Fiche publication


Date publication

août 2026

Journal

American journal of respiratory cell and molecular biology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr FLACHER Vincent


Tous les auteurs :
Foisset F, Lehalle C, Nasri A, Bourdais C, Urena C, Morichon L, Cœur A, Petit A, Vachier I, Muller Q, Flacher V, Chakir J, Massiera G, Sridurai V, Ahmed E, Assou S, Bourdin A, Frossard N, De Vos J

Résumé

Derived iPSCs airway epithelium are challenging given their dependency on the mesenchymal compartment. We hypothesized that growing vAFE cells on well-organized stiff matrix precolonized by adult pulmonary fibroblasts would improve epithelial differentiation yield and maturity.

Mots clés

Bronchial epithelium, Cell differentiation, Fibroblast, extracellular matrix, hiPSCs

Référence

Am J Respir Cell Mol Biol. 2026 08 8;: