A nonradiated grade II glioma that underwent delayed malignant transformation to a gliosarcoma with meningeal growth and dissemination.
Fiche publication
Date publication
novembre 2014
Journal
Journal of neurological surgery. Part A, Central European neurosurgery
Auteurs
Membres identifiés du Cancéropôle Est :
Pr TAILLANDIER Luc, Pr GAUCHOTTE Guillaume, Dr RECH Fabien
Tous les auteurs :
Rech F, Rigau V, Fabbro M, Kerr C, Gauchotte G, Taillandier L, Duffau H
Lien Pubmed
Résumé
Secondary gliosarcomas are rare tumors, especially those arising from a World Health Organization (WHO) grade II glioma not irradiated. We report a case with subtotal resection for a WHO grade II oligoastrocytoma, without adjuvant treatment, whose metaplastic transformation into gliosarcoma suddenly occurred 4 years later with meningeal dissemination. We show a favorable outcome after therapeutic management of this rare entity.
Mots clés
Astrocytoma, pathology, Brain Neoplasms, drug therapy, Female, Gliosarcoma, pathology, Humans, Meningeal Neoplasms, pathology, Middle Aged, Neoplasm Grading, Neoplasm Recurrence, Local, drug therapy, Treatment Outcome
Référence
J Neurol Surg A Cent Eur Neurosurg. 2014 Nov;75(6):485-90