Sputum Inflammatory Patterns Are Associated With Distinct Clinical Characteristics in Patients with Occupational Asthma Independently of the Causal Agent.

Fiche publication

Date publication

avril 2024

Journal

Journal of investigational allergology & clinical immunology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GODET Julien

Tous les auteurs :
Migueres N, Vandenplas O, Walusiak-Skorupa J, Wiszniewska M, Munoz X, Romero-Mesones C, Suojalehto H, Lindström I, van Kampen V, Merget R, Mason P, Maestrelli P, Sastre J, Quirce S, Rifflart C, Godet J, de Blay F,

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/36377541

Résumé

Background: Clinical heterogeneity in sensitizer-induced occupational asthma (OA) and its relationship to airway inflammatory profiles remain poorly elucidated. Objectives: To further characterize interactions between induced sputum inflammatory patterns, asthma-related outcomes, and the high- or low-molecular-weight category of causal agents in a large cohort of patients with OA.