Fiche publication
Date publication
août 2014
Journal
Pathologie-biologie
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DECOT Véronique
Tous les auteurs :
Calmels B, Boulanger F, Baudoux E, Decot V, Fawaz A, Giraud C, Hivert B, Garderet L, Milpied N, Yakoub-Agha I,
Lien Pubmed
Résumé
Thousands of autologous and at less extent allogeneic hematopoietic stem cells (HSC) bags are cryopreserved in France. The majority of autologous HSC grafts are used within a year after collection. However, many bags are still unused and cryopreserved for many years. In France and on a European scale, the ever-growing number of cryopreserved bags represents a real economic health concern. Indeed, the cost of storage is about 100€ per bag and per year. In addition, quality and therapeutic value of these long-term cryopreserved grafts needs to be evaluated. In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapies (SFGM-TC) set up its fourth annual series of workshops which brought together practitioners from its member centers across France. These workshops took place in September 2013 in Lille. In this article, we addressed the issue of the destruction of long-term cryopreserved grafts be them autologous or allogeneic and provide recommendations regarding their destruction.
Mots clés
Costs and Cost Analysis, Cryopreservation, economics, France, Hematopoietic Stem Cell Transplantation, standards, Hematopoietic Stem Cells, Humans, Medical Waste Disposal, Quality Control, Registries, Time Factors, Transplantation, Homologous
Référence
Pathol. Biol.. 2014 Aug;62(4):221-5
