Détail d'une personne de l'annuaire - fr | Cancéropôle Est, la recherche innovante dans la lutte contre le cancer

Development and therapeutic potential of DNA-dependent protein kinase inhibitors.

Hui Z, Deng H, Zhang X, Garrido C, Lirussi F, Ye XY, Xie T, Liu ZQ

Bioorg Chem. 2024 06 29;150:107608

A pivotal role for the IL-1β and the inflammasome in preterm labor.

Lopez TE, Zhang H, Bouysse E, Neiers F, Ye XY, Garrido C, Wendremaire M, Lirussi F

Sci Rep. 2024 02 20;14(1):4234

Recent progress in discovery of novel AAK1 inhibitors: from pain therapy to potential anti-viral agents.

Yuan YH, Mao ND, Duan JL, Zhang H, Garrido C, Lirussi F, Gao Y, Xie T, Ye XY

J Enzyme Inhib Med Chem. 2023 12;38(1):2279906

Structure-activity analysis suggests an olfactory function for the unique antennal delta glutathione transferase of Apis mellifera.

Schwartz M, Boichot V, Muradova M, Fournier P, Senet P, Nicolai A, Canon F, Lirussi F, Ladeira R, Maibeche M, Chertemps T, Aubert E, Didierjean C, Neiers F

FEBS Lett. 2023 11 7;:

Characterization of human oxidoreductases involved in aldehyde odorant metabolism.

Boichot V, Menetrier F, Saliou JM, Lirussi F, Canon F, Folia M, Heydel JM, Hummel T, Menzel S, Steinke M, Hackenberg S, Schwartz M, Neiers F

Sci Rep. 2023 03 25;13(1):4876

Role of Insect and Mammal Glutathione Transferases in Chemoperception.

Schwartz M, Boichot V, Fraichard S, Muradova M, Senet P, Nicolai A, Lirussi F, Bas M, Canon F, Heydel JM, Neiers F

Biomolecules. 2023 02 8;13(2):

Plasma membrane lipid bilayer is druggable: Selective delivery of gemcitabine-squalene nano-medicine to cancer cells.

Lirussi F, Pyrshev K, Yesylevskyy S, Rivel T, Lopez T, Coppens E, Mura S, Couvreur P, Ramseyer C

Biochim Biophys Acta Mol Basis Dis. 2022 12 7;1869(2):166614

Novel fat taste receptor agonists curtail progressive weight gain in obese male mice.

Khan AS, Hichami A, Murtaza B, Louillat-Habermeyer ML, Ramseyer C, Azadi M, Yesylevskyy S, Mangin F, Lirussi F, Leemput J, Merlin JF, Schmitt A, Suliman M, Bayardon J, Semnanian S, Jugé S, Khan NA

Cell Mol Gastroenterol Hepatol. 2022 11 18;:

Wound Healing versus Metastasis: Role of Oxidative Stress.

Lopez T, Wendremaire M, Lagarde J, Duquet O, Alibert L, Paquette B, Garrido C, Lirussi F

Biomedicines. 2022 11 2;10(11):

Design, synthesis and antitumor efficacy evaluation of a series of novel β-elemene-based macrocycles.

Qi X, Jiang S, Hui Z, Gao Y, Ye Y, Lirussi F, Garrido C, Xu L, He X, Bai R, Ye XY, Xie T

Bioorg Med Chem. 2022 10 7;74:117049

Role of human salivary enzymes in bitter taste perception.

Schwartz M, Brignot H, Feron G, Hummel T, Zhu Y, von Koskull D, Heydel JM, Lirussi F, Canon F, Neiers F

Food Chem. 2022 Mar 23;386:132798

Leptin-Induced HLA-G Inhibits Myometrial Contraction and Differentiation.

Wendremaire M, Lopez TE, Barrichon M, Zhang H, Hadi T, Ye XY, Neiers F, Bardou M, Sagot P, Garrido C, Lirussi F

Cells. 2022 Mar 10;11(6):

Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses.

Uyanik B, Goloudina AR, Akbarali A, Grigorash BB, Petukhov AV, Singhal S, Eruslanov E, Chaloyard J, Lagorgette L, Hadi T, Baidyuk EV, Sakai H, Tessarollo L, Ryffel B, Mazur SJ, Lirussi F, Garrido C, Appella E, Demidov ON

Nat Commun. 2021 06 15;12(1):3622

Lactobacillus stress protein GroEL prevents colonic inflammation.

Dias AMM, Douhard R, Hermetet F, Regimbeau M, Lopez TE, Gonzalez D, Masson S, Marcion G, Chaumonnot K, Uyanik B, Causse SZ, Rieu A, Hadi T, Basset C, Chluba J, Grober J, Guzzo J, Neiers F, Ortega-Deballon P, Demidov ON, Lirussi F, Garrido C

J Gastroenterol. 2021 Mar 29;:

Small molecule DNA-PK inhibitors as potential cancer therapy: a patent review (2010-present).

Hu S, Hui Z, Lirussi F, Garrido C, Ye XY, Xie T

Expert Opin Ther Pat. 2020 Dec 21;:

Lipoproteins LDL versus HDL as nanocarriers to target either cancer cells or macrophages.

Hadi T, Ramseyer C, Gautier T, Bellaye PS, Lopez T, Schmitt A, Sarah F, Yesylevskyy S, Minervini T, Douhard R, Dondaine L, Proukhnitzky L, Messaoudi S, Wendremaire M, Moreau M, Neiers F, Collin B, Denat F, Lagrost L, Garrido C, Lirussi F

JCI Insight. 2020 Nov 24;:

Dual inhibitors of Histone Deacetylases and Other Cancer-Related Targets: A Pharmacological Perspective.

Gao Y, Zhang H, Lirussi F, Garrido C, Ye XY, Xie T

Biochem. Pharmacol.. 2020 Sep 18;:114224

Interactions between Odorants and Glutathione Transferases in the Human Olfactory Cleft.

Schwartz M, Menetrier F, Heydel JM, Chavanne E, Faure P, Labrousse M, Lirussi F, Canon F, Mannervik B, Briand L, Neiers F

Chem. Senses. 2020 Aug 21;:

Macrophage-induced reactive oxygen species promote myometrial contraction and labor-associated mechanisms.

Wendremaire M, Hadi T, Pezze M, Barrichon M, Lopez T, Neiers F, Sagot P, Garrido C, Lirussi F

Biol. Reprod.. 2020 Mar 13;:

Steroidal glycosides from Ornithogalum dubium Houtt.

Andriamisaina N, Mitaine-Offer AC, Miyamoto T, Tanaka C, Paululat T, Lirussi F, Lacaille-Dubois MA

Phytochemistry. 2019 Feb 8;160:78-84

Characterization of rat glutathione transferases in olfactory epithelium and mucus.

Heydel JM, Menetrier F, Belloir C, Canon F, Faure P, Lirussi F, Chavanne E, Saliou JM, Artur Y, Canivenc-Lavier MC, Briand L, Neiers F

PLoS ONE. 2019 ;14(7):e0220259

Beta3 adrenergic receptor stimulation in human macrophages inhibits NADPHoxidase activity and induces catalase expression via PPARγ activation.

Hadi T, Douhard R, Dias AMM, Wendremaire M, Pezzè M, Bardou M, Sagot P, Garrido C, Lirussi F

Biochim. Biophys. Acta. 2017 Jul;1864(10):1769-1784

Restoring Anticancer Immune Response by Targeting Tumor-Derived Exosomes With a HSP70 Peptide Aptamer.

Gobbo J, Marcion G, Cordonnier M, Dias AM, Pernet N, Hammann A, Richaud S, Mjahed H, Isambert N, Clausse V, Rébé C, Bertaut A, Goussot V, Lirussi F, Ghiringhelli F, de Thonel A, Fumoleau P, Seigneuric R, Garrido C

J. Natl. Cancer Inst.. 2016 Mar;108(3):

Glutathione prevents preterm parturition and fetal death by targeting macrophage-induced reactive oxygen species production in the myometrium.

Hadi T, Bardou M, Mace G, Sicard P, Wendremaire M, Barrichon M, Richaud S, Demidov O, Sagot P, Garrido C, Lirussi F

FASEB J. 2015 Jun;29(6):2653-66

Systemic increase in human maternal circulating CD14+CD16- MCP-1+ monocytes as a marker of labor.

Bardou M, Hadi T, Mace G, Pesant M, Debermont J, Barrichon M, Wendremaire M, Laurent N, Sagot P, Lirussi F

Am J Obstet Gynecol. 2014 Jan;210(1):70.e1-9

Biphasic Erk1/2 activation sequentially involving Gs and Gi signaling is required in beta3-adrenergic receptor-induced primary smooth muscle cell proliferation.

Hadi T, Barrichon M, Mourtialon P, Wendremaire M, Garrido C, Sagot P, Bardou M, Lirussi F

Biochim Biophys Acta. 2013 May;1833(5):1041-51

Effects of leptin on lipopolysaccharide-induced remodeling in an in vitro model of human myometrial inflammation.

Wendremaire M, Mourtialon P, Goirand F, Lirussi F, Barrichon M, Hadi T, Garrido C, Le Ray I, Dumas M, Sagot P, Bardou M

Biol Reprod. 2013 Feb 21;88(2):45

Effects of leptin on lipopolysaccharide-induced myometrial apoptosis in an in vitro human model of chorioamnionitis.

Wendremaire M, Bardou M, Peyronel C, Hadi T, Sagot P, Morrison JJ, Lirussi F

Am J Obstet Gynecol. 2011 Oct;205(4):363.e1-9

SAR150640, a selective beta3-adrenoceptor agonist, prevents human myometrial remodelling and activation of matrix metalloproteinase in an in vitro model of chorioamnionitis.

Lirussi F, O'Brien M, Wendremaire M, Goirand F, Sagot P, Dumas M, Morrison JJ, Bardou M

Br J Pharmacol. 2010 Mar;159(6):1354-66

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