalmin F, Bruchard M, Peixoto P, Hervouet E, Apetoh L, Ghiringhelli F, Vegran F, Boidot R

Cancer Immunol Res. 2021 Jan 8;:

Validation and update of the thoracic surgery scoring system (Thoracoscore) risk model.

Die Loucou J, Pagès PB, Falcoz PE, Thomas PA, Rivera C, Brouchet L, Baste JM, Puyraveau M, Bernard A, Dahan M

Eur J Cardiothorac Surg. 2020 Apr 1;:

Fusobacterium nucleatum bacteremia with pneumopathy in a patient receiving eculizumab: a case report.

Seibel J, Rebibou JM, Bonnot PH, Bernard A, Zanetta G, Tetu J, Legendre M

Anaerobe. 2019 Sep 9;:102099

A micro-costing evaluation of lobectomy by thoracotomy versus thoracoscopy.

Charvin M, Späth HM, Bernard A, Bertaux AC

J Thorac Dis. 2019 Apr;11(4):1233-1242

Comparison of Epithor clinical national database and medico-administrative database to identify the influence of case-mix on the estimation of hospital outliers.

Bernard A, Falcoz PE, Thomas PA, Rivera C, Brouchet L, Baste JM, Puyraveau M, Quantin C, Pages PB, Dahan M

PLoS ONE. 2019 ;14(7):e0219672

Impact of video-assisted thoracic surgery approach on postoperative mortality after lobectomy in octogenarians.

Pagès PB, Mariet AS, Madelaine L, Cottenet J, Hanna HA, Quantin C, Bernard A

J. Thorac. Cardiovasc. Surg.. 2018 Dec 11;:

A New Method for Studying Licking Behavior Determinants in Rodents: Application to Diet-Induced Obese Mice.

Dastugue A, Merlin JF, Maquart G, Bernard A, Besnard P

Obesity (Silver Spring). 2018 Oct 28;:

Is an activity volume threshold really realistic for lung cancer resection?

Bernard A, Cottenet J, Mariet AS, Quantin C, Pagès PB

J Thorac Dis. 2018 Oct;10(10):5685-5694

[Evaluation of surgical practice in the treatment of lung cancer in France from the PMSI national database].

Bernard A, Pagès PB, Mariet AS, Pforr A, Cottenet J, Quantin C

Rev Mal Respir. 2018 Oct 1;:

Does age over 80 years have to be a contraindication for lung cancer surgery-a nationwide database study.

Pagès PB, Mariet AS, Pforr A, Cottenet J, Madelaine L, Abou-Hanna H, Bernard A, Quantin C

J Thorac Dis. 2018 Aug;10(8):4764-4773

Author Correction: Obese Subjects With Specific Gustatory Papillae Microbiota and Salivary Cues Display an Impairment to Sense Lipids.

Besnard P, Christensen JE, Brignot H, Bernard A, Passilly-Degrace P, Nicklaus S, Pais de Barros JP, Collet X, Lelouvier B, Servant F, Blasco-Baque V, Verges B, Lagrost L, Feron G, Burcelin R

Sci Rep. 2018 Jun 22;8(1):9773

Obese Subjects With Specific Gustatory Papillae Microbiota and Salivary Cues Display an Impairment to Sense Lipids.

Besnard P, Christensen JE, Brignot H, Bernard A, Passilly-Degrace P, Nicklaus S, Pais de Barros JP, Collet X, Lelouvier B, Servant F, Blasco V, Verges B, Lagrost L, Feron G, Burcelin R

Sci Rep. 2018 Apr 30;8(1):6742

Adherence to the law in brain death diagnosis: A national survey.

Chambade E, Nguyen M, Bernard A, Nadji A, Bouhemad B

Anaesth Crit Care Pain Med. 2018 Feb 21;:

Did case-based payment influence surgical readmission rates in France? A retrospective study.

Vuagnat A, Yilmaz E, Roussot A, Rodwin V, Gadreau M, Bernard A, Creuzot-Garcher C, Quantin C

BMJ Open. 2018 02 1;8(2):e018164

Clinical prediction models: a fashion or a necessity in medicine?

Bernard A

J Thorac Dis. 2017 Oct;9(10):3456-3457

Exhaustive preoperative staging increases survival in resected adrenal oligometastatic non-small-cell lung cancer: a multicentre study.

De Wolf J, Bellier J, Lepimpec-Barthes F, Tronc F, Peillon C, Bernard A, Le Rochais JP, Tiffet O, Sage E, Chapelier A, Porte H

Eur J Cardiothorac Surg. 2017 Oct 1;52(4):698-703

Medicoeconomic analysis of lobectomy using thoracoscopy versus thoracotomy for lung cancer: a study protocol for a multicentre randomised controlled trial (Lungsco01).

Pagès PB, Abou Hanna H, Bertaux AC, Serge Aho LS, Magdaleinat P, Baste JM, Filaire M, de Latour R, Assouad J, Tronc F, Jayle C, Mouroux J, Thomas PA, Falcoz PE, Marty-Ané CH, Bernard A

BMJ Open. 2017 Jun;7(6):e012963

The Interest of Performing "On-Demand Chest X-rays" after Lung Resection by Minimally Invasive Surgery.

Haddad L, Bubenheim M, Bernard A, Melki J, Peillon C, Baste JM

Thorac Cardiovasc Surg. 2017 Apr;:

L-carnitine protects C2C12 cells against mitochondrial superoxide overproduction and cell death.

Le Borgne F, Ravaut G, Bernard A, Demarquoy J

World J Biol Chem. 2017 Feb;8(1):86-94

Sleeve lobectomy may provide better outcomes than pneumonectomy for non-small cell lung cancer. A decade in a nationwide study.

Pagès PB, Mordant P, Renaud S, Brouchet L, Thomas PA, Dahan M, Bernard A,

J. Thorac. Cardiovasc. Surg.. 2017 Jan;153(1):184-195.e3

[Health technology assessments by the Haute Autorité de Santé (HAS)].

Bernard A

Rev Mal Respir. 2016 Dec;33(10):835-837

[Surgery for pulmonary metastases from colorectal cancer: Predictive factors for survival].

Pagès PB, Le Pimpec-Barthes F, Bernard A

Rev Mal Respir. 2016 Dec;33(10):838-852

Comparative study for surgical management of thymectomy for non-thymomatous myasthenia gravis from the French national database EPITHOR.

Orsini B, Santelmo N, Pages PB, Baste JM, Dahan M, Bernard A, Thomas PA,

Eur J Cardiothorac Surg. 2016 Sep;50(3):418-22

Emergency and elective pulmonary surgical resection in haematological patients with invasive fungal infections: a report of 50 cases in a single centre.

Chretien ML, Legouge C, Pagès PB, Lafon I, Ferrant E, Plocque A, Favennec C, Estivalet L, Bottolier-Lemallaz E, Dalle F, Bastie JN, Bernard A, Caillot D

Clin. Microbiol. Infect.. 2016 Sep;22(9):782-787

In-hospital mortality following lung cancer resection: nationwide administrative database.

Pagès PB, Cottenet J, Mariet AS, Bernard A, Quantin C

Eur. Respir. J.. 2016 Jun;47(6):1809-17

Risk factors for survival and recurrence after lung metastasectomy.

Pagès PB, Serayssol C, Brioude G, Falcoz PE, Brouchet L, Le Pimpec-Barthes F, Thomas PA, Bernard A

J. Surg. Res.. 2016 Jun;203(2):293-300

Propensity Score Analysis Comparing Videothoracoscopic Lobectomy With Thoracotomy: A French Nationwide Study.

Pagès PB, Delpy JP, Orsini B, Gossot D, Baste JM, Thomas P, Dahan M, Bernard A,

Ann. Thorac. Surg.. 2016 Apr;101(4):1370-8

Bilobectomy for lung cancer: contemporary national early morbidity and mortality outcomes.

Thomas PA, Falcoz PE, Bernard A, Le Pimpec-Barthes F, Jougon J, Brouchet L, Massard G, Dahan M, Loundou A,

Eur J Cardiothorac Surg. 2016 Feb;49(2):e38-43; discussion e43

Time trends in surgery for lung cancer in France from 2005 to 2012: a nationwide study.

Morgant MC, Pagès PB, Orsini B, Falcoz PE, Thomas PA, Barthes Fle P, Dahan M, Bernard A,

Eur. Respir. J.. 2015 Oct;46(4):1131-9

A Predictive Score for Bronchopleural Fistula Established Using the French Database Epithor.

Pforr A, Pages PB, Baste JM, Thomas P, Falcoz PE, Lepimpec Barthes F, Dahan M, Bernard A

Ann Thorac Surg. 2015 Aug 21. pii: S0003-4975(15)01034-6

Acute and delayed toxicity of gemcitabine administered during isolated lung perfusion: a preclinical dose-escalation study in pigs.

Pagès PB, Derangere V, Bouchot O, Magnin G, Charon-Barra C, Lokiec F, Ghiringhelli F, Bernard A

Eur J Cardiothorac Surg. 2015 Aug;48(2):228-35

Surgical management of spontaneous pneumothorax: are there any prognostic factors influencing postoperative complications?

Delpy JP, Pages PB, Mordant P, Falcoz PE, Thomas P, Le Pimpec-Barthes F, Dahan M, Bernard A

Eur J Cardiothorac Surg. 2015 Jun 12. pii: ezv195.

The oral lipid sensor GPR120 is not indispensable for the orosensory detection of dietary lipids in mice.

Ancel D, Bernard A, Subramaniam S, Hirasawa A, Tsujimoto G, Hashimoto T, Passilly-Degrace P, Khan NA, Besnard P

J. Lipid Res.. 2015 Feb;56(2):369-78

Index of prolonged air leak score validation in case of video-assisted thoracoscopic surgery anatomical lung resection: results of a nationwide study based on the French national thoracic database, EPITHORdagger

Orsini B, Baste JM, Gossot D, Berthet JP, Assouad J, Dahan M, Bernard A, Thomas PA

Eur J Cardiothorac Surg. 2015 Jan 5. pii: ezu505.

Videothoracoscopy versus thoracotomy for the treatment of spontaneous pneumothorax: a propensity score analysis.

Pages PB, Delpy JP, Falcoz PE, Thomas PA, Filaire M, Le Pimpec Barthes F, Dahan M, Bernard A

Ann Thorac Surg. 2015 Jan;99(1):258-63

[Does antifungal therapy influence postoperative morbidity or long-term survival after surgical resection for pulmonary aspergilloma?].

Pages PB, Grima R, Mordant P, Grand B, Badia A, Le Pimpec-Barthes F, Bernard A, Riquet M

Rev Pneumol Clin. 2014 Dec;70(6):322-8

Isolated lung perfusion as an adjuvant treatment of colorectal cancer lung metastases: a preclinical study in a pig model.

Pages PB, Facy O, Mordant P, Ladoire S, Magnin G, Lokiec F, Ghiringhelli F, Bernard A

PLoS One. 2013;8(3):e59485

Comparison between systemic analgesia, continuous wound catheter analgesia and continuous thoracic paravertebral block: a randomised, controlled trial of postthoracotomy pain management.

Fortier S, Hanna HA, Bernard A, Girard C

Eur J Anaesthesiol. 2012 Nov;29(11):524-30

Are postoperative consequences of neoadjuvant chemotherapy for non-small cell lung cancer more severe in elderly patients?

Rivera C, Jougon J, Dahan M, Falcoz PE, Bernard A, Brouchet L

Lung Cancer. 2012 May;76(2):216-21

Surgical management and outcomes of elderly patients with early stage non-small cell lung cancer: a nested case-control study.

Rivera C, Falcoz PE, Bernard A, Thomas PA, Dahan M

Chest. 2011 Oct;140(4):874-80

Risk model of in-hospital mortality after pulmonary resection for cancer: a national database of the French Society of Thoracic and Cardiovascular Surgery (Epithor).

Bernard A, Rivera C, Pages PB, Falcoz PE, Vicaut E, Dahan M

J Thorac Cardiovasc Surg. 2011 Feb;141(2):449-58

High N-terminal pro-B-type natriuretic peptide: a biomarker of lung cancer?

Aujollet N, Meyer M, Cailliod R, Combier F, Coignet Y, Campard S, Facy O, Bernard A, Girard C

Clin Lung Cancer. 2010 Sep 1;11(5):341-5.

[How to assess new medical devices]

Bernard A, Vicaut E

J Chir (Paris). 2009 Apr;146(2):129-35

L-Carnitine Supplementation and Physical Exercise Restore Age-Associated Decline in Some Mitochondrial Functions in the Rat

Bernard A, Rigault C, Mazue F, Le Borgne F, Demarquoy J

J Gerontol A Biol Sci Med Sci. 2008 Oct;63(10):1027-33.

Analysis of risk factors for skip lymphatic metastasis and their prognostic value in operated N2 non-small-cell lung carcinoma.

Benoit L, Anusca A, Ortega-Deballon P, Cheynel N, Bernard A, Favre JP

Eur J Surg Oncol. 2006 Jun;32(5):583-7

Evaluation of respiratory muscle strength by randomized controlled trial comparing thoracoscopy, transaxillary thoracotomy, and posterolateral thoracotomy for lung biopsy.

Bernard A, Brondel L, Arnal E, Favre JP

Eur J Cardiothorac Surg. 2006 Apr;29(4):596-600

Analysis of risk factors for skip lymphatic metastasis and their prognostic value in operated N2 non-small-cell lung carcinoma.

BENOIT L, ANISORA A, ORTEGA P, DEBALLON, CHEYNEL N, BERNARD A, FAVRE JP

EJSO 2006; 32: 583-587

Use of a decision analysis model to assess the medicoeconomic implications of FDG PET imaging in diagnosing a solitary pulmonary nodule.

Lejeune C, Al Zahouri K, Woronoff-Lemsi MC, Arveux P, Bernard A, Binquet C, Guillemin F

Eur J Health Econ. 2005 Sep;6(3):203-14.

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