The sentinel node concept in endometrial cancer: histopathologic validation by serial section and immunohistochemistry.

Fiche publication


Date publication

novembre 2007

Journal

Annals of oncology : official journal of the European Society for Medical Oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr COUTANT Charles


Tous les auteurs :
Delpech Y, Cortez A, Coutant C, Callard P, Uzan S, Darai E, Barranger E

Résumé

The sentinel node (SN) is defined as the first node in the lymphatic system that drains a tumor site. If the SN is not metastatic, then all other nodes should also be disease-free. We used serial sections and immunohistochemical (IHC) staining to examine both SN and non-sentinel nodes (non-SNs).

Mots clés

Adenocarcinoma, epidemiology, Aged, Endometrial Neoplasms, epidemiology, Female, Humans, Hysteroscopy, methods, Immunohistochemistry, standards, Lymph Nodes, pathology, Lymphatic Metastasis, Magnetic Resonance Imaging, Middle Aged, Neoplasm Invasiveness, pathology, Neoplasm Staging, Prognosis, Prospective Studies, Risk Assessment, Sensitivity and Specificity, Sentinel Lymph Node Biopsy, methods, Survival Analysis

Référence

Ann. Oncol.. 2007 Nov;18(11):1799-803