Anti-Saccharomyces cerevisiae Immunogloblin G and Immunoglobulin A antibodies are associated with systemic inflammation and advanced disease in hidradenitis suppurativa.
Fiche publication
Date publication
février 2020
Journal
The Journal of allergy and clinical immunology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr AUBIN François
Tous les auteurs :
Assan F, Gottlieb J, Tubach F, Lebbah S, Guigue N, Hickman G, Pape E, Madrange M, Delaporte E, Sendid B, Aubin F, Derouin F, Bretagne S, Richette P, Smahi A, Sbidian E, Bachelez H
Lien Pubmed
Résumé
This is the first prospective study showing that ASCA are biomarkers for HS, especially in severe inflammatory forms, but not in PV, supporting the contribution of a gut fungal dysbiosis to HS pathogenesis.
Mots clés
Anti-Saccharomyces Cerivisiae antibodies, Hidradenitis suppurativa, Psoriasis, dysbiosis
Référence
J. Allergy Clin. Immunol.. 2020 Feb 12;: