UMD-MEN1 database: an overview of the 370 MEN1 variants present in 1,676 patients from the French population.

Fiche publication


Date publication

octobre 2018

Journal

The Journal of clinical endocrinology and metabolism

Auteurs

Membres identifiés du Cancéropôle Est :
Dr GOUDET Pierre


Tous les auteurs :
Romanet P, Mohamed A, Giraud S, Odou MF, North MO, Pertuit M, Pasmant E, Coppin L, Guien C, Calender A, Borson-Chazot F, Béroud C, Goudet P, Barlier A

Résumé

Multiple Endocrine Neoplasia type 1 (MEN1) is an autosomal dominant disease caused by mutations in the MEN1 gene characterized by a broad spectrum of clinical manifestations, of which the most frequent are primary hyperparathyroidism, pituitary adenomas, and neuroendocrine tumors.

Référence

J. Clin. Endocrinol. Metab.. 2018 Oct 18;: