[Tumor microenvironment: regulatory cells and immunosuppressive cytokines].
Fiche publication
Date publication
avril 2014
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GHIRINGHELLI François, Dr BRUCHARD Mélanie
Tous les auteurs :
Bruchard M, Ghiringhelli F
Lien Pubmed
Résumé
Immunosuppression is a mechanism developed by cancer cells to help them escape the immune system. Immunosuppression involves expansion of various cell types and production of a variety of cytokines. In this review, we explore the duality of three cancer induced cell populations, regulatory T lymphocytes, Th17 lymphocytes and MDSC, and also the pleiotropic effects of several cytokines induced during cancer development.
Référence
Med Sci (Paris). 2014 Apr;30(4):429-35