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Date publication

août 2026

Journal

European heart journal. Quality of care & clinical outcomes

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GUILLEMIN Francis


Tous les auteurs :
Hosseini K, Girerd N, Roubille F, Monzo L, Baudry G, Epstein J, Guillemin F, Boivin JM

Résumé

Tafamidis has been demonstrated to improve survival and quality of life in transthyretin amyloid cardiomyopathy (ATTR-CM). However, its cost-effectiveness has been reported to exceed the threshold of $100,000/quality-adjusted life years [QALY] in the US healthcare system. This study aimed to evaluate costs associated with utilities (QALYs) gained for ATTR-CM in France, Spain, Germany, and the United Kingdom (UK), and to conduct a deterministic modelling study using case-scenarii based on various assumptions at a European level.

Mots clés

Cardiac amyloidosis, Cost-effectiveness, QALY, TTR stabilizer, Transthyretin, Treatment

Référence

Eur Heart J Qual Care Clin Outcomes. 2026 08 18;: