Fiche publication
Date publication
janvier 2026
Journal
Cell communication and signaling : CCS
Auteurs
Membres identifiés du Cancéropôle Est :
Dr PAIS DE BARROS Jean-Paul
,
Dr JACQUIN Elise
Tous les auteurs :
Bringer MA, Manceau S, Al Azzaz J, Buteau B, Proukhnitzky L, Aumeunier A, Bermúdez-Humarán LG, Chain F, Daniel C, Jacquin E, Mlamla Z, de Barros JP, Ducassou JN, Couté Y, Faure G, Acar N, Rieu A, Lapaquette P
Lien Pubmed
Résumé
Autophagy-related processes are crucial for maintaining cellular homeostasis in eukaryotic organisms. While alterations of these processes have been strongly linked to specific human disorders, including inflammatory bowel disease, neurodegenerative diseases, and metabolic syndromes, long-term autophagy stimulation appears to be safe and to extend lifespan in model organisms. Several studies indicate that gut microbiota or derived metabolites can modulate host autophagy at the gut mucosa level but also in peripheral organs. Here, we investigated in vitro and in vivo the potential of bacterial species commonly used in food fermentation (ferments) or for their health benefits (probiotics) to modulate host autophagy.
Mots clés
Aging, Autophagy, Ferment, Gut, Membrane vesicles, Probiotic, Retina
Référence
Cell Commun Signal. 2026 01 6;:
