Leukocyte activation and inflammation in acute myocardial infarction: novel insights from cell population data.

Fiche publication

Date publication

juillet 2026

Journal

Frontiers in immunology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr PAIS DE BARROS Jean-Paul , Pr MASSON David

Tous les auteurs :
Leleu D, Nguyen M, Guy J, Farnier M, Chagué F, Collas L, Machado M, Gougeon M, de Barros JP, Bichat F, Maza M, Cottin Y, Masson D, Zeller M

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/42490811

Résumé

Immune dysregulation is strongly involved in acute myocardial infarction (AMI), driving sustained inflammation and myocardial damage. A better understanding of the immune cell response to AMI is needed, beyond neutrophil and monocyte counts. Cell Population Data (CPD) analysis, including granularity (SSC), size (FSC), activation (SFL), and heterogeneity indices, offers deeper insights into the dynamics of leukocyte populations.