Fiche publication
Date publication
juillet 2020
Journal
Research and practice in thrombosis and haemostasis
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MARCAIS Ambroise
Tous les auteurs :
Lasne D, Pascreau T, Darame S, Bourrienne MC, Tournoux P, Philippe A, Ziachahabi S, Suarez F, Marcais A, Dupont A, Denis CV, Kauskot A, Borgel D
Lien Pubmed
Résumé
Correct diagnosis of the cause of thrombocytopenia is crucial for the appropriate management of patients. Hyposialylation/desialylation (characterized by abnormally high β-galactose exposure) accelerates platelet clearance and can lead to thrombocytopenia. However, the reference range for β-galactose exposure in healthy individuals has not been defined previously.
Mots clés
N‐acetylneuraminic acid, blood platelets, galactose, platelet count, references values
Référence
Res Pract Thromb Haemost. 2020 07;4(5):813-822
