Fiche publication
Date publication
août 2026
Journal
Liver international : official journal of the International Association for the Study of the Liver
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DUBOIS-POT-SCHNEIDER Hélène
Tous les auteurs :
Lelou E, Rauch C, Dubois-Pot-Schneider H, Dufresne M, Zekri Yazdi A, Guillout M, Cano L, Desquilles L, Nesseler N, Bourgeois M, Bendavid C, Massart J, Musso O, Corlu A, Aninat C
Lien Pubmed
Résumé
The sympathetic nervous system is involved in the progression and aggressiveness of several cancers, including hepatocellular carcinoma (HCC). However, the specific effects of sympathetic innervation and catecholamines on tumour hepatocyte behaviour remain poorly understood. In this study, we aimed to investigate the role of sympathetic fibres and catecholamines in the progression of HCC.
Mots clés
differentiated HepaRG‐hepatocytes, epinephrine, hepatocellular carcinoma, norepinephrine, sympathetic innervation, α1A‐ and β2‐adrenoreceptors
Référence
Liver Int. 2026 08;46(8):e70775
