Real-time detection of fast and thermal neutrons in radiotherapy with CMOS sensors.

Date publication

mars 2017

Journal

Physics in medicine and biology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr MEYER Philippe

Tous les auteurs :
Arbor N, Higueret S, Elazhar H, Combe R, Meyer P, Dehaynin N, Taupin F, Husson D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/28192285

Résumé

The peripheral dose distribution is a growing concern for the improvement of new external radiation modalities. Secondary particles, especially photo-neutrons produced by the accelerator, irradiate the patient more than tens of centimeters away from the tumor volume. However the out-of-field dose is still not estimated accurately by the treatment planning softwares. This study demonstrates the possibility of using a specially designed CMOS sensor for fast and thermal neutron monitoring in radiotherapy. The 14 microns-thick sensitive layer and the integrated electronic chain of the CMOS are particularly suitable for real-time measurements in γ/n mixed fields. An experimental field size dependency of the fast neutron production rate, supported by Monte Carlo simulations and CR-39 data, has been observed. This dependency points out the potential benefits of a real-time monitoring of fast and thermal neutron during beam intensity modulated radiation therapies.

Mots clés

Fast Neutrons, therapeutic use, Gamma Rays, therapeutic use, Monte Carlo Method, Radiometry, instrumentation, Radiotherapy, instrumentation, Radiotherapy Dosage

Référence

Phys Med Biol. 2017 03 7;62(5):1920-1934