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Date publication
février 2026
Journal
Inorganic chemistry
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ELHABIRI Mourad
Tous les auteurs :
Hmadeh M, Mazan V, Rodriguez-Lucena D, Hoegy F, Platas-Iglesias C, Mislin GLA, Elhabiri M
Lien Pubmed
Résumé
In this study, we investigate three members of the HPTC family─the monomeric ligand and the bipodal ligands and , HPTC = 2-(2-hydroxyphenyl)-thiazole-4-carboxamide─to elucidate their acido-basic behavior, photophysical characteristics, and metal-binding properties. Protonation studies revealed that phenolate and carboxylate sites significantly influence fluorescence responses, including tautomeric equilibria and ESIPT processes. forms mono- and bis-chelates with Fe(III) and Ni(II), while and yielded stable monochelates with Fe(III) and other divalent metal ions. Hydrolysis of ester functionalities in markedly enhances Cu(II) complex stability relative to . Electrochemical measurements on demonstrate strong Fe(III)/Fe(II) selectivity, and kinetic data support a dissociative ligand exchange mechanism limited by metal desolvation. Overall, the presence of carboxamide and carboxylate groups plays a pivotal role in tuning metal affinity and reactivity.
Référence
Inorg Chem. 2026 02 18;:
