Mr LEROUGE Thierry

Fiche personne

coordonnées

IGBMC
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH

03 69 48 52 03

titi@igbmc.fr

Territoire

Alsace

Statut

Ingénieur/Technicien

affiliation

IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)

équipes/plateformes

Plateforme Service de biologie moléculaire et virus

Publications

Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA.

Herquel B, Ouararhni K, Martianov I, Le Gras S, Ye T, Keime C, Lerouge T, Jost B, Cammas F, Losson R, Davidson I

Nat Struct Mol Biol. 2013 Mar;20(3):339-46

Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha.

Khetchoumian K, Teletin M, Tisserand J, Mark M, Herquel B, Ignat M, Zucman-Rossi J, Cammas F, Lerouge T, Thibault C, Metzger D, Chambon P, Losson R

Nat. Genet.. 2007 Dec;39(12):1500-6

TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.

Khetchoumian K, Teletin M, Mark M, Lerouge T, Cerviño M, Oulad-Abdelghani M, Chambon P, Losson R

J. Biol. Chem.. 2004 Nov;279(46):48329-41

Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation.

Cammas F, Herzog M, Lerouge T, Chambon P, Losson R

Genes Dev.. 2004 Sep;18(17):2147-60

Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1 gamma gene.

Yan KP, Dollé P, Mark M, Lerouge T, Wendling O, Chambon P, Losson R

Gene. 2004 Jun;334:3-13

Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif.

Nielsen AL, Jørgensen P, Lerouge T, Cerviño M, Chambon P, Losson R

Mol. Cell. Biol.. 2004 Jun;24(12):5184-96

NSD1 is essential for early post-implantation development and has a catalytically active SET domain.

Rayasam GV, Wendling O, Angrand PO, Mark M, Niederreither K, Song L, Lerouge T, Hager GL, Chambon P, Losson R

EMBO J.. 2003 Jun;22(12):3153-63

Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha.

Nielsen AL, Sanchez C, Ichinose H, Cerviño M, Lerouge T, Chambon P, Losson R

EMBO J.. 2002 Nov;21(21):5797-806

Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells.

Buj-Bello A, Furling D, Tronchère H, Laporte J, Lerouge T, Butler-Browne GS, Mandel JL

Hum. Mol. Genet.. 2002 Sep;11(19):2297-307

Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators.

Huang N, vom Baur E, Garnier JM, Lerouge T, Vonesch JL, Lutz Y, Chambon P, Losson R

EMBO J.. 1998 Jun;17(12):3398-412

Purification of the human RARgamma ligand-binding domain and crystallization of its complex with all-trans retinoic acid.

Rochel N, Renaud JP, Ruff M, Vivat V, Granger F, Bonnier D, Lerouge T, Chambon P, Gronemeyer H, Moras D

Biochem. Biophys. Res. Commun.. 1997 Jan;230(2):293-6

A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms.

Meyer ME, Quirin-Stricker C, Lerouge T, Bocquel MT, Gronemeyer H

J. Biol. Chem.. 1992 May;267(15):10882-7

Mechanisms of antihormone action.

Gronemeyer H, Benhamou B, Berry M, Bocquel MT, Gofflo D, Garcia T, Lerouge T, Metzger D, Meyer ME, Tora L

J. Steroid Biochem. Mol. Biol.. 1992 Mar;41(3-8):217-21

A single amino acid that determines the sensitivity of progesterone receptors to RU486.

Benhamou B, Garcia T, Lerouge T, Vergezac A, Gofflo D, Bigogne C, Chambon P, Gronemeyer H

Science. 1992 Jan;255(5041):206-9

Characterization of multiple mRNAs originating from the chicken progesterone receptor gene. Evidence for a specific transcript encoding form A.

Jeltsch JM, Turcotte B, Garnier JM, Lerouge T, Krozowski Z, Gronemeyer H, Chambon P

J. Biol. Chem.. 1990 Mar;265(7):3967-74

The chicken progesterone receptor: sequence, expression and functional analysis.

Gronemeyer H, Turcotte B, Quirin-Stricker C, Bocquel MT, Meyer ME, Krozowski Z, Jeltsch JM, Lerouge T, Garnier JM, Chambon P

EMBO J.. 1987 Dec;6(13):3985-94