Fiche publication
Date publication
août 2026
Journal
American journal of respiratory cell and molecular biology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FLACHER Vincent
Tous les auteurs :
Foisset F, Lehalle C, Nasri A, Bourdais C, Urena C, Morichon L, Cœur A, Petit A, Vachier I, Muller Q, Flacher V, Chakir J, Massiera G, Sridurai V, Ahmed E, Assou S, Bourdin A, Frossard N, De Vos J
Lien Pubmed
Résumé
Derived iPSCs airway epithelium are challenging given their dependency on the mesenchymal compartment. We hypothesized that growing vAFE cells on well-organized stiff matrix precolonized by adult pulmonary fibroblasts would improve epithelial differentiation yield and maturity.
Mots clés
Bronchial epithelium, Cell differentiation, Fibroblast, extracellular matrix, hiPSCs
Référence
Am J Respir Cell Mol Biol. 2026 08 8;: