Imaging growth and isocitrate dehydrogenase 1 mutation are independent predictors for diffuse low-grade gliomas.

Date publication

août 2014

Journal

Neuro-oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr TAILLANDIER Luc

Tous les auteurs :
Gozé C, Blonski M, Le Maistre G, Bauchet L, Dezamis E, Page P, Varlet P, Capelle L, Devaux B, Taillandier L, Duffau H, Pallud J

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/24847087

Résumé

We explored whether spontaneous imaging tumor growth (estimated by the velocity of diametric expansion) and isocitrate dehydrogenase 1 (IDH1) mutation (estimated by IDH1 immunoexpression) were independent predictors of long-term outcomes of diffuse low-grade gliomas in adults.

Mots clés

Adult, Aged, Brain Neoplasms, genetics, Female, Genetic Testing, Glioma, genetics, Humans, Isocitrate Dehydrogenase, genetics, Male, Middle Aged, Mutation, genetics, Neoplasm Grading, Prognosis, Retrospective Studies

Référence

Neuro-oncology. 2014 Aug;16(8):1100-9