Gene pathways associated with prognosis and chemotherapy sensitivity in molecular subtypes of breast cancer.
Fiche publication
Date publication
février 2011
Journal
Journal of the National Cancer Institute
Auteurs
Membres identifiés du Cancéropôle Est :
Pr COUTANT Charles
Tous les auteurs :
Iwamoto T, Bianchini G, Booser D, Qi Y, Coutant C, Shiang CY, Santarpia L, Matsuoka J, Hortobagyi GN, Symmans WF, Holmes FA, O'Shaughnessy J, Hellerstedt B, Pippen J, Andre F, Simon R, Pusztai L
Lien Pubmed
Résumé
We hypothesized that distinct biological processes might be associated with prognosis and chemotherapy sensitivity in the different types of breast cancers.
Mots clés
Adult, Aged, Antineoplastic Combined Chemotherapy Protocols, therapeutic use, Biomarkers, Tumor, metabolism, Breast Neoplasms, drug therapy, Chemotherapy, Adjuvant, Confounding Factors (Epidemiology), Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System, metabolism, Databases, Genetic, Drug Resistance, Neoplasm, drug effects, Female, GTP-Binding Proteins, antagonists & inhibitors, Gene Expression Regulation, Neoplastic, drug effects, Humans, Middle Aged, Neoadjuvant Therapy, methods, Neoplasm Staging, Predictive Value of Tests, Prognosis, Receptors, Estrogen, metabolism, Signal Transduction, drug effects, Treatment Outcome
Référence
J. Natl. Cancer Inst.. 2011 Feb;103(3):264-72