Dual Diagnostic Role of 123I-MIBG Scintigraphy in Inverted-Takotsubo Pattern Cardiomyopathy.
Fiche publication
Date publication
octobre 2015
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr COTTIN Yves, Pr COCHET Alexandre
Tous les auteurs :
Humbert O, Stamboul K, Gudjoncik A, Kanoun S, Richard C, Cochet A, Cottin Y
Lien Pubmed
Résumé
We highlight the dual role of I-MIBG scintigraphy in inverted-Takotsubo pattern cardiomyopathy, the diagnosis of which is sometimes challenging: Firstly, I-MIBG scintigraphy can show myocardial sympathetic dysfunction (low I-MIBG uptake) in the hypokinetic basal segments, sparing the left ventricle apex. It is helpful in the imaging diagnosis of inverted-Takotsubo pattern cardiomyopathy and confirms that acute dysfunction of myocardial sympathetic nerve endings occurs with this cardiomyopathy. Secondly, I-MIBG scintigraphy is an accurate imaging examination to detect and localize pheochromocytoma; it can help in the search for an endogenous cause of this adrenergic stress-related cardiomyopathy.
Mots clés
3-Iodobenzylguanidine, Adult, Humans, Male, Positron-Emission Tomography, Radiopharmaceuticals, Takotsubo Cardiomyopathy, diagnostic imaging
Référence
Clin Nucl Med. 2015 Oct;40(10):816-8