Pathology of Rotavirus-driven Multiple Organ Failure in a 16-month-old Boy.

Fiche publication


Date publication

octobre 2019

Journal

The Pediatric infectious disease journal

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CALLIER Patrick, Pr HUET Frédéric, Pr MARTIN Laurent


Tous les auteurs :
Tarris G, Belliot G, Callier P, Huet F, Martin L, de Rougemont A

Résumé

Autopsy investigation of a fatal case of rotavirus severe acute gastroenteritis and multiple organ failure in a 16-month boy with previous intrauterine growth retardation showed colocalization of nonstructural and structural rotavirus proteins within viroplasms in nephrons. This case brings new insights into extraintestinal rotavirus infection and new clues to its abilities to bind to human histo-blood group antigens.

Référence

Pediatr. Infect. Dis. J.. 2019 Oct 15;: