Combined effects of mesenchymal stromal cells and antibiotic therapy on Enterobacter ventilator-associated pneumonia in rabbits.

Date publication

janvier 2026

Journal

Respiratory research

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BENSOUSSAN Danièle , Dr BOIDOT Romain , Pr MASSON David

Tous les auteurs :
Jacquier M, Laroye C, Bensoussan D, Nguyen S, Croisier D, Richard C, Boidot R, Masson D, Charles PE, Blot M

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/41501819

Résumé

Although mesenchymal stromal cells (MSCs) have shown promising effects in preclinical pneumonia models, their ability to improve outcomes in ventilator-associated pneumonia (VAP) remains poorly explored, despite VAP being a frequent and severe complication in critically ill patients. This study investigated whether MSCs could enhance outcomes in a rabbit VAP model.

Mots clés

Antibiotic, Immunity, Mesenchymal stromal cells, Pneumonia, Ventilator-associated pneumonia

Référence

Respir Res. 2026 01 7;: