Exclusive Chemoradiotherapy With or Without Radiation Dose Escalation in Esophageal Cancer: Multicenter Phase 2/3 Randomized Trial CONCORDE (PRODIGE-26).

Fiche publication


Date publication

novembre 2021

Journal

International journal of radiation oncology, biology, physics

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BERTAUT Aurélie, Dr DROUILLARD Antoine, Pr NOEL Georges, Pr PEIFFERT Didier, Dr ROUFFIAC-THOUANT Magali, Dr BOUSTANI Jihane


Tous les auteurs :
Crehange G, M'vondo C, Bertaut A, Pereira R, Rio E, Peiffert D, Gnep K, Benezery K, Ronchin P, Noel G, Mineur L, Drouillard A, Blanc J, Rouffiac M, Boustani J

Résumé

Increasing dose of chemoradiotherapy in locally advanced esophageal cancer unsuitable for surgery has been a matter of debate in the last 2 decades. Advances in tumor staging and radiation targeting with modern imaging and IMRT should allow further testing exclusive radiation dose escalation in esophageal cancer.

Référence

Int J Radiat Oncol Biol Phys. 2021 Nov 1;111(3S):S5