Patients with Persistent Polyclonal B-Cell Lymphocytosis Share the Symptomatic Criteria of Systemic Exertion Intolerance Disease.

Fiche publication


Date publication

juillet 2021

Journal

Journal of clinical medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr FEUGIER Pierre, Dr LESESVE Jean-François, Pr BROSEUS Julien


Tous les auteurs :
Morizot R, de Korwin JD, Feugier P, Broséus J, Troussard X, Lesesve JF

Résumé

Persistent polyclonal B-cell lymphocytosis (PPBL) is a rare and still poorly understood entity, with 90% of cases occurring in female smokers. Patients often appear tired and in pain, but the clinical symptoms remain imprecise. The main risk is the development of lymphoma in some cases. To better understand the characteristics of the fatigue associated with PPBL and study its relationship with systemic exertion intolerance disease (SEID), we analyzed the symptoms in a cohort of patients with PPBL included in the French national registry.

Mots clés

chronic fatigue syndrome, myalgic encephalomyelitis, patient opinion, persistent polyclonal B-cell lymphocytosis, systemic exertion intolerance disease

Référence

J Clin Med. 2021 Jul 29;10(15):