Fiche publication
Date publication
mai 2026
Journal
Journal for immunotherapy of cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Dr AMARAL Teresa Maria
Tous les auteurs :
Mandalà M, Chen MF, Sullivan RJ, Sergi MC, Postow M, Lawless AR, Effiom D, Peres T, Lorigan PC, Serra-Bellver P, Dummer R, Amaral T, Rasch ML, Giannarelli D, Vitale MG, Helgadottir H, Robert C, Ubaldi M, Johnson DB, Del Vecchio M, Indini A, Suijkerbuijk KPM, Nathan P, Carter T, Neyns B, Dirven I, Pires da Silva I, Menzies AM, Zimmer L, Livingstone E, Depenni R, Kähler K, Hauschild A, Spagnolo F, Di Giacomo AM, Arance A, Merelli B, Quaglino P, Rossi E, Tucci M, Guida M, Muñoz-Couselo E, Long GV, Larkin J, Ascierto PA
Lien Pubmed
Résumé
Nivolumab plus ipilimumab (COMBO) is the standard treatment for asymptomatic melanoma brain metastases (MBM), but current guidelines do not provide specific recommendations for treatment discontinuation in responding patients. This study aimed to evaluate outcomes after COMBO discontinuation within 24 months and the role of continuing treatment beyond 24 months.
Mots clés
Immunotherapy, Skin Cancer
Référence
J Immunother Cancer. 2026 05 4;14(5):