Fiche personne
Coordonnées
EA7506-Biospectroscopie Translationnelle (BioSpecT)
UFR Pharmacie
Université de Reims Champagne-Ardenne
51 rue Cognacq-Jay
51096 REIMS Cedex
03 26 91 81 28
Territoire
Champagne-Ardenne
Statut
Enseignant-Chercheur
Affiliation
Équipes/plateformes
EA 7506 - Equipe "BioSpectroscopie Translationnelle (BioSpecT)"
Recherche
Expertises :
- Recherche:Biophysique
- Recherche:Imagerie
Projets
Mapping of lipids transferred from tumor surrounding adipocytes into breast cancer cells by coherent Raman imaging : spatio-temporal characterisation and regulation by obesity
2020 - Porteur du projet : Pr PIOT Olivier
Infrared spectral diagnosis for predictive cancer medicine: application to the early diagnosis and prognosis of pre-invasive bronchial intraepithelial lesions
2013 - Porteur du projet : Pr PIOT Olivier
Publications
Assessment of spectral variability encountered during FTIR analysis of fresh urine.
Sarkees E, Vuiblet V, Piot O
Talanta. 2025 07 28;297(Pt A):128650
Ex vivo spectroscopic characterisation of the biological activity of pancreatic cyst fluid.
Bouzerda O, Kane LE, Mellotte GS, Ryan BM, Maher SG, Piot O, Meade AD
Analyst. 2025 06 20;:
Evaluation of the diagnostic potential of Fourier transform-infrared spectroscopy on urine for urothelial bladder cancer: an in-hospital field study.
Sarkees E, Taha F, Oudahmane I, Vuiblet V, Larré S, Piot O
Spectrochim Acta A Mol Biomol Spectrosc. 2025 04 19;339:126274
Exploring the potential of Fourier transform-infrared spectroscopy of urine for non-invasive monitoring of inflammation associated with a kidney transplant.
Sarkees E, Vuiblet V, Taha F, Piot O
Analyst. 2025 03 12;:
Tissue analysis by vibrational spectroscopy in Hirschsprung disease: feasibility and potential as a new intraoperative tool.
Combescot C, Piot O, Untereiner V, Durlach A, Laconi F
Analyst. 2025 03 6;:
Wound Closure Promotion by Leucine-Based Pseudo-Proteins: An In Vitro Study.
Ksovreli M, Kachlishvili T, Skhvitaridze M, Nadaraia L, Goliadze R, Kamashidze L, Zurabiani K, Batsatsashvili T, Kvachantiradze N, Gverdtsiteli M, Kantaria T, Piot O, Courageot MP, Terryn C, Tchelidze P, Katsarava R, Kulikova N
Int J Mol Sci. 2024 09 6;25(17):
To what extent does freezing impact the mid-infrared signature of urine? Case of patients attending urology department.
Oudahmane I, Sarkees E, Taha F, Vanmansart J, Vuiblet V, Larre S, Piot O
Spectrochim Acta A Mol Biomol Spectrosc. 2023 12 28;309:123820
Leucine-Based Pseudo-Proteins (LPPs) as Promising Biomaterials: A Study of Cell-Supporting Properties.
Ksovreli M, Kachlishvili T, Mtiulishvili T, Dzmanashvili G, Batsatsashvili T, Zurabiani K, Tughushi D, Kantaria T, Nadaraia L, Rusishvili L, Piot O, Terryn C, Tchelidze P, Katsarava R, Kulikova N
Polymers (Basel). 2023 08 7;15(15):
Deep learning for the prediction of the chemotherapy response of metastatic colorectal cancer: comparing and combining H&E staining histopathology and infrared spectral histopathology.
Brunel B, Prada P, Slimano F, Boulagnon-Rombi C, Bouché O, Piot O
Analyst. 2023 07 19;:
Trajectory Interference for Unraveling Dynamic Biological Processes from Raman Spectral Data.
Goffin N, Buache E, Charpentier C, Lehrter V, Morjani H, Gobinet C, Piot O
Anal Chem. 2023 02 14;:
Unsupervised Feature Selection by a Genetic Algorithm for Mid-Infrared Spectral Data.
Boutegrabet W, Piot O, Guenot D, Gobinet C
Anal Chem. 2022 11 8;:
Identification of circulating biomarkers of Crohn's disease and spondyloarthritis using FTIR spectroscopy.
Prada P, Brunel B, Moulin D, Rouillon L, Netter P, Loeuille D, Slimano F, Bouche O, Peyrin-Biroulet L, Jouzeau JY, Piot O
J Biophotonics. 2022 09 16;:e202200200
New approach for hair keratin characterization: use of the confocal Raman spectroscopy to assess the effect of a thermal stress on human hair fiber.
Essendoubi M, Andre N, Granger B, Clave C, Manfait M, Thuillier I, Piot O, Ginestar J
Int J Cosmet Sci. 2022 08 2;:
Identification of Neoadjuvant Chemotherapy Response in Muscle-Invasive Bladder Cancer by Fourier-Transform Infrared Micro-Imaging.
Mazza C, Gaydou V, Eymard JC, Birembaut P, Untereiner V, Côté JF, Brocheriou I, Coeffic D, Villena P, Larré S, Vuiblet V, Piot O
Cancers (Basel). 2021 Dec 21;14(1):
Combining Raman imaging and MCR-ALS analysis for monitoring retinol permeation in human skin.
Essendoubi M, Alsamad F, Noël P, Meunier M, Scandolera A, Sandré J, Manfait M, Gobinet C, Reynaud R, Piot O
Skin Res Technol. 2021 Jun 11;:
Automatic Identification of Paraffin Pixels on FTIR Images Acquired on FFPE Human Samples.
Boutegrabet W, Guenot D, Bouché O, Boulagnon-Rombi C, Marchal Bressenot A, Piot O, Gobinet C
Anal Chem. 2021 Feb 16;:
In depth investigation of collagen non-enzymatic glycation by Raman spectroscopy.
Alsamad F, Brunel B, Vuiblet V, Gillery P, Jaisson S, Piot O
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Dec 28;251:119382
New insights into Hidradenitis suppurativa diagnosis via salivary infrared biosignatures: a pilot study.
Derruau S, Gobinet C, Untereiner V, Sockalingum GD, Nassif A, Viguier M, Piot O, Lorimier S
J Biophotonics. 2020 Nov 24;:
Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study.
Guo S, Beleites C, Neugebauer U, Abalde-Cela S, Afseth NK, Alsamad F, Anand S, Araujo-Andrade C, Aškrabić S, Avci E, Baia M, Baranska M, Baria E, Batista de Carvalho LAE, de Bettignies P, Bonifacio A, Bonnier F, Brauchle EM, Byrne HJ, Chourpa I, Cicchi R, Cuisinier F, Culha M, Dahms M, David C, Duponchel L, Duraipandian S, El-Mashtoly SF, Ellis DI, Eppe G, Falgayrac G, Gamulin O, Gardner B, Gardner P, Gerwert K, Giamarellos-Bourboulis EJ, Gizurarson S, Gnyba M, Goodacre R, Grysan P, Guntinas-Lichius O, Helgadottir H, Grošev VM, Kendall C, Kiselev R, Kölbach M, Krafft C, Krishnamoorthy S, Kubryck P, Lendl B, Loza-Alvarez P, Lyng FM, Machill S, Malherbe C, Marro M, Marques MPM, Matuszyk E, Morasso CF, Moreau M, Muhamadali H, Mussi V, Notingher I, Pacia MZ, Pavone FS, Penel G, Petersen D, Piot O, Rau JV, Richter M, Rybarczyk MK, Salehi H, Schenke-Layland K, Schlücker S, Schosserer M, Schütze K, Sergo V, Sinjab F, Smulko J, Sockalingum GD, Stiebing C, Stone N, Untereiner V, Vanna R, Wieland K, Popp J, Bocklitz T
Anal Chem. 2020 Nov 21;:
Vibrational Spectroscopy Saliva Profiling as Biometric Tool for Disease Diagnostics: A Systematic Literature.
Derruau S, Robinet J, Untereiner V, Piot O, Sockalingum GD, Lorimier S
Molecules. 2020 Sep 10;25(18):
Monitoring the molecular composition of live cells exposed to electric pulses via label-free optical methods.
Azan A, Grognot M, García-Sánchez T, Descamps L, Untereiner V, Piot O, Gallot G, Mir LM
Sci Rep. 2020 Jun 26;10(1):10471
Towards normalization selection of Raman data in the context of protein glycation: application of validity indices to PCA processed spectra.
Fatima A, Cyril G, Vincent V, Stéphane J, Olivier P
Analyst. 2020 Feb 28;:
Surface Enhanced Raman Spectroscopy for quantitative analysis: results of a large-scale European multi-instrument interlaboratory study.
Fornasaro S, Alsamad F, Baia M, Batista de Carvalho LAE, Beleites C, Byrne HJ, Chiadò A, Chis M, Chisanga M, Daniel A, Dybas J, Eppe G, Falgayrac G, Faulds K, Gebavi H, Giorgis F, Goodacre R, Graham D, La Manna P, Laing S, Litti L, Lyng FM, Malek K, Malherbe C, Marques MPM, Meneghetti M, Mitri E, Mohaček-Grošev V, Morasso C, Muhamadali H, Musto P, Novara C, Pannico M, Penel G, Piot O, Rindzevicius T, Rusu EA, Schmidt MS, Sergo V, Sockalingum GD, Untereiner V, Vanna R, Wiercigroch E, Bonifacio A
Anal. Chem.. 2020 Feb 11;:
Implementation of a classification strategy of Raman data collected in different clinical conditions: application to the diagnosis of chronic lymphocytic leukemia.
Féré M, Gobinet C, Liu LH, Beljebbar A, Untereiner V, Gheldof D, Chollat M, Klossa J, Chatelain B, Piot O
Anal Bioanal Chem. 2019 Dec 18;:
CFTR-deficient pigs display alterations of bone microarchitecture and composition at birth.
Braux J, Jourdain ML, Guillaume C, Untereiner V, Piot O, Baehr A, Klymiuk N, Winter N, Berri M, Buzoni-Gatel D, Caballero I, Guillon A, Si-Tahar M, Jacquot J, Velard F
J. Cyst. Fibros.. 2019 Nov 28;:
New insights into spectral histopathology: infrared-based scoring of tumour aggressiveness of squamous cell lung carcinomas.
Gaydou V, Polette M, Gobinet C, Kileztky C, Angiboust JF, Birembaut P, Vuiblet V, Piot O
Chem Sci. 2019 Apr 21;10(15):4246-4258
Conformation changes in human hair keratin observed using confocal Raman spectroscopy after active ingredient application.
Essendoubi M, Meunier M, Scandolera A, Gobinet C, Manfait M, Lambert C, Auriol D, Reynaud R, Piot O
Int J Cosmet Sci. 2019 Apr 4;:
Shedding light on confounding factors likely to affect salivary infrared biosignatures.
Derruau S, Gobinet C, Mateu A, Untereiner V, Lorimier S, Piot O
Anal Bioanal Chem. 2019 Feb 16;:
Mid-infrared spectral micro-imaging of inflammatory skin lesions.
Sebiskveradze D, Bertino B, Gaydou V, Dugaret AS, Roquet M, Zugaj DE, Voegel JJ, Jeannesson P, Manfait M, Piot O
J Biophotonics. 2018 May 1;:e201700380
Comprehensive Characterization of the Interaction between Pulsed Electric Fields and Live Cells by Confocal Raman Microspectroscopy.
Azan A, Untereiner V, Descamps L, Merla C, Gobinet C, Breton M, Piot O, Mir LM
Anal. Chem.. 2017 Sep;:
Doxorubicin Drug-Eluting Embolic Chemoembolization of Hepatocellular Carcinoma: Study of Midterm Doxorubicin Delivery in Resected Liver Specimens.
D'inca H, Piot O, Diebold MD, Piardi T, Marcus C, Burde F, Sommacale D, Manfait M, Thiéfin G
J Vasc Interv Radiol. 2017 Jun;28(6):804-810
Demonstration of the Protein Involvement in Cell Electropermeabilization using Confocal Raman Microspectroscopy.
Azan A, Untereiner V, Gobinet C, Sockalingum GD, Breton M, Piot O, Mir LM
Sci Rep. 2017 Jan;7:40448
Digital de-waxing on FTIR images.
de Lima FA, Gobinet C, Sockalingum G, Garcia SB, Manfait M, Untereiner V, Piot O, Bachmann L
Analyst. 2016 Dec;:
Raman-based detection of hydroxyethyl starch in kidney allograft biopsies as a potential marker of allograft quality in kidney transplant recipients.
Vuiblet V, Fere M, Bankole E, Wynckel A, Gobinet C, Birembaut P, Piot O, Rieu P
Sci Rep. 2016 Sep;6:33045
Vibrational Analysis of Lung Tumor Cell Lines: Implementation of an Invasiveness Scale Based on the Cell Infrared Signatures.
Gaydou V, Polette M, Gobinet C, Kileztky C, Angiboust JF, Manfait M, Birembaut P, Piot O
Anal. Chem.. 2016 Sep;88(17):8459-67
Renal Graft Fibrosis and Inflammation Quantification by an Automated Fourier-Transform Infrared Imaging Technique.
Vuiblet V, Fere M, Gobinet C, Birembaut P, Piot O, Rieu P
J. Am. Soc. Nephrol.. 2016 Aug;27(8):2382-91
Fully unsupervised inter-individual IR spectral histology of paraffinized tissue sections of normal colon.
Nguyen TN, Jeannesson P, Groh A, Piot O, Guenot D, Gobinet C
J Biophotonics. 2016 May;9(5):521-32
Highlighting the impact of aging on type I collagen: label-free investigation using confocal reflectance microscopy and diffuse reflectance spectroscopy in 3D matrix model.
Guilbert M, Roig B, Terryn C, Garnotel R, Jeannesson P, Sockalingum GD, Manfait M, Perraut F, Dinten JM, Koenig A, Piot O
Oncotarget. 2016 Feb;7(8):8546-55
Human skin penetration of hyaluronic acid of different molecular weights as probed by Raman spectroscopy.
Essendoubi M, Gobinet C, Reynaud R, Angiboust JF, Manfait M, Piot O
Skin Res Technol. 2016 Feb;22(1):55-62
Cellular Cholesterol Distribution Influences Proteolytic Release of the LRP-1 Ectodomain.
Dekky B, Wahart A, Sartelet H, Féré M, Angiboust JF, Dedieu S, Piot O, Devy J, Emonard H
Front Pharmacol. 2016 ;7:25
In vivo confocal Raman microspectroscopy of the human skin: highlighting of spectral markers associated to aging via a research of correlation between Raman and biometric mechanical measurements.
Eklouh-Molinier C, Gaydou V, Froigneux E, Barlier P, Couturaud V, Manfait M, Piot O
Anal Bioanal Chem. 2015 Nov;407(27):8363-72
Contribution of Raman spectroscopy in nephrology: a candidate technique to detect hydroxyethyl starch of third generation in osmotic renal lesions.
Vuiblet V, Nguyen TT, Wynckel A, Fere M, Van-Gulick L, Untereiner V, Birembaut P, Rieu P, Piot O
Analyst. 2015 Oct 12;140(21):7382-90
Investigating the relationship between changes in collagen fiber orientation during skin aging and collagen/water interactions by polarized-FTIR microimaging.
Eklouh-Molinier C, Happillon T, Bouland N, Fichel C, Diebold MD, Angiboust JF, Manfait M, Brassart-Pasco S, Piot O
Analyst. 2015 Jun 29.
Probing in vitro ribose induced DNA-glycation using Raman microspectroscopy.
Chandra GK, Eklouh-Molinier C, Fere M, Angiboust JF, Gobinet C, Van-Gulick L, Jeannesson P, Piot O
Anal Chem. 2015 Mar 3;87(5):2655-64
Monitoring caffeine and resveratrol cutaneous permeation by confocal Raman microspectroscopy.
Tfaili S, Josse G, Angiboust JF, Manfait M, Piot O
J Biophotonics. 2014 Sep;7(9):676-81
Infrared spectral histopathology for cancer diagnosis: a novel approach for automated pattern recognition of colon adenocarcinoma.
Nallala J, Diebold MD, Gobinet C, Bouche O, Sockalingum GD, Piot O, Manfait M
Analyst. 2014 Aug 21;139(16):4005-15
Changes of skin collagen orientation associated with chronological aging as probed by polarized-FTIR micro-imaging.
Nguyen TT, Eklouh-Molinier C, Sebiskveradze D, Feru J, Terryn C, Manfait M, Brassart-Pasco S, Piot O
Analyst. 2014 May 21;139(10):2482-8
Infrared and Raman imaging for characterizing complex biological materials: a comparative morpho-spectroscopic study of colon tissue.
Nallala J, Piot O, Diebold MD, Gobinet C, Bouche O, Manfait M, Sockalingum GD
Appl Spectrosc. 2014 Jan;68(1):57-68
Raman spectroscopy: in vivo quick response code of skin physiological status.
Vyumvuhore R, Tfayli A, Piot O, Le Guillou M, Guichard N, Manfait M, Baillet-Guffroy A
J Biomed Opt. 2014;19(11):111603
Raman comparison of skin dermis of different ages: focus on spectral markers of collagen hydration.
Nguyen TT, Happillon T, Feru J, Brassart-Passco S, Angiboust JF, Manfait M, Piot O
J Raman Spectrosc. 2013 Sep;44(9):1230-7.
Infrared imaging as a cancer diagnostic tool: introducing a new concept of spectral barcodes for identifying molecular changes in colon tumors.
Nallala J, Piot O, Diebold MD, Gobinet C, Bouche O, Manfait M, Sockalingum GD
Cytometry A. 2013 Mar;83(3):294-300
Vibrational spectroscopies for the analysis of cutaneous permeation: experimental limiting factors identified in the case of caffeine penetration.
Tfaili S, Gobinet C, Josse G, Angiboust JF, Baillet A, Manfait M, Piot O
Anal Bioanal Chem. 2013 Feb;405(4):1325-32
Infrared spectral imaging as a novel approach for histopathological recognition in colon cancer diagnosis.
Nallala J, Gobinet C, Diebold MD, Untereiner V, Bouche O, Manfait M, Sockalingum GD, Piot O
J Biomed Opt. 2012 Nov;17(11):116013
Shedding light on the laser wavelength effect in Raman analysis of skin epidermises.
Tfaili S, Josse G, Gobinet C, Angiboust JF, Manfait M, Piot O
Analyst. 2012 Sep 21;137(18):4241-6
Confocal Raman microspectroscopy for skin characterization: a comparative study between human skin and pig skin.
Tfaili S, Gobinet C, Josse G, Angiboust JF, Manfait M, Piot O
Analyst. 2012 Aug 21;137(16):3673-82
Characterization of Type I and IV Collagens by Raman Microspectroscopy: Identification of Spectral Markers of the Dermo-Epidermal Junction.
Nguyen TT, Gobinet C, Feru J, Brassart-Pasco S, Manfait M, Piot O
. 2012;27(5-6):421-7.
Raman microspectroscopy detects epigenetic modifications in living Jurkat leukemic cells.
Poplineau M, Trussardi-Regnier A, Happillon T, Dufer J, Manfait M, Bernard P, Piot O, Antonicelli F
Epigenomics. 2011 Dec;3(6):785-94.
Automation of an algorithm based on fuzzy clustering for analyzing tumoral heterogeneity in human skin carcinoma tissue sections.
Sebiskveradze D, Vrabie V, Gobinet C, Durlach A, Bernard P, Ly E, Manfait M, Jeannesson P, Piot O
Lab Invest. 2011 May;91(5):799-811
[Bariatric surgery, calcium oxalate urinary stones and oxalate nephropathy].
Montagnac R, Schendel A, Vuiblet V, Peilleron B, Piot O
Nephrol Ther. 2011 Feb;7(1):38-45
Histopathological characterization of primary cutaneous melanoma using infrared microimaging: a proof-of-concept study.
Ly E, Cardot-Leccia N, Ortonne JP, Benchetrit M, Michiels JF, Manfait M, Piot O
Br J Dermatol. 2010 Jun;162(6):1316-23
IR spectral imaging of secreted mucus: a promising new tool for the histopathological recognition of human colonic adenocarcinomas.
Travo A, Piot O, Wolthuis R, Gobinet C, Manfait M, Bara J, Forgue-Lafitte ME, Jeannesson P
Histopathology. 2010 Jun;56(7):921-31
Probing tumor and peritumoral tissues in superficial and nodular basal cell carcinoma using polarized Raman microspectroscopy.
Ly E, Durlach A, Antonicelli F, Bernard P, Manfait M, Piot O
Exp Dermatol. 2010 Jan;19(1):68-73
Differential diagnosis of cutaneous carcinomas by infrared spectral micro-imaging combined with pattern recognition.
Ly E, Piot O, Durlach A, Bernard P, Manfait M
Analyst. 2009 Jun;134(6):1208-14
Digital Dewaxing of Raman Signals: Discrimination Between Nevi and Melanoma Spectra Obtained from Paraffin-Embedded Skin Biopsies
Tfayli A, Gobinet C, Vrabie V, Huez R, Manfait M, Piot O
Appl Spectrosc. 2009 May;63(5):564-70.
Preprocessing methods of Raman spectra for source extraction on biomedical samples: application on paraffin-embedded skin biopsies.
Gobinet C, Vrabie V, Manfait M, Piot O
IEEE Trans Biomed Eng. 2009 May;56(5):1371-82
Optical diagnosis of peritoneal metastases by infrared microscopic imaging.
Untereiner V, Piot O, Diebold MD, Bouche O, Scaglia E, Manfait M
Anal Bioanal Chem. 2009 Mar;393(6-7):1619-27
IR spectral imaging for histopathological characterization of xenografted human colon carcinomas.
Wolthuis R, Travo A, Nicolet C, Neuville A, Gaub MP, Guenot D, Ly E, Manfait M, Jeannesson P, Piot O
Anal Chem. 2008 Nov 15;80(22):8461-9
Polarized Raman Microspectroscopy Can Reveal Structural Changes of Peritumoral Dermis in Basal Cell Carcinoma
Ly E, Piot O, Durlach A, Bernard P, Manfait M
Appl Spectrosc. 2008 Oct;62(10):1088-94.
Confocal Raman microspectroscopy on excised human skin: uncertainties in depth profiling and mathematical correction applied to dermatological drug permeation.
Tfayli A, Piot O, Manfait M
J Biophotonics. 2008 May;1(2):140-53.
Preprocessing and source separation methods for Raman spectra analysis of biomedical samples
Gobinet C, Vrabie V, Piot O, Manfait M
Irbm. 2008 Mar;29(1):13-9
Combination of FTIR spectral imaging and chemometrics for tumour detection from paraffin-embedded biopsies.
Ly E, Piot O, Wolthuis R, Durlach A, Bernard P, Manfait M
Analyst. 2008 Feb;133(2):197-205
Follow-up of drug permeation through excised human skin with confocal Raman microspectroscopy.
Tfayli A, Piot O, Pitre F, Manfait M
Eur Biophys J. 2007 Nov;36(8):1049-58
Molecular characterization of reconstructed skin model by Raman microspectroscopy: comparison with excised human skin.
Tfayli A, Piot O, Draux F, Pitre F, Manfait M
Biopolymers. 2007 Nov;87(4):261-74.
Independent component analysis of Raman spectra: Application on paraffin-embedded skin biopsies
Vrabie V, Gobinet C, Piot O, Tfayli A, Bernard P, Huez R, Manfait M
Biomed Signal Process Control. 2007 Jan;2(1):40-50
Pre-processing and source separation methods for Raman spectra analysis of biomedical samples.
Gobinet C, Vrabie V, Tfayli A, Piot O, Huez R, Manfait M
Conf Proc IEEE Eng Med Biol Soc. 2007;2007:6208-11.
Active bimorph-based tapping-mode distance control for scanning near-field optical microscopy of biological samples in liquid.
Lei FH, Huang L, Piot O, Trussardi A, Manfait M, Shang G, Troyon M
J Appl Phys. 2006 Oct 15;100(8):084317.
Discriminating nevus and melanoma on paraffin-embedded skin biopsies using FTIR microspectroscopy.
Tfayli A, Piot O, Durlach A, Bernard P, Manfait M
Biochim Biophys Acta. 2005 Aug 5;1724(3):262-9.
Changes in adsorption and permeability of mitoxantrone on plasma membrane of BCRP/MXR resistant cells.
Breuzard G, Piot O, Angiboust JF, Manfait M, Candeil L, Del Rio M, Millot JM
Biochem Biophys Res Commun. 2005 Apr 1;329(1):64-70.