Glycated albumin levels in roe deer: a marker of body condition modulated by environmental quality.

Fiche publication

Date publication

octobre 2026

Journal

Oecologia

Auteurs

Membres identifiés du Cancéropôle Est :
Mme SCHAEFFER-REISS Christine

Tous les auteurs :
Duval C, Rey B, Lemaître JF, Gilot-Fromont E, Gaillard JM, Pellerin M, Jaramillo-Ortiz S, Schaeffer-Reiss C, Bertile F, Criscuolo F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/42944902

Résumé

In humans, it is now widely accepted that the glycation reaction plays a major role in the senescence process, as well as in the development of associated pathologies. While the links between glycation and senescence have also been studied in laboratory animal models, they have hardly been studied in the wild. We therefore investigated the links between glycation and senescence in two populations of roe deer (Capreolus capreolus) facing different environmental conditions, in which demographic and phenotypic senescence are well documented. Individuals of known age were captured in two years of differing quality. Individual data were collected (body mass, glycemia, sex), and we measured glycated albumin levels (GA) as well as six biochemical parameters known to show senescence in this species. We found that GA did not correlate with age, blood glucose, or sex, but varied between populations and years. In the population living in the low-quality environment, GA was negatively associated with inflammatory status while GA was positively associated with body mass. Overall, GA appears to reflect aspects of physiological condition and individual performance in an environment-dependent context, rather than senescence.