A multidimensional analysis of neuropsychiatric lupus: clinical, biological and imaging insights from systematic evidence.

Fiche publication

Date publication

mars 2026

Journal

Frontiers in immunology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DE SEZE Jérôme

Tous les auteurs :
Matmat K, Jamann H, Maazouzi A, Bigaut K, Maitre M, De Seze J, Mensah-Nyagan AG, Jeltsch-David H

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/41918728

Résumé

Neuropsychiatric systemic lupus erythematosus (NPSLE) is among the most challenging manifestations of systemic lupus erythematosus (SLE), affecting the central and peripheral nervous systems with diverse symptoms. Despite its prevalence, the diagnosis and management of NPSLE remain complex due to the heterogeneity of clinical presentations and the lack of specific biomarkers. This study aims to synthesize data from case reports to better understand the clinical, biological, and imaging features of NPSLE.