Prospective validation of a lymphocyte infiltration prognostic test in stage III colon cancer patients treated with adjuvant FOLFOX.
Fiche publication
Date publication
juin 2017
Journal
European journal of cancer (Oxford, England : 1990)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LEPAGE Côme, Dr BOULAGNON-ROMBI Camille
Tous les auteurs :
Emile JF, Julié C, Le Malicot K, Lepage C, Tabernero J, Mini E, Folprecht G, Van Laethem JL, Dimet S, Boulagnon-Rombi C, Allard MA, Penault-Llorca F, Bennouna J, Laurent-Puig P, Taieb J, , , , , , , , , , , , , , , , ,
Lien Pubmed
Résumé
The prognostic value of lymphocyte infiltration (LI) of colorectal carcinoma (CC) has been demonstrated by several groups. However, no validated test is currently available for clinical practice. We previously described an automated and reproducible method for testing LI and aimed to validate it for clinical use.
Mots clés
Biomarker, Colorectal carcinoma, Immune response, Prospective cohort study
Référence
Eur. J. Cancer. 2017 Jun;82:16-24