Cameron DP, Jackson K, Loffreda A, Möller C, Kuzin V, Mazzocca M, Iliopoulou E, Kolbeinsdottir H, Paluda A, Pavlova E, Jagodic B, Lopez Duran BS, Lamour V, Westerlund F, Mazza D, Baranello L

Nat Commun. 2026 02 9;:

DNA topoisomerase I acts as supercoiling sensor for bacterial transcription elongation.

Vidmar V, Borde C, Bruno L, Miropolskaya N, Takacs M, Batisse C, Saint-André C, Zhu C, Espéli O, Lamour V, Weixlbaumer A

Nat Struct Mol Biol. 2025 12 1;:

DNA TOPOISOMERASE II MUTATIONS IN CANCER: STRUCTURAL IMPACT AND DRUG RESPONSE IN HIGH-GRADE SEROUS OVARIAN CARCINOMA.

Mazzoleni V, Boichard A, Lamour V

J Mol Biol. 2025 08 11;:169384

Structural basis of DNA crossover capture by DNA gyrase.

Vayssières M, Marechal N, Yun L, Lopez Duran B, Murugasamy NK, Fogg JM, Zechiedrich L, Nadal M, Lamour V

Science. 2024 04 12;384(6692):227-232

What's on the Other Side of the Gate: A Structural Perspective on DNA Gate Opening of Type IA and IIA DNA Topoisomerases.

Vidmar V, Vayssières M, Lamour V

Int J Mol Sci. 2023 02 16;24(4):

The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans.

Daiß JL, Pilsl M, Straub K, Bleckmann A, Höcherl M, Heiss FB, Abascal-Palacios G, Ramsay EP, Tlučková K, Mars JC, Fürtges T, Bruckmann A, Rudack T, Bernecky C, Lamour V, Panov K, Vannini A, Moss T, Engel C

Life Sci Alliance. 2022 11;5(11):

Structural basis for allosteric regulation of Human Topoisomerase IIα.

Vanden Broeck A, Lotz C, Drillien R, Haas L, Bedez C, Lamour V

Nat Commun. 2021 05 20;12(1):2962

Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes.

Huang SN, Michaels SA, Mitchell BB, Majdalani N, Vanden Broeck A, Canela A, Tse-Dinh YC, Lamour V, Pommier Y

Sci Adv. 2021 Mar;7(10):

The interplay between DNA topoisomerase 2α post-translational modifications and drug resistance.

Lotz C, Lamour V

Cancer Drug Resist. 2020 02 27;3(2):149-160

Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex.

Vanden Broeck A, Lotz C, Ortiz J, Lamour V

Nat Commun. 2019 Oct 30;10(1):4935

Structural Basis for DNA Gyrase Interaction with Coumermycin A1.

Vanden Broeck AP, McEwen AG, Chebaro Y, Potier N, Lamour V

J. Med. Chem.. 2019 Mar 28;:

Publisher Correction: Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain.

Bedez C, Lotz C, Batisse C, Broeck AV, Stote RH, Howard E, Pradeau-Aubreton K, Ruff M, Lamour V

Sci Rep. 2018 Jul 10;8(1):10673

Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain.

Bedez C, Lotz C, Batisse C, Broeck AV, Stote RH, Howard E, Pradeau-Aubreton K, Ruff M, Lamour V

Sci Rep. 2018 Jun 18;8(1):9272

A no-stop mutation in MAGEB4 is a possible cause of rare X-linked azoospermia and oligozoospermia in a consanguineous Turkish family.

Okutman O, Muller J, Skory V, Garnier JM, Gaucherot A, Baert Y, Lamour V, Serdarogullari M, Gultomruk M, Röpke A, Kliesch S, Herbepin V, Aknin I, Benkhalifa M, Teletin M, Bakircioglu E, Goossens E, Charlet-Berguerand N, Bahceci M, Tüttelmann F, Viville S

J. Assist. Reprod. Genet.. 2017 Apr;: