Dr JACOB Christophe

Fiche personne

coordonnées

Laboratoire IMoPA
UMR 7365 CNRS-UL
Biopôle de l'Université de Lorraine
Campus Biologie-Santé, Faculté de Médecine
9 avenue de la Forêt de Haye
CS 50184
54505 VANDOEUVRE-LES-NANCY

03 72 74 66 61

christophe.jacob@univ-lorraine.fr

Territoire

Lorraine

Statut

Enseignant-Chercheur

affiliation

Université de Lorraine (UL)

équipes/plateformes

Equipe UMR 7365 IMoPA - Equipe "Enzymologie Moléculaire & Structurale (EMS)

Publications

Sesquiterpenes of the ectomycorrhizal fungus Pisolithus microcarpus alter root growth and promote host colonization.

Plett JM, Wojtalewicz D, Plett KL, Collin S, Kohler A, Jacob C, Martin F

Mycorrhiza. 2024 03 5;:

Decrypting the programming of β-methylation in virginiamycin M biosynthesis.

Collin S, Cox RJ, Paris C, Jacob C, Chagot B, Weissman KJ, Gruez A

Nat Commun. 2023 03 10;14(1):1327

Gelatin implant in the treatment of open-angle glaucoma: Safety and efficacy in real-life conditions.

About C, Maalouf J, Jacob C, Jolly C, Nisse YE, Demore B

J Fr Ophtalmol. 2022 12 21;:

Engineering the stambomycin modular polyketide synthase yields 37-membered mini-stambomycins.

Su L, Hôtel L, Paris C, Chepkirui C, Brachmann AO, Piel J, Jacob C, Aigle B, Weissman KJ

Nat Commun. 2022 Jan 26;13(1):515

Engineering Modular Polyketide Biosynthesis in Streptomyces Using CRISPR/Cas: A Practical Guide.

Massicard JM, Su L, Jacob C, Weissman KJ

Methods Mol Biol. 2022 ;2489:173-200

Manipulating polyketide stereochemistry by exchange of polyketide synthase modules.

Massicard JM, Soligot C, Weissman KJ, Jacob C

Chem. Commun. (Camb.). 2020 Sep 23;:

Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis.

Dorival J, Risser F, Jacob C, Collin S, Dräger G, Paris C, Chagot B, Kirschning A, Gruez A, Weissman KJ

Nat Commun. 2018 Sep 28;9(1):3998

Unpackaging the Roles of Streptomyces Natural Products.

Jacob C, Weissman KJ

Cell Chem Biol. 2017 Oct 19;24(10):1194-1195

Characterization of Intersubunit Communication in the Virginiamycin trans-Acyl Transferase Polyketide Synthase.

Dorival J, Annaval T, Risser F, Collin S, Roblin P, Jacob C, Gruez A, Chagot B, Weissman KJ

J. Am. Chem. Soc.. 2016 Mar;138(12):4155-67

Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry.

Annaval T, Paris C, Leadlay PF, Jacob C, Weissman KJ

Chembiochem. 2015 Jun 15;16(9):1357-64

Biochemical and functional characterization of a periplasmic disulfide oxidoreductase from Neisseria meningitidis essential for meningococcal viability.

Gand A, Selme-Roussel L, Collin S, Branlant G, Jacob C, Boschi-Muller S

Biochem J. 2015 Jun 1;468(2):271-82

Evidence that glutathione and the glutathione system efficiently recycle 1-cys sulfiredoxin in vivo.

Boukhenouna S, Mazon H, Branlant G, Jacob C, Toledano MB, Rahuel-Clermont S

Antioxid Redox Signal. 2015 Mar 20;22(9):731-43

Thioredoxin 2 from Escherichia coli is not involved in vivo in the recycling process of methionine sulfoxide reductase activities.

Jacob C, Kriznik A, Boschi-Muller S, Branlant G

FEBS Lett. 2011 Jun 23;585(12):1905-9

Formation of the complex between DsbD and PilB N-terminal domains from Neisseria meningitidis necessitates an adaptability of nDsbD.

Quinternet M, Tsan P, Selme-Roussel L, Jacob C, Boschi-Muller S, Branlant G, Cung MT

Structure. 2009 Jul 15;17(7):1024-33.

Solution structure and backbone dynamics of the cysteine 103 to serine mutant of the N-terminal domain of DsbD from Neisseria meningitidis.

Quinternet M, Tsan P, Selme L, Beaufils C, Jacob C, Boschi-Muller S, Averlant-Petit MC, Branlant G, Cung MT

Biochemistry. 2008 Dec 2;47(48):12710-20.

1H, 13C, and 15N resonance assignment of the C103S mutant of the N-terminal domain of DsbD from Neisseria meningitidis.

Quinternet M, Selme L, Beaufils C, Tsan P, Jacob C, Boschi-Muller S, Averlant-Petit MC, Branlant G, Cung MT

Biomol NMR Assign. 2008 Jun;2(1):85-7