Can the hyperthermia-mediated Heat Shock Factor (HSF) /Heat Shock Protein (HSP) 70 pathway dampen the cytokine storm during SARS-CoV-2 infection?
Fiche publication
Date publication
décembre 2020
Journal
British journal of pharmacology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GARRIDO Carmen, Pr GHIRINGHELLI François, Dr REBE Cédric
Tous les auteurs :
Rébé C, Ghiringhelli F, Garrido C
Lien Pubmed
Résumé
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major global public health problem. Infection by this virus entails many pathophysiological processes, such as a "cytokine storm", i.e. very aggressive inflammation that offers new perspectives for the management and treatment of patients. Here, we propose relevant piece of information for hyperthermia-mediated HSFs/HSP70 to be considered as one possible treatment tool.
Référence
Br J Pharmacol. 2020 Dec 11;: