Fiche publication
Date publication
février 2020
Journal
Cancers
Auteurs
Membres identifiés du Cancéropôle Est :
Dr AMARAL Teresa Maria
Tous les auteurs :
Forschner A, Hilke FJ, Bonzheim I, Gschwind A, Demidov G, Amaral T, Ossowski S, Riess O, Schroeder C, Martus P, Klumpp B, Gonzalez-Menendez I, Garbe C, Niessner H, Sinnberg T
Lien Pubmed
Résumé
Mucosal and acral melanoma respond worse to immune checkpoint inhibitors (ICI) than cutaneous melanoma. as well as amplifications are supposed to be associated with hyperprogression on ICI in diverse cancers. We therefore investigated the response of metastatic acral and mucosal melanoma to ICI in regard to or amplifications and melanoma type.
Mots clés
EGFR, MDM2, MDM4, acral melanoma, hyperprogression, immune checkpoint inhibitors, mucosal melanoma
Référence
Cancers (Basel). 2020 02 26;12(3):