First case report of an adrenocortical carcinoma caused by a BRCA2 mutation.
Fiche publication
Date publication
septembre 2016
Journal
Medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MAUGARD Christine
Tous les auteurs :
El Ghorayeb N, Grunenwald S, Nolet S, Primeau V, Côté S, Maugard CM, Lacroix A, Gaboury L, Bourdeau I
Lien Pubmed
Résumé
Adrenocortical carcinoma (ACC) may rarely be a component of inherited cancer syndromes such as Li-Fraumeni syndrome and Beckwith-Wiedemann syndrome. ACC caused by a BRCA2 mutation has never been reported.
Mots clés
Adrenal Cortex Neoplasms, genetics, Adrenocortical Carcinoma, genetics, Adult, Breast Neoplasms, genetics, Female, Genes, BRCA2, Germ-Line Mutation, Heterozygote, Humans, Male, Middle Aged, Pedigree
Référence
Medicine (Baltimore). 2016 Sep;95(36):e4756