Multicenter phase III randomized trial comparing laparoscopy and laparotomy for colon cancer surgery in patients older than 75 years: the CELL study, a Fédération de Recherche en Chirurgie (FRENCH) trial.
Fiche publication
Date publication
décembre 2019
Journal
BMC cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BOUCHE Olivier, Dr FACY Olivier
Tous les auteurs :
Manceau G, Brouquet A, Chaibi P, Passot G, Bouché O, Mathonnet M, Regimbeau JM, Lo Dico R, Lefèvre JH, Peschaud F, Facy O, Volpin E, Chouillard E, Beyert-Berjot L, Verny M, Karoui M, Benoist S
Lien Pubmed
Résumé
Several multicenter randomized controlled trials comparing laparoscopy and conventional open surgery for colon cancer have demonstrated that laparoscopic approach achieved the same oncological results while improving significantly early postoperative outcomes. These trials included few elderly patients, with a median age not exceeding 71 years. However, colon cancer is a disease of the elderly. More than 65% of patients operated on for colon cancer belong to this age group, and this proportion may become more pronounced in the coming years. In current practice, laparoscopy is underused in this population.
Mots clés
Colon cancer, Elderly patient, Laparoscopy, Laparotomy, Morbidity, Phase III trial, Surgery
Référence
BMC Cancer. 2019 Dec 4;19(1):1185